1.Impulse control behaviours in a Malaysian Parkinson’s disease population
Shahrul Azmin ; Eng Liang Tan ; Nik Jaafar Nik Ruzyanei ; Zakaria Hazli ; Azmawati Mohammed Nawi ; Zhe Kang Law ; Remli Rabani ; Wan Yahya Nafisah ; Ramesh Sahathevan ; Hui Jan Tan ; Nur Fadhlina M. Pakarul Razy ; Nor Azian Abdul Murad ; King-Hwa Ling ; Mohamed Ibrahim
Neurology Asia 2016;21(2):137-143
Background: Impulse control behaviours are repetitive and excessive activities that may be subsyndromal
and not fulfil the criteria for impulse control disorder. These activities have potential to
negatively impact on the daily lives of sufferers. We conducted a study to investigate the prevalence
of impulse control behaviours and its associated features in Parkinson’s disease in our population.
Methods: We conducted a prospective cross-sectional study on consecutive patients attending neurology
clinic. Inclusion criteria include idiopathic Parkinson’s disease patients with Hoehn & Yahr stage I-IV.
Eighty patients were enrolled and screened for impulse control behaviours using the Questionnaire
for Impulsive-Compulsive Disorder for Parkinson’s disease (QUIP). Results: Prevalence of impulse
control behaviours among our cohort was 11.3%; the features significantly associated with it were
higher level of education (p=0.02), advanced stage of disease (p=0.03) and higher levodopa dosage
(p= 0.01). The commonest impulse control behaviour in our cohort was compulsive medication use
(7.5%), followed by hobbyism (6.3%), hypersexuality (5%), compulsive buying (3.75%), punding
(2.5%), walkabout (2.5%), compulsive eating (1.25%) and pathological gambling (1.3%).
Conclusions: There is an association between impulse control behaviour and higher levodopa dosage
in a study on patients with Parkinson’s disease in Malaysia. We also found a low prevalence of
pathological gambling as compared to studies performed in the West.
Disruptive, Impulse Control, and Conduct Disorders
;
Parkinson Disease
Result Analysis
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