1.Retinal nerve fiber layer thickness in patients with essential tremor
Yakup Turkel ; Nurgul Ornek ; Ersel Dag ; Kemal Ornek ; Murat Alpua ; Tevfik Ogurel ; Yasar Olmez
Neurology Asia 2015;20(3):363-366
Objective: To investigate the retinal nerve fiber layer (RNFL) thickness in essential tremor (ET).
Methods: Twenty-seven eyes of 27 patients with essential tremor were included in this study. Twentyseven
eyes of 27 healthy volunteers served as controls. All eyes were examined with spectral domain
optical coherence tomography (OCT) (Retinascan Advanced RS-3000; NIDEK, Gamagori, Japan)
using image filling software program (NAVIS-EX, NIDEK, Tokyo, Japan). Results: No statistically
significant difference was detected between ET patients and control group for overall (RNFL) and
foveal retinal thickness parameters. [RNFL thickness (Average thickness p=0.86, superior average
p=0.22, inferior average p=0.24, nasal average p=0.06, temporal average p=0.88), foveal retinal
thickness p=0.63] There was no relationship between OCT parameters and age, gender and duration
of ET (all p>0.05).
Conclusion: We did not find altered RNFL and foveal thickness values in patients with ET compared to
controls. Retinal thickness changes do not seem to be a potentially useful biomarker in ET patients.
2.Retinal nerve fiber layer thickness in patients with essential tremor
Yakup Turkel ; Nurgul Ornek ; Ersel Dag ; Kemal Ornek ; Murat Alpua ; Tevfik Ogurel ; Yasar Olmez
Neurology Asia 2015;20(4):363-366
Objective: To investigate the retinal nerve fiber layer (RNFL) thickness in essential tremor (ET).
Methods: Twenty-seven eyes of 27 patients with essential tremor were included in this study. Twentyseven
eyes of 27 healthy volunteers served as controls. All eyes were examined with spectral domain
optical coherence tomography (OCT) (Retinascan Advanced RS-3000; NIDEK, Gamagori, Japan)
using image filling software program (NAVIS-EX, NIDEK, Tokyo, Japan). Results: No statistically
significant difference was detected between ET patients and control group for overall (RNFL) and
foveal retinal thickness parameters. [RNFL thickness (Average thickness p=0.86, superior average
p=0.22, inferior average p=0.24, nasal average p=0.06, temporal average p=0.88), foveal retinal
thickness p=0.63] There was no relationship between OCT parameters and age, gender and duration
of ET (all p>0.05).
Conclusion: We did not find altered RNFL and foveal thickness values in patients with ET compared to
controls. Retinal thickness changes do not seem to be a potentially useful biomarker in ET patients.
Essential Tremor