1.Human Platelet Antigen Datasets for Malays, Chinese, and Indians in Peninsular Malaysia
Che Ghazali Norul HAJAR ; Zulkifli ZEFARINA ; Nor Suhaila Md. RIFFIN ; Tuan Hulwani Tuan MOHAMMAD ; Mohd Nazri HASSAN ; Ameer Mohamed DAFALLA ; Gehad ELGHAZALI ; Geoffrey Keith CHAMBERS ; Hisham Atan EDINUR
Annals of Laboratory Medicine 2020;40(6):493-499
2.Environmental Factors of Commuting Accidents among Firefighter Drivers in Peninsular Malaysia: A Case study
Norfaqihah Mohtar ; Rosnah Ismail ; Nor Hisham Mohammad ; Mohammad Paisal Adam ; Mohammad Hamdan Wahid ; Mohd Hasni Ja&rsquo ; afar
International Journal of Public Health Research 2023;13(no.2):1784-1791
Introduction:
Commuting accidents (CAs) caused significant detrimental impacts on the Fire
and Rescue Department of Malaysia (FRDM). Therefore, this study aims to
identify factors of CA by mainly focusing on environmental factors
Methodology:
The qualitative data was obtained from FRDM accident investigation reports
from five states (Kedah, Selangor, Kuala Lumpur, Negeri Sembilan and Johor)
between 2017-2021. The data were analysed using content analysis.
Results:
Four environmental factors that contribute to CA were identified. The factors
were environmental conditions (rainfall, strong wind, light glare, and
insufficient lighting), time (twilight and night time), road physical conditions
(hilly road, curvy, steep, and narrow road, weak manhole cover, soft ground,
wet and slippery road), and road environment (traffic congestion and sudden
animal crossing)
Conclusion
These findings provide environment-related hazards input for risk assessment
and management of CA in FRDM, as well as valuable information for future
research. Therefore, it has the potential to improve road safety for firefighters,
the general public, and animals
3.Allelic Diversity of the Hemochromatosis Gene (HFE) in Malays, Chinese and Indians
Che Ghazali Norul Hajar ; Suhaida Md. Akhir ; Zulkafli Zefarina ; Nor Suhaila Md. Riffin ; Tuan Hulwani Tuan Mohammad ; Mohd Nazri Hassan ; Sabreena Safuan ; Mohd Yusmaidie Aziz ; Siddhartha Pati ; Geoffrey Keith Chambers ; Hisham Atan Edinur
Malaysian Journal of Medicine and Health Sciences 2021;17(No.3):49-54
Introduction: Hereditary hemochromatosis (HH) is an autosomal recessive disorder that causes accumulation of iron in circulating blood and organs. The disease is associated with H63D, S65C and C282Y variants of the haemochromatosis (HFE) gene and, if not treated can cause organ damage and may prove fatal. The main objectives of the present survey were to screen these genetic variants and establish risk profiles for developing HH in Malays, Chinese and Indians. Methods: A total of two hundred and twenty-two unrelated and healthy individuals together representing Malay, Chinese and Indian ethnicities in Malaysia were scored for the H63D, S65C and C282Y variants using a polymerase chain reaction-restriction fragment length polymorphism technique. Results: There are clear differences in H63D, S65C and C282Y allele and genotype frequency distributions between Malays, Chinese and Indians. In particular, H63D is more common in Chinese (5.19%) and Indians (7.29%), while S65C is more common in Malays (1.03%) and Chinese (1.04%). In addition, a susceptibility genotype for HH (the compound heterozygote for C282Y and H63D) was only detected in Indians (0.02%). Conclusion: Overall, our study is the first to provide data on the prevalence of H63D, S65C, and C282Y genetic variants and HH risk profiles for Malays, Chinese and Indians.