Primitive neuroectodermal tumors (PNETs) are a heterogeneous group of malignant neoplasms found primarily in childhood and early adulthood. In this paper, we described the case of a 64-year-old male with primary spinal PNET, successfully treated with surgery, craniospinal radiotherapy, and concurrent chemotherapy. This is the case of a 64-year-old male who presented with a 2-month history of bilateral lower extremity weakness and numbness associated with urinary and bowel incontinence. Work-up was done, and the spine's plain magnetic resonance imaging (MRI) revealed a heterogeneously enhancing intradural lesion with an extradural component at the right T9/T10 level, causing mild to moderate cord compression. The patient underwent laminectomy and gross total resection of the said tumor. Histology and immunohistochemistry were consistent with a primitive neuroectodermal tumor of the spine. The tumor recurred three months after the surgery, and the patient was then referred for radiation therapy with concurrent chemotherapy. Repeat spinal MRIs with three- to six-month intervals after treatment showed no tumor recurrence as of August 2021. Primary spinal PNETs are rarely found in adults, especially in the elderly. These tumors currently have no recommendations or guidelines regarding their management. Thus, most cases are presently being managed based on studies on children and central nervous system (CNS) PNETs. This paper presented a case of a successfully treated primary spinal PNET in the elderly. The management was primarily based on studies done on that of the pediatric population and CNS PNETs.
Neuroectodermal Tumors, Primitive ; Neuroectodermal Tumors, Primitive, Peripheral

No abstract available.
Kidney* ; Neuroectodermal Tumors, Primitive*

No abstract available.
Neuroectodermal Tumors, Primitive*

No abstract available.
Neuroectodermal Tumors, Primitive, Peripheral*

No abstract available.
Drug Therapy* ; Neuroectodermal Tumors, Primitive*

Trilateral retinoblastoma is a syndrome involving midline intracranial malignancies in children with the heritable form of retinoblastoma. It is rare and usually lethal in spite of aggressive treatments. We report a case of trilateral retinoblastoma with review of the literature to gain further insight into this uncommon disease.
Child ; Humans ; Neuroectodermal Tumors, Primitive ; Retinoblastoma*

Extraskeletal Ewing' sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the osseous Ewing's sarcoma (ES). We report a case of recurrent EES of the breast that, to the best of our knowledge, has rarely been reported. It was initially confused for a cyst on ultrasound. In addition, MRI and breast-specific gamma imaging (BSGI) in our case have complementary value over conventional imaging.
Breast ; Neuroectodermal Tumors, Primitive ; Sarcoma ; Sarcoma, Ewing

The authors presented one case of Dysembryoplastic neuroepithelial tumor revealed at a 23 years old woman with a 6 years epileptic. The histological and immunohistochemical aspect identified a “nonspecific” DNT. The authors discussed about the clinical, CT scanner, MRI and pathologic aspects and reviewed in literature
Neuroectodermal Tumors, Primitive, Peripheral ; Neoplasms, Neuroepithelial

Atypical teratoid/rhabdoid tumor rarely occurs in the CNS, though is most common in infants under two years of age. It is characterized by unique histologic features, has an extremely aggressive natural course, and is located mainly in the infratentorial region. Radiologically, it is difficult to distinguish from primitive neuroectodermal tumor or medulloblastoma. We report the radiologic findings of two cases of atypical teratoid/rhabdoid tumor.
Humans ; Infant ; Medulloblastoma ; Neuroectodermal Tumors, Primitive

No abstract available.
Neuroectodermal Tumors, Primitive, Peripheral* ; Ulnar Nerve*