1.Change in plasma glucose, cholesterol, triglyceris cortisol, catecholamin levels in the elderly suffered from blood hypertension and the elderly diagnosed to be neurasthenia training the traditional relaxation method
Journal of Vietnamese Medicine 2003;282(3):23-30
The study carried on 143 patients at 60 to 75 years old devide into 2 groups: the research include 100 people (50 high pressure, 50 nervous depression) practise tradition relax and control group with 43 people (22 high pressure, 21 nervous depression) didn’t practise tradition relax. All subjects were test glucoza, cholessterol, triglycerid, catecholamin, cortisol. High pressure group was measured vessel pressure index. Result: Practising tradition relax reduce glucoza, cholessterol, catecholamin, serum cortisol level in elderly people with nervous depression and high pressure. Vessel, pressure after 30minutes and 8 week of practising reduce compare with before pratising. Meanwhile in control group, vessel and pressure change indignificant
Hypertension
;
blood
;
Neurasthenia
2.Neurotic characteristics in headache patients.
Journal of the Korean Academy of Family Medicine 1998;19(9):728-735
BACKGROUND: Headache is one of the most common medical complaints. The majority of headaches are not associated with significant organic disease. Many persons are susceptible to headaches at times of emotional or physical distresses. The purpose of this study is to evaluate neurotic symptoms of headache patients. METHODS: The present study was made in the patients with headache symptoms. who had visits t,he outpatient clinic of Family Medicine of a University Hospital from April 1st to July 31st, 1996, 110 subjects with headaches and 136 controls which were closely matched according to sex, age and socioeconomic status. Neurotic symptoms were assessed using the Symptom Check List for Minor Psychiatric Disorders(SCL-MPD). The statistical analysis was made between the two groups. RESULTS: 1) All but 3 items were significantly higher in headache group(p<0.05 : 2 items;p<0.01 : 9 items ; p<0.001 : 53 items). 2) The headache group had a statistically significant higher score of the each neurotic dimension in comparison of the non-headache group (somatization, anxiety, depression , anger-hostility, interpersonal -sensitivity, phobic anxiety, obsessive -compulsive , neurasthenia, hypochondriasis and general) (p<0.001). 3) The age and the presence of occupation were significantly associated with headache symptoms. The somatization and depression scales had the strongest independent association with headaches as compared with other dimensions. CONCLUSIONS: Persons with headache had higher levels of neurotic symptoms and psychological distresses compared to the non-headache group. Physicians need to be aware of the various types of distresses comprehensively with psychosocial assessments and evaluations.
Ambulatory Care Facilities
;
Anxiety
;
Depression
;
Headache*
;
Humans
;
Hypochondriasis
;
Neurasthenia
;
Occupations
;
Social Class
;
Weights and Measures
3.Professor McLaren (2). His Theories of Psychiatry.
Journal of Korean Neuropsychiatric Association 2012;51(1):25-35
Professor Dr. Charles I. McLaren (1882-1957) of the Department of Psychiatry, Severance Union School of Medicine in Seoul, Korea had introduced not only Christianity but medicine and psychiatry of his time with his own theories to Korea while he had served as a Christian missionary from Australia to Korea from 1911 to 1941. Based on his view of Christianity and knowledge of modern science and medicine, he tried to explore the etiology, symptoms, treatment and spiritual meaning of mental disorders including general paresis, dementia praecox, mania, melancholia, paranoia, neurasthnenia, hysteria, hypochondriasis, and even psychophysiological disorder. Though he accepted that mental disorders are related to disrupted functions of brain or neurons, he believed that fundamental causes of insanity is spiritual. Regarding etiology, he suggested that people's choice not to follow God's logos by their free-will and consequent disharmony with nature or human society or failure of self to adapt to reality causes mental disorders. And he explained psychotic phenomena in view of Christian spirituality. In addition, he argued "psychic" (psychological or spiritual) conflict, sensitivity and guilt feeling as a possible etiology of psycho-neurosis including neurasthenia, hysteria and hypochondria. Conflict includes not only sexual conflicts but social conflicts related to family, job, money, or guilt feeling. He also emphasized the meaning and purpose of life in relation to development of mental illness. Remarkably, he introduced idea of "spill-over" to explain how emotional problems influence autonomic dysfunction resulting in psycho- physiological symptoms. He can be recognized as a psychiatrist who integrated bio-medical descriptive psychiatry with psycho-social approach, dynamic psychotherapy and even spiritual approach as a fundamental one. Though many scientific criticism can be given to his theories of psychaitry, he is deserved to be rediscovered and recognized as a pioneer who had shown another apprach to mental disorders to present psychiatrists who are lost in confusion with so many uncertainties in regard to understanding and treating mental disorders.
Australia
;
Bipolar Disorder
;
Brain
;
Christianity
;
Depressive Disorder
;
Guilt
;
Humans
;
Hypochondriasis
;
Hysteria
;
Korea
;
Mental Disorders
;
Missions and Missionaries
;
Neurasthenia
;
Neurons
;
Neurosyphilis
;
Paranoid Disorders
;
Psychiatry
;
Psychophysiologic Disorders
;
Psychotherapy
;
Schizophrenia
;
Spirituality
4.The negative psychology for the public in Zhejiang province during the epidemic of human H7N9 avian influenza.
Renjie ZHANG ; Tingting JIANG ; Na LI ; Zhen WANG ; Biyao LIU ; Le FANG ; Xinwei ZHANG
Chinese Journal of Preventive Medicine 2015;49(12):1073-1079
OBJECTIVETo evaluate the cognition and emotional response of the public in Zhejiang province during the epidemic of human H7N9 avian influenza and provide scientific support for group psychological intervention under public health emergency.
METHODS57 communities in 19 counties from Hangzhou, Jiaxing and Lishui district of Zhejiang province were selected as survey sites using stratified clustered sampling method from March, 2013 to April, 2014. 2 319 ordinary civilians were chosen using convenience sampling method and 390 individuals who had close contact history with H7N9 avian influenza patients, 109 family members of patients and 281 medical workers, were selected using census method. The inclusion criteria for subjects were: subjects aged over 10 years; could complete the questionnaire independently or with the help of the investigators. A total of 2 709 subjects were surveyed by avian influenza risk perception and response questionnaire, negative emotion questionnaire was also used to see their cognition and negative emotion related to the disease. Spearman correlation analysis was used to analyze the interrelationship between public risk perception, response and negative emotions.
RESULTS95.10% (2 576)of the subjects have sensed the risk of epidemic and 91.00% (2 465) of the subjects have taken preventive measures in 2 709 subjects. The positive rate for depression, neurasthenia, fear, anxiety and hypochondriasis were 36.40% (986) , 37.21% (1 008) , 79.70% (2 159) , 33.41% (905) , 27.69% (750) respectively (χ(2)=1 935.89, P<0.001) ;the P(50)(P(25)-P(75)) of the depression scores of patients' family members, medical workers and the general public were 0.50 (0.00-0.83), 0.17 (0.00-0.67), 0.17 (0.00-0.50) (H= 7.27, P=0.03) ; the neurasthenia scores were 0.20 (0.00-0.60), 0.2 (0.00-0.40), 0.00 (0.00-0.20) (H= 64.74, P<0.001) ; fear scores were 0.83 (0.33-1.17), 0.33 (0.17-0.67), 0.33 (0.17-0.83) (H=30.03, P< 0.001) ; anxiety scores were 0.17(0.00-0.50), 0.00(0.00-0.33), 0.00(0.00-0.17) (H=51.82, P<0.001). The neurasthenia, fear, anxiety scores (P(50)(P(25)-P(75))) for females among the public were 0.00(0.00-0.20), 0.50(0.17-0.83), 0.00(0.00-0.17), which were higher than those of male's (0.00(0.00-0.20), 0.33(0.00-0.67), 0.00(0.00-0.17)) (χ(2) values were 5.26, 27.52, 8.29, P<0.05); Among medical staff, the depression, neurasthenia, fear, anxiety and hypochondriasis scores for females were 0.33(0.00-0.67), 0.20(0.00-0.40), 0.50(0.17-0.83), 0.00(0.00-0.33), 0.00(0.00-0.50) respectively, which were higher than those of males'(0.00(0.00-0.50), 0.00(0.00-0.40), 0.33(0.17-0.50), 0.00(0.00-0.17), 0.00(0.00-0.00))(χ(2) values were 7.22, 7.97, 14.46, 4.93, 5.22, P<0.05); for the family members of the patients who were in poor mental conditions when doing self-assessment, their depression and neurasthenia scores were 0.50(0.08-0.96), 0.30(0.00-0.55), which were higher than those of people in good mental conditions (0.17(0.00-0.83), 0.20(0.00-0.60)) (χ(2) values were 12.95, 11.20, P<0.05). Spearman correlation analysis showed that the subjects' risk perception level was positively correlated with depression, neurasthenia, fear, and hypochondriasis, with the correlation coefficients 0.07, 0.07, 0.08, 0.04, respectively (P<0.05) ; the subjects' risk response level was also positively related with depression, neurasthenia, fear, anxiety and hypochondriasis, and the correlation coefficients were 0.09, 0.09, 0.12, 0.05, 0.04, respectively (P<0.05).
CONCLUSIONThe general public was highly concerned about the epidemic of H7N9 avian influenza and developed certain levels of negative emotions. The female, equal or over 60 years old, those with poor educational level, agricultural related occupation and poor physical and psychology health were risk factors of disease related negative emotions. The subject's risk perception and response level was positively related with depression, neurasthenia, fear and hypochondriasis.
Anxiety ; China ; Depression ; Epidemics ; Family ; Fear ; Female ; Humans ; Hypochondriasis ; Influenza A Virus, H7N9 Subtype ; Influenza, Human ; psychology ; Male ; Neurasthenia ; Occupations ; Risk Factors ; Surveys and Questionnaires
5.Phenolic acids isolated from the fungus Schizophyllum commune exert analgesic activity by inhibiting voltage-gated sodium channels.
Hui-Min YAO ; Gan WANG ; Ya-Ping LIU ; Ming-Qiang RONG ; Chuan-Bin SHEN ; Xiu-Wen YAN ; Xiao-Dong LUO ; Ren LAI
Chinese Journal of Natural Medicines (English Ed.) 2016;14(9):661-670
The present study was designed to search for compounds with analgesic activity from the Schizophyllum commune (SC), which is widely consumed as edible and medicinal mushroom world. Thin layer chromatography (TLC), tosilica gel column chromatography, sephadex LH 20, and reverse-phase high performance liquid chromatography (RP-HPLC) were used to isolate and purify compounds from SC. Structural analysis of the isolated compounds was based on nuclear magnetic resonance (NMR). The effects of these compounds on voltage-gated sodium (NaV) channels were evaluated using patch clamp. The analgesic activity of these compounds was tested in two types of mouse pain models induced by noxious chemicals. Five phenolic acids identified from SC extracts in the present study included vanillic acid, m-hydroxybenzoic acid, o-hydroxybenzeneacetic acid, 3-hydroxy-5-methybenzoic acid, and p-hydroxybenzoic acid. They inhibited the activity of both tetrodotoxin-resistant (TTX-r) and tetrodotoxin-sensitive (TTX-s) NaV channels. All the compounds showed low selectivity on NaV channel subtypes. After intraperitoneal injection, three compounds of these compounds exerted analgesic activity in mice. In conclusion, phenolic acids identified in SC demonstrated analgesic activity, facilitating the mechanistic studies of SC in the treatment of neurasthenia.
Analgesics
;
administration & dosage
;
chemistry
;
isolation & purification
;
Animals
;
Humans
;
Hydroxybenzoates
;
administration & dosage
;
chemistry
;
isolation & purification
;
Mice
;
Neurasthenia
;
drug therapy
;
genetics
;
metabolism
;
Schizophyllum
;
chemistry
;
Voltage-Gated Sodium Channel Blockers
;
administration & dosage
;
chemistry
;
isolation & purification
;
Voltage-Gated Sodium Channels
;
genetics
;
metabolism
6.Research by Psychiatrists of Chosun Chongdokbu Hospital and Keijo Imperial University in Korea during Japanese Colonial Rule.
Sung Kil MIN ; Chang Ho LEE ; Kyubak LEE
Journal of Korean Neuropsychiatric Association 2015;54(2):142-171
Eighty-three of 114 original articles and abstracts of research published by neuropsychiatrists of Chosun Chongdokbu Hospital (the Japanese colonial government hospital in Korea) and Keijo (Seoul) Imperial University Hospital during the Japanese colonial period (1910-1945) in journals including Shinkeigaku-zassi (Neurologia), Seishin-shinkei-gaku zassi (Psychiatria Et Neurologia Japonica), and The Journal of Chosun (Korea) Medical Association were reviewed. Most articles were on clinical research based on descriptive and biological psychiatry while only 4 articles were on dynamic psychiatry, probably because Japanese pioneers in psychiatry had introduced German psychiatry into Japan during the 1880s. The first paper was written by Dr. Shim Ho-sub. Professor Kubo of Keijo (Seoul) Imperial University published most articles, followed by Dr. Hikari, Dr. Hattori, and Dr. Sugihara. There were more articles on symptomatic psychosis and morphine addiction, followed by general paralysis, schizophrenia, neurological diseases, narcolepsy, epilepsy, and neurasthenia. The meaningful articles even for today were comparative studies between Japanese and Koreans and articles on opioid use disorder in Korea. Authors reported a markedly lower rate of psychotic inpatients in the population of Koreans compared with Japanese. Japanese researchers argued that, because of simpleness in social life in Korea and less violence or excitement in symptoms, Korean mental patients could be cared for by family or members of the community, or be treated by shamanism rather than bringing them to a public mental hospital, and poverty also prohibited hospital care. Finding of higher ratio of schizophrenia to manic-depressive psychosis among Koreans than Japanese was discussed in relation to delayed cultural development of Korea compared to Japan. In addition, traditional customs prohibiting marriage between relatives in Korea was related to low prevalence of manic-depressive psychosis, local endemic malaria was related to low prevalence of general paresis, and poor general hygiene was related to high prevalence of epilepsy. Unclear (undifferentiated) form of psychotic symptoms including hallucination and delusion was reported in more Koreans than Japanese. Also Korean patients showed a more atypical form in diagnosis. Authors added that they had found no culture-specific mental illness in Korea. However, no Korean psychiatrists were included as author in such comparative studies. Comparative studies on constitution between Koreans and Japanese mental patients and prisoners were also unique. However, no Korean psychiatrists participated in such comparative studies. In studies on morphine addiction in Koreans, Japanese researchers argued that such studies were necessary to prevent introduction of morphine-related criminal phenomena to Japan. Meanwhile, Dr. Kubo had left a notion on adaptation problems of Japanese living in the foreign country, Korea. Nevertheless he reported nothing about psychosocial aspects of mental illness in relation to political, cultural, and economic difficulties Koreans were experiencing under the colonial rule of Japan. These general trends of studies based on German biological and descriptive psychiatry and policies of colonial government to isolate "dangerous" mental patients in hospital appeared to reflect colonial or ethnopsychiatry of those days. These policy and research trends seem to have worsened stigma attached to mental disorders. Japanese tradition of psychiatric research was discontinued by return home of Japanese scholars with the end of WWII and colonial rule.
Asian Continental Ancestry Group*
;
Biological Psychiatry
;
Bipolar Disorder
;
Constitution and Bylaws
;
Criminals
;
Delusions
;
Diagnosis
;
Epilepsy
;
Ethnopsychology
;
Hallucinations
;
Hospitals, Psychiatric
;
Humans
;
Hygiene
;
Inpatients
;
Japan
;
Korea
;
Malaria
;
Marriage
;
Mental Disorders
;
Mentally Ill Persons
;
Morphine Dependence
;
Narcolepsy
;
Neurasthenia
;
Neuropsychiatry
;
Neurosyphilis
;
Poverty
;
Prevalence
;
Prisoners
;
Prisons
;
Psychiatry*
;
Psychotic Disorders
;
Schizophrenia
;
Shamanism
;
Violence
7.The Analysis of Research Trend about Management of Low Back Pain.
Korean Journal of Rehabilitation Nursing 1998;1(1):51-60
The result of studying papers about management of lower back pain published in domestic and foreign nursing and medical magazines in these 10 years is as follows; 1. General characteristic of lower back pain; 1) In sex distribution, there were more men than women in 5 papers and more women than men in 4 papers among 9 papers surveryed. 2) In age distribution, thirties to forties of patients had more lower back pain as surveyed by general hospitals and fifties to sixties of patients had more lower back pain as surveyed by oriental medical hospitals. 3) In cause factor, there were 50 to 65% of sprain, 32 to 44% of herniated intervertebral disc and 13 to 29% of degenerative changes. 4) In symtom distribution, there were 26 to 57% of lower back pain, 42 to 65% of lower back pain with radiating pain and 34 to 99% of paravertevral muscle spasm. 5) In period of pain management distribution, 18 to 40% of patients experienced pain for Jess than 6 months and 59 to 82% of them experienced pain for more than 6 months in 3 papers among 4 papers. 6) In surveying the treatment, 66 to 88% of patients had conservative treatment and there were treatments of general hospital, oriental medicine, self remedy and traditional practice in conservative treatment. 7) In job distribution, 12 to 50% of them were housekeepers, 23 to 31% office workers, 4.6 to 36% blue color workers and 11 to 15% students. 2. As psychological character lower back pain paients had anxiety, depression, anger-hostility, phobic anxiety, neurasthenia, hypochondriasis, and interpersonal sensitivity. 3. To distinguish the cause of lower back pain, plain lumbar roentgenogram, straight leg rasing test, eletromyelogic findings, somatosensory evoked potentials CT and MRI were performed. 4. To relieve lower back pain, epidural adhesiolysis, epidulal injection of local anesthetic in mixture with steroid, lumbar spinal root block, low level laser therapy, acupuncture like transcutaneous nerve stimulation(ALTENS), topical capsaicin and lumbar orthotics were used in medical field, and relaxation technique was used in nursing field. 5. Mckenzie's extension exercise and William's flexsion exercise for lower back pain were used in medical field and Yoga exercise was applied in nursing field. 6. The more school education and self efficacy were high, the better they had active coping lower back pain positively and the less self efficacy was the more they had serious pain. As a result of studying the paper there have been very little research for lower back pain in nursing fields of Korea and foreign countries. Because 60 to 80% of population expeience lower back pain at least more than once, it is necessary to develop the study and clinical practice for management of lower back pain.
Acupuncture
;
Age Distribution
;
Anxiety
;
Capsaicin
;
Depression
;
Education
;
Evoked Potentials, Somatosensory
;
Female
;
Hospitals, General
;
Humans
;
Hypochondriasis
;
Intervertebral Disc
;
Korea
;
Low-Level Light Therapy
;
Leg
;
Low Back Pain*
;
Magnetic Resonance Imaging
;
Male
;
Medicine, East Asian Traditional
;
Neurasthenia
;
Nursing
;
Pain Management
;
Periodicals as Topic
;
Relaxation
;
Self Efficacy
;
Sex Distribution
;
Spasm
;
Spinal Nerve Roots
;
Sprains and Strains
;
Yoga