1.Estimated glomerular filtration rate in alcohol use disorder people
Erdenebat N ; Khorolgarav A ; Narantsatsral D ; Zoljargal S ; Oyunchimeg Ch
Diagnosis 2024;111(4):42-46
Background:
The purpose of this study is to evaluate serum creatinine as a marker of estimated glomerular filtration rate (eGFR) in alcohol use disorder people, and to determine correlation between mean arterial pressure (MAP) and eGFR in chronic kidney disease classification level.
Methods:
In this study, 99 people were examined between January 2024 to November 2024. We measured serum
creatinine based GFR using the Cockroft Gault formula. Results were analyzed SPSS.
Result:
The mean subject age was 48.2±9.9 years, male: female ratio was 5:1. Mean arterial pressure was 103±13.5 mmHg, eGFR 95.5±28.8 ml/min/1.73m2, and mean arterial pressure was significantly correlated with estimated glomerular filtration rate (P<0.05) and no difference between male and female recipients.
Conclusion
According to our research, one of the optimal methods for assessing kidney function is the creatinine-based CKD calculation method, and excessive alcohol consumption is a risk factor for chronic kidney disease, as well as one of the main causes of complication and mortality in cardiovascular disease.
2.Estimated glomerular filtration rate in alcohol use disorder people
Khorolgarav A ; Narantsatsral D ; Oyundelger M ; Zoljargal S ; Oyunchimeg D ; Erdenebat N
Diagnosis 2025;112(1):5-9
Background:
The purpose of this study is to evaluate serum creatinine as a marker of estimated glomerular filtration rate (eGFR) in alcohol use disorder people, and to determine correlation between mean arterial pressure (MAP) and eGFR in chronic kidney disease classification level.
Methods:
In this study, 118 people were examined 2024. We measured serum creatinine based GFR using the Cockroft Gault formula. Biochemical analysis and serum creatinine were evaluated using a fully automatic analyzer (GOLSITE, China). Statistical results were analyzed SPSS.
Result:
The mean subject age was 48.6±10.3, BMI 25.3±3.7 and male: female ratio was 5:1. Mean arterial pressure was 104±12.8 mmHg, eGFR 94±28 ml/ min/1.73m2, and mean arterial pressure was significantly correlated with estimated glomerular filtration rate (P<0.05) and no difference between male and female recipients. Mean eGFR was calculated into 4 groups of 10-year intervals, that eGFR was decreased significantly with age groups. For the alcohol dependence stages of the Michigan Test, the mean eGFR was stage 1 is 112 ml/min/1.73m2, stage 2 is 89 ml/min/1.73m2, stage 3 is 97 ml/min/1.73m2 and there is not statistically significant correlation between Michigan test scores and eGFR.
Conclusion
According to our research, one of the optimal methods for assessing kidney function is the creatinine-based CKD calculation method, and long-term excessive alcohol consumption is a risk factor for CKD, as well as one of the main causes of death due to hypertension and cardiovascular disease.
3.The assessment of the current situation of laboratory diagnostic services among family health centers in Ulaanbaatar
Narantsatsral G ; Baljinnyam B ; Myagmartseren D ; Zesemdorj O
Mongolian Journal of Health Sciences 2025;88(4):154-159
Background:
Mongolia’s long-term development policy, Vision 2050, aims to ensure that every citizen has full access
to primary health care services and to increase the country’s average life expectancy. According to the “Primary Health
Care Service Quality and Accessibility Survey,” the diagnostic capacity of family health centers (FHCs) in Mongolia
was 42.1%. There is a need to further identify issues related to laboratory human resources, equipment supply, quality
assurance, and monitoring.
Aim:
To assess the current status of laboratory diagnostic services in family health centers in Ulaanbaatar city.
Materials and Methods:
The study collected data using a questionnaire developed based on resources such as the
WHO’s Service Availability and Readiness Assessment (SARA), USAID’s Laboratory Assessment Tools, the Ministry
of Health’s 2023 Order No. A/283 on updated guidelines for services provided by family, soum, and bagh health centers,
and the national standard “Structure and Operation of Family Health Centers (MNS 5292:2017).” A total of 46 FHCs in
Ulaanbaatar were randomly selected for the study.
Results:
The average population served by the participating FHCs was 10,228±4043, with 73.9% (n=34) serving over
8,000 people. On average, each center employed 5±2 physicians and nurses. A clinical pathologist was employed at 50.0%
(n=23) of the centers, of which 26.1% (n=6) were full-time and 73.9% (n=17) were contract-based. Availability of laboratory equipment was as follows: Complete blood count (CBC) analyzers: 60.9% (n=28) Biochemistry analyzers: 50.0%
(n=23) Urinalysis equipment: 97.8% (n=45) The availability of laboratory equipment was not significantly associated
with the size of the population served (p=0.54; p=0.63; p=0.74). Among FHCs with laboratory equipment: 82.1% (n=23)
performed CBC tests 87.0% (n=20) performed biochemistry tests 97.8% (n=44) conducted urinalysis tests. Participation
in internal and external quality control programs was significantly higher among centers with specialized laboratory staff
compared to those without (p=0.008; p=0.08). The number of tests and biochemistry parameters performed was also significantly higher in centers with specialized laboratory personnel (p=0.001, p=0.001). However, the availability and use of
rapid diagnostic tests did not differ based on population size or the presence of specialized laboratory staff (p=0.8; p=0.6).
Conclusion
1. In Ulaanbaatar, only half of the family health centers have specialized laboratory personnel.
2. Laboratory equipment availability was between 50.0% and 60.9%. Centers with specialized laboratory staff showed
significantly better performance in internal and external quality control and broader diagnostic testing services.
3. Differences in diagnostic services were associated with both the population size served and the availability of specialized laboratory staff, indicating the need to strengthen primary health care accessibility and capacity.