Systemic infection by MRSA (Methicillin-resistant Staphylococcus aureus) is a risk in immunodeficient patients such as those with severe burn injuries. Hozai, formulations with tonic effects, may enhance the immune system and we treated two severe burn patients with MRSA infections using Juzentaihoto, which is a remedy for kikyo (deficiency of vital energy) and kekkyo (ketsu deficiency). Both patients suffered flame burns [85% body surface area (BSA) and 40% BSA] and inhalation injuries committing self-immolation. They contracted MRSA in due course and antibiotics such as Arbekacin or Teicoplanin did not control MRSA. Therefore, Juzentaihoto was administered through a nasogastric tube and both of them were finally cured without complications. Juzentaihoto may be useful against fatigue, anemia, malaise, ulcer, and purulent wounds due to severe burns.
Methicillin-resistant staphylococcus aureus infection ; Physical trauma ; Cases ; Infections of musculoskeletal system ; Burn brand of nitrofurazone

Heart rate (HR) corresponding to lactate threshold (LT) was evaluated in patients with multiple risk factors and applied to determine the target HR by Karvonen's formula calculated from the predicted HR max. The subjects were 52 outpatients (33 men and 19 women) aged from 23 to 70 years old (mean 46.9) with more than 2 risk factors including obesity, hypertension, diabetes mellitus, impaired glucose tolerance, dyslipidemia, hyperuricemia, and hyperinsulinemia. A multistage graded test of submaximal exercise on electric bicycle ergometer was performed for each subject before starting exercise therapy. The workload was increased every 4 minutes, and heart rate, blood pressure, and blood lactate concentration were measured during the last 1 minute of each stage. The LTHR ranged from 80 to 120 beats/min (mean 101±10) and Karvonen's coefficients ranged from 0.08 to 0.40 (mean 0.22±0.08) . Because of these differences and variance, it is suggested that LTHR should be measured directly or about 20% HR reserve should be prescribed at least when starting exercise therapy for these cases.