1.The study of certain risk factors of gout and asymptomatic hyperuricemia
Demchigmaa N ; Zulgerel N ; Namuuntuul D ; Tsolmon D ; Altanzul B ; Oyuntugs B ; Devshil Z
Mongolian Journal of Health Sciences 2025;86(2):131-137
Background:
Gout is a chronic inflammatory joint disease that damages many joints. Monosodium urate-deposition
accumulates in the joints and soft tissues due to long-term untreated condition and leading to loss of function, further
reducing the quality of life. It is the most common inflammatory joint disease in the world. Hyperuricemia, sedentary
lifestyle including diet, obesity, and the use of certain medications are risk factors for gout. A study published in the Asia
Pacific Journal of Nutrition in 2018 found that excessive consumption of meat, alcohol, carbonated beverages, and fructose
containing drinks increases serum uric acid levels and the risk of gout.
Aim:
To investigate certain risk factors associated with gout and asymptomatic hyperuricemia among study participants.
Materials and Methods:
This study was conducted using an analytical cross-sectional design. Data were coded, error-
checked, and analyzed using the SPSS 29.0 software.
Results:
A total of 145 individuals participated in the study, with an average age of 55.0 ± 13.9 years, and 75.2% were
male. Based on diagnostic criteria, 29.7% had gout, 35.2% had asymptomatic hyperuricemia, and 35.2% had normal uric
acid levels. The consumption of different food products over the past month was analyzed among study groups, and alcohol
intake was found to be statistically significant. A univariate regression analysis showed that obesity was associated
with hyperuricemia, male sex was associated with gout, and alcohol consumption was a potential risk factor for both
hyperuricemia and gout.
Conclusion
Among the study participants, 29.7% had gout, and 35.2% had asymptomatic hyperuricemia. Obesity, male
sex, and alcohol consumption were identified as risk factors contributing to increased serum uric acid levels and gout
development.