In the present study, we investigated the effects of plasma cluster ions on moisturizing skin and increasing comfort sensation in healthy female volunteers. Thirty-two healthy women who often experienced dry skin participated in a randomized crossover trial. We evaluated skin moisture using the Corneometer CM825 and comfort sensation using the visual analogue scale. Plasma cluster ion concentrations of 25000 pcs/cm3 increased skin moisture, while concentrations of 7000 pcs/cm3 increased comfort sensation. These results suggest that plasma cluster ions have an effect on skin moisture contents and comfort sensation.
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