1.A review of medical image compression techniques
International Journal of Biomedical Engineering 2008;31(2):77-81
As the increasing of digital imagilag modalities,a close-at-hand challenge to deal with is the storage and transmission requirement of enormous data of medical images.Compression is one of the indispensable techniques to solve this problem.A comprehensive review and discussions are made in this paper over the medial image compression techniques applied in medical image domain,including the latest achievements in this field.Different compression algorithm including ROI-based coding,lossless compression,DWT,neural net are introduced and some quality evaluation methods are introduced.Foreground of the field is given from our point of view.
2.Tinidazole-induced Adverse Drug Reactions:Literature Analysis of 63 Cases
China Pharmacy 2005;0(17):-
OBJECTIVE:To study the general pattern and characteristics of adverse drug reactions(ADR) induced by tinidazole.METHODS:Tinidazole-induced ADR cases reported in the internal pharmaceutical journals retrieved from Jan.1994 to Jun.2006 were analyzed statistically.RESULTS:The ADR induced by tinidazole were diversified in clinical manifestation,but allergic response was the most common type,followed by the lesion of nervous system and digestive system etc.CONC-LUSION:Clinicians should attach great importance to the ADR induced by tinidazole.
3.Effect of letrozole combined with clomiphene on women with polycystic ovary induced infertility and the effect on MMP-9, VEGF and HGF levels
Chinese Journal of Biochemical Pharmaceutics 2017;37(4):311-313
Objective To research the effect of letrozole combined with clomiphene on women with polycystic ovary induced infertility and the effect on matrix metalloproteinases-9(MMP-9),vascular endothelial growth factor(VEGF)and hepatocyte growth factor(HGF)levels.Methods 108 patients with polycystic ovary syndrome combined with infertility from February 2013 to August 2015 in our hospitolwere divided into control group and experimental group by lottery,54 cases in each groups,control group treated with clomiphene,the experimental group based on control group treatment with letrozole,the linical curative effect,MMP-9,VEGF and HGF level,sex hormones,insulin resistance index,adverse drug reactions of two groups were compared.Results The number of ovulation,advantage of ovulation number,normal rate of menstruation,ovulation rate and pregnancy ratesofin experimental group was higherthan the control group,the difference was statistically significant(P<0.05).The MMP-9,VEGF and HGF levels of experimental group was lower than the control group,the difference was statistically significant(P<0.05).The sex hormone level of experimental group was better than that of control group(P<0.05).The adverse reactions was no differences between the two groups.Conclusion The efficacy of letrozole combined with clomiphene in treatment of polycystic induced infertility,can inhibits MMP-9,VEGF and HGF expression,and with high safety.
4.Study on Bilingual Teaching in Higher Medical Education and their Possible Solutions in Local Medical College for Nationalities
Chinese Journal of Medical Education Research 2006;0(10):-
The paper aimed to find out the present situation of bilingual teaching in higher medical education of the local medical college for nationalities and the results of the questionnaire showed that there were still some problems in the bilingual teaching education in these years.And some constructive suggestions were put forward.
5.Expression and correlation of EHD2 and E-cadherin in hepatocellular carcinoma
Jinxia LIU ; Lishuai QU ; Cuihua LU ; Wenkai NI ; Runzhou NI
Chinese Journal of Clinical Oncology 2017;44(3):118-122
Objective:To investigate the expression and correlation of EHD2 and E-cadherin in hepatocellular carcinoma (HCC). Meth-ods:Western blot and immunohistochemistry were used to detect the expression of EHD2 and E-cadherin in HCC specimens and adja-cent noncancerous tissues. The correlations of EHD2 and E-cadherin with the clinicopathological characteristics and prognosis of pa-tients were further analyzed using Pearsonχ2 test and Kaplan-Meier method. Results:EHD2 expression, along with E-cadherin, was markedly reduced in HCC tissues than in adjacent noncancerous tissues. Moreover, EHD2 and E-cadherin expression were correlated with histological grade, microvascular invasion, and lymph node metastasis (P<0.05). Kaplan-Meier survival analysis showed that HCC patients with decreased EHD2 and E-cadherin expression had shorter overall survival time than those with higher expression. Conclu-sion:The abnormal expression of EHD2 and E-cadherin possibly promote HCC. Detection of EHD2 and E-cadherin may be valuable for diagnosing HCC and evaluating malignancy extent and prognosis.
6.Diagnosis and surgical management of acute gangrenous cholecystitis early after endoscopic sphincterotomy and endoscopic retrograde cholangiopancreatography
Jie NI ; Zhongyao LUO ; Bei LU
Chinese Journal of Hepatobiliary Surgery 2009;15(1):17-19
Objective To discuss the diagnosis and surgical management of acute gangrenous cholecystitis (AGC) early after EST and ERCP. Methods Clinical and pathological data of 1468 cases receiving EST and ERCP in our hospital from 2005 to 2007 were retrospectively analyzed. Results AGC occurredin 16 cases and the incidence was 1.09%. Its main manifestations were pain in the right upper abdomen with local pertonitis and fever 1 to 3 d after operation, blood WBC exceeding 15.0× 109/L in 15 cases (93.8%), gallbladder tumefaction and double layer structure by B mode ultrasound, the diagnostic accuracy before operations was 81.3 %. We performed cholecystectomy in 10 cases, cholecystectomy and choledochotomy for common bile duct exploration and stone removal and T-tube drainage in 2, partial cholecystectomy in 3, cholecystostomy in 1. Pathological examination showedthat it was AGC in all the patients. Conclusion Latency in 1 to 3 d, local pertonitis, high blood WBC and B mode ultrasound are main managements in diagnosis of AGC and it should be diagnosed carefully distinguished from perforation and severe acute pencreatitis. It is suggested to undergoing early surgi-cal management once diagnosed definitely.
8.Study on Method of Quality Control for Zhilining Pill
Dehua LI ; Fangjin LU ; Yan NI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(03):-
Objective To establish the quality standard for Zhilining pill. Methods TLC was employed to identify Radix Sophorae Flavescentis and Radix Aucklandiae while the content of dehydroandrographolide in Zhilining pill was detemined by HPLC. Results TLC findings of Radix Sophorae Flavescentis and Radix Aucklandiae showed the spots of same colors as those developed in the corresponding places of control medical materials. Good liner was observed when the samplesize of dehydroandrographolide was within the range of 0.062~1.550 ?g (r =1.000 0). The average recovery rate was 98.00% with RSD=0.90%. Conclusion The method is simple, accurate, stable, reliable and with good reproducibility, which can be used for the quality control of Zhilining pill.
9.Study on Chemical Constituents in Crepis Turczanilwii
Yan NI ; Fangjin LU ; Xuliang HAO
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(04):-
Objective To study the chemical constituents in Crepis turczaniowii C. A. Mey. Method The constituents were isolated and purified by column silica,polystyrene resin RA and polyamide columbine chromatography,and the structures were identified by physicochemical data,MS and NMR. Result Two compounds were obtained in the Petroleum ether fractions as ?-taraxasteryl acetate (Ⅰ) and ?-sitosterol (Ⅱ),and one compound was obtained in the n-BuOH fractions as phillyrin (Ⅲ). Conclusion All above compounds are obtained from the plants of Crepis turczaniowii C. A. Mey. for the first time. Ⅲ is isolated from Crepis L. for the first time.
10.Diagnostic value of MSCTU in ureterovesical junction diseases
Fangqing GE ; Jingui LU ; Weibing NI
Journal of Practical Radiology 2015;(5):802-804,809
Objective To explore the value of MSCTU in ureterovesical junction diseases.Methods MSCTU data in 41 patients with different diseases in ureterovesical junction were retrospectively analyzed.All patients underwent plain and triphase contrast en-hanced CT scans.The primary imaging data were transmitted to a worksation to get the maximum intensity projection (MIP),vol-ume rendering (VR),multiplanar reconstruction (MPR)and curve plannar reconstruction (CPR)images.Results (1)CT showed congenital abnormality in 7 patients including ectopic ureteral orifice in 1,megaloureter in 1,duplication of the urter in 4 and uret-erocele in 2.(2)Urinary stone in 25 with bladder filling defect in 1 1.(3)Tumor in 9 including polyp in 1,urothelial carcinoma in 6 and prostate cancer in 2.MSCTU clearly showed the location,shape,size of the ureterovesical junction diseases and the relationship with surrounding structures.Conclusion MSCTU plays an important role in diagnosis of ureterovesical junction diseases with an ac-curate rate of 97.5%(40/41).