1.Imaging findings of an isolated deep cerebral venous thrombosis in the absence of superficial sinus thrombosis
Sabrilhakim Sidek ; Kartini Rahmat ; Norlisah Ramli
Neurology Asia 2015;20(2):191-195
Thrombosis of the deep cerebral venous system in the absence of superficial sinus thrombosis is a very
rare disease. The clinical and radiological findings can be diagnostically challenging due to the subtle
appearances on computed tomography (CT) scan. Magnetic resonance imaging (MRI) examination is
a preferred imaging modality to complement the CT findings for an accurate diagnosis of venous sinus
thrombosis. We present a case of this unusual condition which present as unilateral thalamic lesion
on CT scan and the role of contrast enhanced MRI with fast spoiled gradient echo (FSPGR) sequence
and 3D reconstruction which led to the diagnosis of thrombosis in the deep cerebral venous system.
Thrombosis
2.Tolosa-Hunt syndrome following recurrent facial palsies
Nortina Shahrizaila ; Norlisah Ramli ; Chong Tin Tan
Neurology Asia 2010;15(1):97-99
Tolosa-Hunt syndrome is typically associated with an infl ammatory lesion in the cavernous sinus or orbital
fi ssure, often requiring steroids for symptom resolution. In this report, we describe a case of Tolosa-Hunt
syndrome preceded by several years’ history of idiopathic recurrent facial palsies. The spontaneous
resolution of THS in our case as well as prior facial nerve involvement supports the hypothesis that
Tolosa-Hunt syndrome is part of a spectrum of idiopathic recurrent cranial neuropathy.
3.Medulloblastoblastoma with excessive nodularity: Typical imaging appearance
Win Myint Tun ; Norlisah Ramli ; Kein Seong Mun
Neurology Asia 2017;22(2):173-176
Medulloblastoma is the most common form of childhood primary brain tumour arising from the
cerebellar vermis. It is classified as WHO grade IV embryonal tumours and currently at least four
histological variants have been established. Only few case reports been published on the imaging
features of the medulloblastoma with excessive nodularity variant. We report the MRI features of a rare
case of medulloblastoma with excessive nodularity in a child which is confirmed by histopathology.
4.Primary intraventricular lymphoma with diffuse leptomeningeal spread at presentation.
Hasyma Abu HASSAN ; Norlisah M RAMLI ; Kartini RAHMAT
Annals of the Academy of Medicine, Singapore 2012;41(6):268-270
Aged
;
Brain Neoplasms
;
diagnosis
;
pathology
;
Central Nervous System Neoplasms
;
diagnosis
;
pathology
;
Fatal Outcome
;
Female
;
Humans
;
Lymphoma
;
diagnosis
;
pathology
;
Meningeal Neoplasms
;
diagnosis
;
secondary
5.Multiloculated hydrocephalus in an adult: Role of MRI FIESTA sequence in diagnosis and management
Norlisah Ramli ; Farhana Fadzli ; Kalai Arasu Muthusamy ; Chan Kam Hong
Neurology Asia 2014;19(4):425-427
This is a case of an adult patient with hypertensive intraventricular haemorrhages complicated by
hydrocephalus that failed to respond to endoscopic third ventriculostomy (ETV). High-resolution
3D Fast Imaging Employing Steady State Acquisition (FIESTA) magnetic resonance imaging (MRI)
revealed underlying multiloculated hydrocephalus. This case report highlights the appropriate sequence
and its attributes that offer adequate preoperative information detailing the ventricular system.
6.Traumatic vertebral artery dissection mimicking central pontine myelinolysis: A case report
Jaishree Sharmini ; Kheng-Seang Lim ; Norlisah Ramli ; Chong-Tin Tan
Neurology Asia 2010;15(2):167-171
A 27 year-old Chinese man, involved in a motor vehicle accident, presented with rapidly progressive
pseudobulbar palsy and spastic tetraplegia. Magnetic resonance imaging (MRI) of the brain showed central
pontine T2 hyperintensity with an unaffected outer rim, consistent with central pontine myelinolysis.
There was no hyponatraemia before MRI and he was neither an alcoholic nor malnourished. Cerebral
angiogram confi rmed the diagnosis of right vertebral artery dissection. Vertebral artery dissection
should be considered in a case with imaging suggestive of central pontine myelinolysis.
9.Mimics and diagnostic pitfalls of intracranial lesions in conventional MRI: Clues on advanced MRI
Alan Basil Peter ; Norlisah Ramli ; Kartini Rahmat ; Faizatul Izza Rozalli ; Che Ahmad Mazlan
Neurology Asia 2015;20(2):161-165
Objective: To delineate and differentiate between late subacute hemorrhage and intracranial lipomas
in clinically available conventional and advanced MR sequences. Methods: Two cases of late subacute
hemorrhage and two cases of intracranial lipoma were reviewed with CT scans and 3.0T scanner MRI.
The sequences evaluated in MRI were T1-weighted (T1W) fast spin echo (FSE), T2-weighted (T2W)
FSE, gradient echo T2*-weighted (GRE T2*W) images, diffusion weighted (DWI), apparent diffusion
coefficient (ADC) and multivoxel spectroscopy. Results: Late subacute hemorrhage and intracranial
lipoma have similar imaging features on T1W, T2W FSE with blooming artefact at the margins on
GRE T2*W. However on GRE T2*W sequence, the central area of lipoma demonstrates low signal;
while hemorrhage demonstrates high signal. In DWI, late subacute hemorrhage shows hyperintensity;
while in lipoma there is loss of signal.
Conclusion: Awareness of the potential pitfalls in standard sequence are important, as these entities
appear to have similar T1W/ T2W characteristic with blooming artefact on T2*W. Knowing the
distinctive central signal intensity pattern on GRE T2W* and DWI is therefore essential to differentiate
between these lesions as there are differences to their clinical management.
Magnetic Resonance Imaging
10.MRI findings of orbicularis oculi hypertrophy due to heavy resistance training on the inferior orbital rim
Hasyma Abu Hassan ; Norlisah Mohd Ramli ; Kenneth CS Fong ; Khean-Jin Goh
Neurology Asia 2013;18(4):427-429
Increase in cross-sectional muscle area of major muscle groups associated by heavy resistance training
has been well documented. However, there has been no published article of changes in the inferior
orbicularis oculi muscle when heavy resistance training is applied. We present a case of inferior
orbicularis hypertrophy detected on MRI in a gentleman who practised heavy resistance training
using his lower eyelids.