1.Comparison of Dissolution Rates of Levofloxacin Tablets Produced by 4 Manufactures
China Pharmacy 2005;0(22):-
OBJECTIVE:To compare the dissolution rates of levofloxacin tablets produced in 4 domestic pharmaceutical manufacturers in order to provide the evidence for its clinical use.METHODS:UV spectrohpotmetry was used to determine the cumulative dissolution rates of these 4 kinds of levofloxacin tablets at different time points,the dissolution parameters of T50,Td,T80,and M were calculated by Weibull formula,then variance analysis was made.RESULTS:The dissolution rates of these 4 kinds of levofloxacin tablets all met the standards recorded in 2000 edition of China Pharmacopoeia,but significant differences were found in parameters of T50,Td,T80,and M(P
2.Determination of 7 Kinds of Amino Acid in Compound Amino Acid Capsules with Online Derivation-Diode Array Detector
Nansong WANG ; Guangming HE ; Lijun WANG
China Pharmacy 1991;0(06):-
OBJECTIVE:To develop a HPLC assay for the determination of 7 kinds of amino acids in amino acid capsules by using online derivation and diode array detector.METHODS:The high performance chromatograph of liquid with the device of automatic derivation was employed as the automatic sampler.The samples were injected in the predefined procedure,and detected with the diode array detector.RESULTS:Good resolution of 7 kinds of amino acids was obtained,and the respective detectable concentration showed a good linear relationship with its peak area.CONCLUSION:The present method is convenient,well reproduced, highly sensitive,and accurate,therefore it can be widely used.
3.Studies on the Quality Standard of Compound Polysaccharide Selenate Capsules
Guangming HE ; Jun MENG ; Nansong WANG
China Pharmacy 1991;0(04):-
OBJECTIVE:To study the quality standard of compound polysaccharide selenate capsules(CPSC).METHODS:Astragalus and oldenlandia were identified by TLC method and the content of selenium in CPSC was determined by fluo?rospectrophotometry.RESULTS:Linear range was0~0.5?g/ml and average recovery was100.4%,RSD=0.91%(n=5). CONCLUSION:This method is simple and accurate,and can be used for quality control of CPSC.