1.Review of Surgical Cases of Gastric Cancer
Nobuyuki KOBAYASHI ; Fusakuni KURODA ; Takashi DOI ; Makoto KINOUCHI ; Yasuhiro WATANABE ; Akira ODA ; Naoyuki KANEKO
Journal of the Japanese Association of Rural Medicine 2003;51(6):939-943
This paper describes a clinical review of cases of gastric cancer treated surgically at the Department of Surgery of the Shirakawa Kosei General Hospital, the core medical institution in the southern part of Fukushima Prefecture.
During the period of 20 years from January 1981 through December 2000, a total of 1, 132 cases were operated on for gastric carcinoma. Surgical resection cases totaled 1, 023 (resection ratio: 90.4%); curative resection cases, 894 (curative resection ratio: 79.0%); 5-year survival rate for resection cases, 68.3%; and 5-year survival rate for curative resection cases, 75.6%. When the cases were divided into those treated during the first half of the 20 years nad those treated during the latter half of the 20 years, the number or resection cases was smaller during the latter than during the first half but the resection ratio was larger. The early stomach cancer cases in terms of the degree of progress, histological classification, depth and metastasis to lymph nodes have been increasing and the 5-year survival rate has been on the rise.
2.Review of Surgical Cases of Colorectal Cancer
Nobuyiki KOBAYASHI ; Fusakuni KURODA ; Takashi DOI ; Makoto KINOUCHI ; Yasuhiro WATANABE ; Naoyuki KANEKO ; Manabu SATOU
Journal of the Japanese Association of Rural Medicine 2004;53(1):75-79
During the period of 25 years from January 1978 through December 2002, a total of 808 colorectal cancer cases were operated on in Shirakawa Kosei General Hospital. The number of sugical resection cases came to 713 (ratio : 88.25%). Curative resection was performed on 593 cases (ratio : 73.4%). The total number of cases was broken down into 446 cases of cancer of the colon and 369 cases of cancer of the rectum (7 multiple cancer cases included). By sex, male cases numbered 329 and female cases 379. Clinically or histologically, many cases were diagnosed as stage IIIa or stage II cancer. The 5-year-survival rate for the resection cases was calculated at 67.2% and that for the cure resection cases, at 79.5%.
Excision
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Malignant Neoplasms
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3.Effects of tu-chung extract administrating on serum testosterone in hindlimb-suspended rats .
GANG-JIAN QU ; HIROSHI KANEKO ; NAOYUKI EBINE ; KAYOKO KITA ; SEIJI TOMITA ; TOSHIO MIKAMI ; YOUSUKE TASAKI ; AKIRA ITO
Japanese Journal of Physical Fitness and Sports Medicine 1999;48(4):501-507
The purpose of this research was to study the effects of Tu-Chung extract (Eucommia ulmoides OLIV.) administration on serum testosterone and the possible mechanisms in hindlimb- suspended rats. 25 five-week old male Wistar rats were used. All rats were randomly divided into two groups : those treated with Tu-Chung extract (Tu-Chung G, n=suspended for 37 days in hindlimb. 1 mg/ml Tu-Chung extract was administered orally once daily at a dose of 1 ml/100 g body weight. Distilled water was administered in a similar way to the control group. The following results were observed :
1. Serum testosterone concentration in Tu-Chung G was significantly higher than in Cont. G (P<0.001) .
2. There was no significant difference between Tu-Chung G and Cont. G in serum LB concentrations.
3. The Testicular cAMP level in Tu-Chung G was significantly higher than that in Cont. G (P<0.01) .
4. 24-h urinary excretion of 17-ketosteroid in Tu-Chung G was significantly higher than that in Cont. G (P<0.001) .
5. There were no significant differences between the two groups in the weights per body weight of the kidneys, adrenal grand and testes. These results suggest that the adininstration of Tu-Chung extract inducing high serum testosterone concentrations in hindlimb-suspended rats might be due to enhanced testicular and adrenal functions, not pituitary.
4.10-3 Effects of essential oil from the leaves of Abies sachalinensis on salivary stress markers and mood profile
Yoshinori OHTSUKA ; Takaaki KITAGAWA ; Toshihiko KANEKO ; Naoyuki MATSUI ; Tatsuro OHIRA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 2014;77(5):500-500
Objectives: To investigate the stress-relief and mood-change effects of extractives from the leaves of Abies sachalinensis Methods: The essential oil was steam-distilled from the leaves of Abies sachalinensis (Todomatsu) and it was a generous gift from Japan Aroma Laboratory. Ten healthy university students (male 8, female 2) participated in the present study. After informed consent was obtained, the subject sat on a chair in a climatic chamber in which temperature and relative humidity were kept at 24°C and 50%, respectively. After ten min rest in a room, first salivary collection for cortisol, amylase and questionnaire with mood check list short form 2 (MCL-S.2) were performed. Second measurement was done after 20 min rest without aroma and then further 20 min later with aroma, third measurement was done. None felt discomfort during the experiment. Differences between the three measurements were examined using Friedman test, then if there is any significant differences, Scheffe’ test was performed. Results and Conclusion: Regarding the emotional changes, higher “relaxation” score and lower “anxiety” score were observed in the cases with aroma (third measurement) than those without aroma (second measurement, p<0.05). “Pleasantness” score did not show significant changes. No significant differences between first and second measurements. Salivary stress parameter such as cortisol decreased significantly in the subjects with aroma (first vs. third, p=0.001). There was also significant difference between second and third measurements (p<0.05). Salivary amylase activity showed lower value with aroma than the resting value (first vs. third, p<0.05). From these findings, essential oil from the leaves of Abies sachalinensis (Todomatsu) assumed to improve mood status and have a stress-relief activity.