Studies on relationship between insulin secretion and 8 meridian points, namely St-39, Ren-12, LI-11, UB-20, UB-18, St-36, Sp-8, and Liv-3 which are extensively used for the treatment of diabetes mellitus, revealed that LI-11 and UB-18 are closely related to secretion of insulin.
The twelve segmentations of Hirata, LI-11 corresponds to the 5th response zone of upper extremity region and UB-18 to the 5th response zone of truncal region, respectively. In order to investigate relationship between insulin secretion and the 5th response zone of Hirata's twelve segmentations, GB-10 of capital region, St-3 of collar region, SI-16 of facial region and Sp-6 of lower extremity region were stimulated by placing needle during oral glucose loading and insulin secretion was evaluated.
As a result, none of the meridian point locating in the 5th response zone in each region of Hirata's twelve segmentations showed positive relation to insulin secretion, except LI-11 of upper extrmity region and UB-18 of truncal region.

The term, propagated sensation along the channels (PSC) means the peculiar sensation expeerienced by some people along thier meridians when given acupunctural stimulation of acupoints.
In the present study, the incidence of PSC in outpatients who were undergoing acupuncture treatment was investigated.
Low frequency electrical stimulation was performed through press needles at twenty-six points: the twelve terminal points of the twelve regular meridians and the Inner-Zhiyin points of both sides. PSC was assessed on a four-grade basis after the manner carried out in China.
The incidence of PSC was significantly high among the outpatients compared with that among healthy youth. Patients with hypertension or posttraumatic neck syndrome showed higher incidence of PSC than the other patients.