Objective To explore the effect of continuity education by WeChat public information platform on health education to advanced lung cancer patients undergoing treatment by implanting 125 1 radioactive particles guided by CT after discharge.Methods During August 2014 and August 2015,60 patients with advanced lung cancer admitted into the department of oncology of 3 military hospitals in Fujian Province were equally divided into control group and observation group by a simple random sampling method:the control group was given conventional discharge education and the observation group was treated continuity care by way of follow-up WeChat public information platform for more than 4 times for each patient.The two groups were compared in terms of physical function,satisfaction and rate of complications 6 months after discharge.Results The physical function of the observation group was significantly improved as compared to that the control group (P ＜ 0.05).The satisfaction level was significantly improved as well (P ＜0.05).The rate of complications in experient group was less statistically significant (P ＜ 0.05).Conclusion Continuity nursing with Watchat can prevent the occurrence of complications,relieve the pains of patients and improve patients' medical compliance as well as the quality of life.

Objective To investigate the effect of night shift time at midnight on sleep quality of nurses . Methods Pittsburgh sleep quality index (PSQI) and a self-designed questionnaire were used for the investigation among 459 nurses in a first class hospital in Fujian Province, analyzing the sleep quality of the nurses at night shift time at the time points of 0:00am,0:30am,1:00am and 1:30am during the midnight. Results The total score of nurses at night shift was (7.47 ±3.05). There were significant differences between the total scores at different time points (P<0.001). The comparisons between the time points of 0:00am and 0:30am,0:30am and 1:00am, 0:00am and 1:00am showed significant differences (P<0.017),and 0:00am<0:30am<1:00am. Conclusions As for night shift during midnight, the sleep quality for the night shift time 0:00am>0:30am>1:00am. The time points for night shift can vary with seasons and regions. The nurses should be aware of occupational prevention and develop a living habit. During night shift, the nurses should make an individualized plan.

Objective:To explore the effect of homemade aromatic masks on nausea, vomiting and pain in non-small cell lung cancer patients with chemotherapy.Methods:From October 2018 to August 2019, convenience sampling was used to select 82 patients with non-small cell lung cancer admitted to the 900th Joint Logistic Support Unit of the People's Liberation Army of China. All patients were randomly divided into control group and experimental group, each with 41 cases. Control group carried out the routine care, and experimental group was treated with the homemade aromatic mask on this basis. The Chinese version of Index of Nausea and Vomiting and Retching (INVR) and the Brief Pain Index (BPI) were used to compare nausea, vomiting and pain indicators of patients between two groups during chemotherapy.Results:On the third day of chemotherapy, the total score of nausea and vomiting, and the average pain score of experimental group were (11.00±5.46) and (1.63±1.14) respectively, lower than those of control group, and the differences were statistically significant ( t=-6.635, -4.781; P<0.01) . Conclusions:The homemade aromatic mask can relieve chemotherapy-induced nausea and vomiting in non-small cell lung cancer patients with chemotherapy, and reduce the pain of patients.

OBJECTIVETo understand the incidence of central obesity and its characteristics, and explore the effects of lifestyle factors on incidence of central obesity in Chinese adults aged 35-74 years.

METHODSA total of 27 020 Chinese adults aged 35 to 74 years were enrolled in a prospective follow-up study (the study cohort was built from 1998 to 2000, respectively) during 2007 and 2008. Central obesity was defined as waist circumference ≥ 90 cm in men, ≥ 85 cm and ≥ 80 cm in women, respectively. Multivariate logistic regression was used to estimate relative risks (RR) of central obesity for lifestyle factors after adjusting factors including genders, age, southern and geographic region, urbanization, lifestyles, and so on.

RESULTSAmong Chinese adults aged 35-74 years, the standardized annual incidence of central obesity (waist ≥ 90 cm) was 2.19% for men and this rate decreased gradually with age among people younger than 65 years old. The incidence of central obesity was 2.64% (waist ≥ 85 cm) and 4.06% (waist ≥ 80 cm) for women, respectively, and this rate increased obviously among people aged 55 to 74 years. Participants with ≥ 12 years' education (RR = 0.84, 95%CI:0.74-0.96) had a lower risk of central obesity(waist ≥ 90 cm for men, waist ≥ 85 cm for women). And this risk increased as the monthly household per capita income increased. Compared with the reference group, people involved in housework or retirees (RR = 1.17; 95% CI: 1.01-1.36), drinking alcohol (RR = 1.15, 95% CI: 1.01-1.32) or scented tea (RR = 1.49, 95%CI:1.28-1.72) had a higher risk of developing central obesity, while drinking milk (RR = 0.85, 95% CI: 0.74-0.97) or black tea (RR = 0.74, 95% CI: 0.58-0.95), had a lower risk of developing central obesity.

CONCLUSIONA healthy lifestyle plays a key role in the prevention and control of central obesity in Chinese adults, and a healthy way of lifestyle should be promoted in the whole society to decelerate the epidemic of the central obesity.

Adult ; Aged ; Alcohol Drinking ; Animals ; Body Mass Index ; China ; epidemiology ; Demography ; Female ; Follow-Up Studies ; Humans ; Incidence ; Life Style ; Logistic Models ; Male ; Middle Aged ; Milk ; Obesity, Abdominal ; Prospective Studies ; Risk Factors ; Socioeconomic Factors ; Tea ; Waist Circumference

Objective: To evaluate the effectiveness of eradication therapy based on Helicobacter pylori (Hp) susceptibility and CYP2C19 genotype in children with refractory Hp infection. Methods: In this prospective observational cohort study, 156 children with Hp refractory to amoxicillin+clarithromycin+omeprazole triple regimen in Baoding Children′s Hospital from December 2017 to May 2018 were enrolled. Ninety-two of them underwent Hp culture and CYP2C19 detection. Seventy-five cases with positive Hp culture were defined as culture successful group and were treated according to Hp susceptibility and CYP2C19 genotype. Seventeen cases with negative Hp culture were defined as culture failed group and were treated only based on the results of CYP2C19 genotype. Sixty-four children who did not have Hp culture and CYP2C19 gene testing were defined as the empirical eradication therapy group and were treated with quadruple regimen (amoxicillin+metronidazole+omeprazole+bismuth). Bacterial resistance, CYP2C19 polymorphism and therapeutic effectiveness between the three groups were compared using chi-square test. Results: Among the 75 positive Hp culture results, 72 (96%) were resistant to clarithromycin, 3 (4%) were resistant to metronidazole, 5 (7%) were resistant to levofloxacin, 5 (7%) were resistant to rifampicin, 1 (1%) was resistant to tetracycline, and none was resistant to amoxicillin and furazolidone. The CYP2C19 polymorphism in 92 patients showed that 43 (47%) were extensive metabolizer (EM), 9 (10%) were poor metabolizer (PM), and 40 (43%) were intermediate metabolizer (IM). In terms of the effectiveness, eradication rate in the culture successful group,culture failed group and empirical eradication therapy group were 99% (74/75), 88% (15/17) and 72% (46/64), respectively (χ²=21.325, P<0.05). The eradication rate in the culture successful group was significantly higher than that in empirical eradication therapy group (χ²=21.005, P<0.05), while there was no difference between empirical eradication therapy group and culture failed group (χ²=1.154, P=0.283). Conclusion Eradication regimen based on bacterial susceptibility and CYP2C19 genotype should be considered in children with refractory Hp infection.