Objective To study on the effect of health promotion on the prognosis of patients with acute myocardial infarction(AMI)combined with diabetes.Methods 104 patients of AMI complicated with diabetes were:randomly divided into the control and the experimental groups with 52 cases in each group.Two groups were conferred fixed medicine and other clinical interventions as well as programmed education during their hospitalization.After discharge.the experimental group continued to implement health promotion for six months'follow-up.After six months,the fasting blood glucose,postprandial blood glucose,triglyceride,cholesterol,clinic cost,level of knowledge and behavior were compared between the two groups after six months.Results after six months,there was significant difference between two groups in blood glucose,postprandial blood glucose,triglyceride,cholesterol clinic cost,level of knowledge and behavior(P＜0.05).Rate of readmission and mortality rate were not stanstically different(P＞0.05).Conclusions Health promotion can improve capital clinical index of the patients,decrease the cost and promote the life quality of patients.