1.Solitary Fibrous Tumour of the Submandibular Region: A Rare Entity
Noor Liza Ishak ; Primuharsa Putra Sabir Athar Husin ; Suria Hayati Md Pauzi ; Isa Mohd Rose ; Mohd Razif Mohamad Yunus
Malaysian Journal of Medicine and Health Sciences 2016;12(2):60-63
Solitary fibrous tumours of the head and neck region are
extremely rare. The clinical diagnosis is often difficult to
establish, and this lesion may be indistinguishable from other
soft tissue neoplasms. An 18-year old Chinese gentleman
presented with a painless right submandibular swelling which
was increasing in size for eight months. A computed
tomography scan showed a well-defined solid mass measuring
about 2.0 x 2.96 cm in the submandibular region. The tumour
was resected and was confined within its capsule.
Immunohistochemical staining was strongly positive for CD34,
CD 99, and vimentin and negative for desmin, smooth muscle
actin (SMA), cytokeratin, S100 and CD68. The microscopic and
immunohistochemical profile were compatible with solitary
fibrous tumour. Distinguishing solitary fibrous tumours from
various spindle neoplasms can be difficult. In view of the
resemblance, immunohistochemical staining can help
differentiate solitary fibrous tumour from spindle neoplasm.
Neoplasms, Tumors, Cancer
2.Relationship between Demodex sp. Infestation and Acne Problem among Adults in Klang Valley, Malaysia
Chew Poh Ling ; Noor Hayati Mohd Isa ; Siti Nor Azreen Abdul Manap ; Ismail Mohd Ghauth ; Aisah Md Yunus
Malaysian Journal of Health Sciences 2010;8(1):45-48
Demodex sp. is a skin ectoparasite known as follicle mite. The objectives of this study were to determine the prevalence of Demodex sp. infestation among Malaysian adults with age ranges from 20 to 29 years old in Lembah Klang and to determine the relationship between the infestation status and gender and acne problem on face. This is the first study that has been conducted in Malaysia to determine the prevalence of Demodex sp. infestation. A total of 350 people participated in this study. Samples were selected by stratified random sampling. Skin scraping was carried out on
forehead, nose, cheeks and chin. All specimens were mounted in Hoyer’s medium and studied under light microscope. Questionnaires were distributed to the subjects to identify acne problem on their skin conditions. The overall prevalence of Demodex sp. infestation was 18.9% with higher prevalence in males (25.7%) compared to females (12.0%). There
was no significant difference between acne problem and Demodex sp. infestation. In conclusion, infestation of Demodex sp. was detected in a fifth of the subjects, with men had more problems.
3.Effects of Temperatures on Larval Development of Chrysomya megacephala (Fabricius) and Chrysomya rufifacies (Macquart) (Diptera: Calliphoridae): Application in Forensic Science
Ahmad Firdaus Mohd Salleh ; Anita Talib ; Mohamed Abdullah Marwi ; Noor Hayati Mohd Isa ; Syamsa Rizal Abdullah ; Raja Muhammad Zuha Raja Kamal Bashah ; Baharudin Omar.
Malaysian Journal of Health Sciences 2009;7(2):89-96
Chrysomya megacephala (Fabricius) and Chrysomya rufifacies (Macquart) are two important species of blow flies that could be utilised as indicators to
estimate the Post Mortem Interval (PMI) of corpses in forensic science. Determination of PMI of corpses is based on the larva size and its development
stages. Development studies of eggs, larvae and pupae of Ch. megacephala and Ch. rufifacies at 27ºC, 30ºC and 33ºC were carried out using an insect growth chamber. Data from these studies were used to construct growth curves
and Accumulated Degree Hours (ADH) for both species. Ch. megacephala needs 9.15 days to complete one life cycle at 27ºC, 8.54 days at 30ºC and 6.76 days
at 33ºC. Development for Ch. rufifacies is slower than Ch. megacephala and takes 9.92 day at 27ºC, 9.13 days at 30ºC and 7.44 days at 33ºC. Eggs of the
two species hatch faster at 33ºC compared to the two other temperatures. Low value of ADH shows shorter life cycle of that particular species. This study’s
findings are useful in estimating PMI of the corpses found under various environmental temperatures.