1.The Safety of AstaREAL, an Astaxanthin Product Derived from Haematococcus pluvialis
Jiro TAKAHASHI ; Nobuko HONGO ; Shiro OHKI ; Akitoshi KITAMURA ; Hiroki TSUKAHARA ; Hoko KYO ; Nobutaka SUZUKI
Japanese Journal of Complementary and Alternative Medicine 2015;12(1):9-17
Astaxanthin, a red carotenoid, has been known to possess excellent antioxidant activity and various biological activities, thereby attracting attention as a functional food material.The safety of astaxanthin administered orally has been demonstrated in human clinical studies for about ten years.In this review, we summarized the clinical studies related to safety, as well as studies on genotoxicity, and acute and subchronic toxicity, with a focus on AstaREAL, an astaxanthin product derived from Haematococcus pluvialis which has been reported in numerous human clinical studies to be safe and to have multiple health benefits.Furthermore, based on the latest research, we reviewed the effect of astaxanthin on drug-metabolizing enzymes involved in drug interactions, and concluded that the safety of H. pluvialis-derived astaxanthin, AstaREAL has been widely confirmed.
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