1.Early Dental Implant Failure in Patient with Active Implant Periapical Lesions: Lesson Learnt from Two Case Reports
Nik Fatin Sarah Nik Mhd Abdul Nasser ; Nurul Qamar Salehuddin ; Nurul Ain Mohamed Yusof ; Wan Nurhazirah Wan Ahmad Kamil ; Erni Noor
Archives of Orofacial Sciences 2022;17(SUPP 1):137-148
ABSTRACT
Implant periapical lesion (IPL) is also known as retrograde peri-implantitis and as the name suggests,
it involves inflammation surrounding the apical part of the dental implants. Previously, many studies
have reported the event of IPL that further delays osseointegration, and some reported failure of
implant placement due to this disease. In this article, we described two cases of early dental implant
failure that was associated with active IPL and correlated the clinical and radiographical findings with the
histopathological findings.
Dental Restoration Failure
;
Dental Implants--adverse effects
;
Periapical Tissue
2.Discordance between Fasting Plasma Glucose (FPG) and HbA1c in Diagnosing Diabetes and Pre-diabetes in The Malaysian Cohort
Nor Azian Abdul Murad ; Noraidatulakma Abdullah ; Mohd Arman Kamaruddin ; Nazihah Abd Jalal ; Norliza Ismail ; Nurul Ain Mhd Yusof ; Norlaila Mustafa ; Rahman Jamal
Journal of the ASEAN Federation of Endocrine Societies 2021;36(2):127-132
Objective:
In this present study, we aim to evaluate the accuracy of the HbA1c relative to fasting plasma glucose (FPG) in the diagnosis of diabetes and pre-diabetes among The Malaysian Cohort (TMC) participants.
Methodology:
FPG and HbA1c were taken from 40,667 eligible TMC participants that have no previous history of diabetes, aged between 35-70 years and were recruited from 2006 – 2012. Participants were classified as normal, diabetes and pre-diabetes based on the 2006 World Health Organization (WHO) criteria. Statistical analyses were performed using ANOVA and Chi-square test, while Pearson correlation and Cohen’s kappa were used to examine the concordance rate between FPG and HbA1c.
Results:
The study samples consisted of 16,224 men and 24,443 women. The prevalence of diabetes among the participants was 5.7% and 7.5% according to the FPG and HbA1c level, respectively. Based on FPG, 10.6% of the participants had pre-diabetes but this increased to 14.2% based on HbA1c (r=0.86; P<0.001). HbA1c had a sensitivity of 58.20 (95% CI: 56.43, 59.96) and a specificity of 98.59 (95% CI: 98.46, 98.70).
Conclusion
A higher prevalence of pre-diabetes and diabetes was observed when using HbA1c as a diagnosis tool, suggesting that it could possibly be more useful for early detection. However, given that HbA1c may also have lower sensitivity and higher false positive rate, several diagnostic criteria should be used to diagnose diabetes accurately.
Diabetes Mellitus, Type 2
;
Diagnosis
Result Analysis
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