1.Symptomatic chronic strongyloidiasis in children following treatment for solid organ malignancies : case reports and literature review
Norsarwany Mohamad ; Abdelrahman Zueter ; Rahmah Noordin ; Ariffin Nasir ; Norsyahida Ariffin ; Madihah Basuni ; Zeehaida Mohamed
Tropical Biomedicine 2012;29(3):479-488
Strongyloidiasis is an infection caused by the intestinal nematode Strongyloides stercoralis. Infected healthy individuals are usually asymptomatic, however it is potentially fatal in immunocompromised hosts due to its capacity to cause an overwhelming hyperinfection. Strongyloidiasis could be missed during routine screening because of low and intermittent larval output in stool and variable manifestations of the symptoms. We present
two cases of strongyloidiasis occurring in children with solid organ malignancies suspected to have the infection based on their clinical conditions and treatment history for cancer. Both patients were diagnosed by molecular and serological tests and were successfully treated.
Thus, strongyloidiasis in patients undergoing intensive treatment for malignancies should be suspected, properly investigated and treated accordingly.
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