Objective To evaluate the efficacy of combined general anesthesia with epidural block(CGEA) for choledocholithotomy in the elderly. Methods Sixty patients, ASA I-II, scheduled for elective choledocholithotomy were divided into single general anesthesia group(control group) and CGEA group(study group). Hemodynamics, general anesthesia dosage and awakening time were observed. Results In control group, patients had higher stress responses while intubated and their BP and HR were signifficantly increased after intubation(P