Objective To explore the clinical significance of serum total bile acid (TBA) test in evaluation of the prognosis of posthepatitis cirrhosis.Methods 92 patients with posthepatitis cirrhosis were selected as the observation group,and divided into A,B,C groups according to the Child-Pugh grades.32 healthy people were selected as the control group.The level of serum TBA was detected and compared.Results The level of TBA in the observation group was (84.26 ±49.03) μmol/L,which was higher than that in the control group[(3.52 ± 2.67) μmol/L](t =17.53,P ＜ 0.01).The level of TBA was gradually increased in Child-Pugh grade A,B,C grade,and the differences were statistically significant (t =3.84,6.21,5.49,all P ＜ 0.05).Conclusion TBA test is benefit for the diagnosis and prognosis of posthepatitis cirrhosis.

OBJECTIVE:To evaluate the effect of pharmaceutical care (PC) program on hypotension. METHODS: The pertinent literature from January 1999 to February 2008 was retrieved from Medline, EMBASE, Cochrane, CNKI, CBM and other databases, and the randomized controlled trials (RCTs) with the intervention measures of PC were collected. The literature retrieving and screening were done respectively by 2 statistical clerks. A meta-analysis of the data was conducted by using the Review Manager 4.2 software. RESULTS: A total of 5 RCTs with 585 hypertension patients were included in this Meta analysis. Compared with the control group, the PC program intervention group had significantly lower systolic blood pressure (SBP) and diastolic blood pressure (DBP) after follow-up; and the SBP and DBP had a much better improvement in the intervention group than in the control group. CONCLUSION: The high blood pressure can be effectively controlled by carrying out the PC program such as medication consultation and health education etc in hypertensive patients.

Radiofrequency thermocoagulation technique,as a maturity procedure,has been used routinely for trigeminal neuralgia.Radiofrequency thermocoagulation has high rates of pain relief,a long duration of pain relief,and few serious perioperative complications.This technique very suits for old patients or patients with cardiovascular diseases.The common complications include numbness,absence of corneal reflex,and master weakness.Keratitis,dysesthesia and dolorosa greatly affect patients’ quality of life.Radiofrequency thermocoagulation is an effective and promising method in the treatment of trigeminal neuralgia.Practitioner should pay attention to pain relief and reducing complications and this will help to improve their quality of life.

Objective To improve the treatment level of serous otitis media(SOM)in children.Methods 56 patients were treated by positive pressure tympanic administration of ?-Chymotrypsin and Triamcinolone Acetonide through auripuncture into a single hole and 55 cases by myringotomy with grommet insertion.Results The total effective rate of serous otitis media by positive pressure tympanic administration through auripuncture into a single hole and by myringotomy with grommet insertion was 89.8%,90.8% respectively.But the former obviously had more advantages over the latter.Conclusion The technique is better in that it is safe,painless,economical,and non-traumatic.It is an effective method in treating serous otitis media in children.

Aconitum ; Drugs, Chinese Herbal ; pharmacology ; therapeutic use ; Humans ; Kidney Diseases ; drug therapy ; Medicine, Chinese Traditional ; Rhizome

Objective To elucidate that AIDS is not equal to any disease of TCM. Methods Previous literatures on differentiating the difference between AIDS and its similar TCM termed diseases as "Fuqiwenbing", "Wendu", and "Xulao" were reviewed and further discussion on the differences was performed by the author. Results Many scholars draw a conclusion that AIDS is not equal to any of TCM diseases or syndromes by their detailed research, comparison and analysis. Conclusion AIDS is not any of TCM termed disease, but it can be treated with the successful experience of TCM in treating other traditional diseases.

Objective To observe the clinical efficacy and safety of etoposide capsule (VP16) in the treatment of recurrent small cell lung cancer. Methods Retrospective analysis 39 patients,aged≥65, with relapsed small cell lung cancer, who were at least three months after the end of the first-line treatment since January 2012 to January 2014 in Tianjin fifth central hospital.Etoposide was administered by daily oral at 100 mg/day for seven consecutive days and withdraw for 14 days,21 days as a therapeutic cycle,repeat treatment until disease progression or intolerable side effects occur, analyze the progression-free survival and overall survival.Observe the clinical benefit rate,the overall response rate and safety.Results The clinical benefit rate (DCR) and overall response rate (ORR) after the treatment were 61.5% and 30.77%.The progression-free survival (PFS) was 2.8 months, and the overall survival (OS) was 7.3 months.Neutropenia is the most common toxicities, and grade Ⅲ or Ⅳ occurred in 7.7% of the patients.No grade Ⅲ or Ⅳ thrombocytopenia, or grade Ⅲ or Ⅳ non-hematologic toxicity was occured.Conclusion Etoposide oral capsules monotherapy may be considered as one of the safe and effective choice of the second-line treatment of elderly patients with relapsed small cell lung cancer.

OBJECTIVE: To explore approaches for further development of pharmaceutical care in retail drugstores by strengthening drug administration. METHODS: The main problems occurred in pharmaceutical care were analyzed from the perspective of drug administration. RESULTS & CONCLUSIONS: The main problems occurred in pharmaceutical care were the absence of laws and regulations related to pharmaceutical care,misalignment between the access criteria for retail pharmacy and the necessary conditions for pharmaceutical care. The development of pharmaceutical care could be promoted by perfecting current law system,enhancing the access criteria for running retail drugstore,and strengthening drug administration etc.

Purpose:To investigate the mechanisms,susceptibility,prevention and treatment of the tumor patients'renal function,which was injured by the Body Gama Kinfe treatment.Methods:There were 7 patients,who had been observed for the effect of hydration,vaso-dilation,diuresis,basifying urine,anti-coagulation,detocifiation,even hemodialysis.Results:All patients' renal function gradually recovered.Conclusions:The tumour patients' renal function can be acutely injured by Body Gama Kinfe treatment.The patients who were elderly or inherent in renal failure would be prone to injary.In general we could improve the situation by better prevention,early-diagnosis,efficient treatment,so that we can not only alleviate the injuries,but also speed recovery,thus achieving better prognosis.

Objective To evaluate the association between cytomegalovirus (HCMV) infection and atherosclerosis (AS) and explore the possible role of endothelin (ET) and serum tumor necrosis factor(TNF ?) in the pathogenesis of AS in diabetic patients and the relationship between HCMV infection and concentrations of ET and TNF ?. Methods Blood samples were collected from 21 patients with AS of type 2 DM, 47 patients with non AS of type 2 DM and 20 controls. Special antibodies to HCMV (IgM,IgG) were measured by enzyme linked immunosorbent assay (ELISA) . The concentrations of serum TNF ? and plasma ET were determined by RIA. Results (1) Type 2 diabetic patients, especially those with established AS, had a higher prevalence of active infection of HCMV. (2) The levels of plasma ET and serum TNF ? in type 2 diabetic patients were higher than those in normal people. In the pathogenesis of AS in diabetic patients, the ET played more important role than the TNF ?.(3) There was a significantly positive correlation between anti IgM to HCMV and the level of plasma ET in type 2 DM patients. It suggested that the injury of endothelium cell was related to the active infection of HCMV. Conclusion The study suggests that HCMV infection may be important in the pathogenesis of AS in type 2 diabetic patients and ET possibly plays an important role on the pathological course of AS.