1.Preliminary evaluation on the effects of VG99 on some clinical and laboratory parameters in patients with chronic hepatitis B
Journal Reasearch of Vietnam Traditional Medicine and Pharmacy 2003;0(11):36-40
The fluid extract VGG was processed from Phyllanthus amarus, Adenosma caeruleum, Plantago asiatica, Centella asiatica, Schisandra chinensis, Curcuma aromatica and Rheum officinale. The acute toxicity experiment proved that VGG was nontoxic. The clinical trial included 18 chronic hepatitis B sufferers receiving VGG 50ml/day for 2 months. The study results showed a significant improvement in almost clinical symptoms, and a decline in transaminase level. There was no change in bilirubin, total protein. From the point of view of diseases classification in traditional medicine, VGG effect was better for patients with liver-heat and spleen-damp syndromes than those with stag nation of the liver-qi and deficiency of the spleen. No adverse drug reactions were observed
Hepatitis B, Chronic
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Patients
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Medicine, Traditional
2.Mesocyclops species and their potential in killing Aedes aegypti larvae in Vietnam
Journal of Practical Medicine 2002;435(11):11-14
Mesocyclops were collected from 631 water areas and fresh water containers over 31 provinces and city between 1998 - 1999. It was found 10 species that involved in Mesocyclops gender. Messocyclops distribute widely and are available in fresh water containers in crowded regions. They can reproduce and develop easily under natural conditions. They have high potential in killing Aedes aegypti larvae. Mesocyclops can become an effective biological agent in preventing actively the Dengue fever/Dengue hemorrhage vector in Viet Nam
Copepoda
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Densovirinae
3.Application of Mesocyclops in community for control dengue fever/hemorrhage vector in some locals of ViÖt Nam
Journal of Practical Medicine 2002;435(11):48-52
Source of Aedes larvae was investigated in 200 households in provinces of Hµ T©y, Thõa thiªn HuÕ, §µ N½ng, Kh¸nh Hßa, Kiªn giang between 1998 - 2000. Mesocyclops were released to water containers and the waste water containers were eliminated. the results showed that in Northern area, mosquito and larvae population reduced by 100% after 13 months of project and maintained for several following months. In Central area, larvae population reduced by 90,7% and mosquito by 39.2% to 71.8%. In southern area, larvae population reduced by 97.7%, mosquito by 92.0% and there was not patient with dengue fever
Copepoda
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Dengue
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Dengue Hemorrhagic Fever
4.Field training active control the hemorrhagic fever vector in T©n Minh commune, Thêng TÝn district, Hµ T©y province during 1995-1999
Journal of Practical Medicine 2002;435(11):20-23
Subject 6928 persons in 1454 households, T©n Minh commune, Thêng TÝn district, Hµ T©y province where the dengue hemorrhagic fever occurred during 1988 -1992. Methods: survey of focus of Aedes aegypti, training, and education for public perception, release of Mesocyclops in the field training and monitoring the vector. Results: the education for enhancement of the public perception, release of mesocyclops and removal of the wasted objects gave the long-term social and economic efficacy. These were easy to implement and can be enlarged to other areas to actively control the epidemic fever/ dengue hemorrhagic fever
Dengue Hemorrhagic Fever
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Copepoda
5.Prospect of using mesocyclops for dengue vector control in Viet Nam.
Journal of Preventive Medicine 2002;12(2):47-53
8 species of Mesocyclops were reported in Viet Nam having wide distribution and existing naturally in certain drinking water containers of inhabitants. Mesocyclops can survive and develop well in normal condition and they are good preditors to the first instar of Aedes aegypti larvae, the major vector of dengue fever/dengue haemorrhagic fever. In the laboratory, a single Mesocyclops can kill first-instar of Aedes acgypti larvae up to 41 by M.rutneri, 37 by M.aspericorms and 31 by M.woutersi in average during 24 hours. In the fields releasing Mesocyclops (to all kind of water containers), population of Aedes aegypti reduced from 91.5% to 100% after 17 months treating and sustaining for months later
Copepoda
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dengue
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Viet Nam
6.Therapeutic effects of the traditional medicine BTB combined in treatment of Helicobacter Pylori (HP) infected chronic gastritis
Journal of Medical Research 2008;55(3):58-62
Background: In traditional medicine, there are some herbal medicines and remedies for the treatment of Helicobacter Pylori (HP) infected chronic gastritis. BTB is a remedy that Betelvine combined with \u201cTa kim hoan\u201d remedy and \u201cBach thuoc Cam thao thang\u201d. These medicines are manufactured by the National Hospital of Traditional Medicine. Objectives: (1) To research the analgesic effects, change of endoscopic and histopathological images, anti-HP effects of BTB in the treatment of the HP-infected chronic gastritis. (2) To investigate unexpected side effects of BTB in clinical practice. Subjects and method: 37 chronic gastritis patients with positive HP (based on clinical, endoscopic and histopathological evidences). This was an opened clinical study, comparing results between pre- and post-treatment. Results: BTB could stop epigastric pain (89.2%). The rate of recovering in endoscopic signs was 75.7%. The histopathological results showed that BTB reduced significantly the inflammation level (73% good results); anti-HP rate was 59.5%. Conclusions: In treatment of HP-infected chronic gastritis, BTB could stop pain up to 89.2%. The inflammation level reduced significantly on endoscopic and histopathological images. BTB did not have any unexpected clinical effects.
Traditional medicine
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gastritis
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Helicobacter pylori
7.Therapeutic effects of HTA capsules in the supportive treatment of HIV/AIDS patients
Journal of Medical Research 2008;55(3):63-67
Background: HIV/AIDS cases are increasing in Viet Nam. It is very difficult to treat for these cases because the cost of pharmaceutical medicines is high. HTA capsule\u2019s components include Radix Astragali, Flos Lonicerae, Herba Andrographis, Radix Achyranthis, Rhizoma Lateralis Curcumae, Flos Chrysanthemi, Semen Vignae Cylindricae, Radix Pallopiae. Objectives: (1) To evaluate on clinical effects of the HTA capsules in the supportive treatment of HIV/AIDS patients. (2) To evaluate any intensive special effects via TCD4; (3) To investigate unexpectable side effects of HTA capsules. Subjects and method: 38 HIV patients treated in the Department of Clinical Medicine of Tropical Diseases of Dong Da hospital in Ha Noi. This was a prospective, opened, clinical controlled trial. Results: HTA capsules raised patient\u2019s weight on average by 2.38 kg (p<0.001); Karnofsky index increased on average 4.8 points (p<0.05). In the HTA-treated group, 5 patients (23.81%) recovered well, none inferior in comparison with the control group: nobody feft better and worse cases still increased (23.43%). HTA increased TCD4 cells an average 43.9 cells/mm3 blood (p<0.05). Conclusions: HTA capsules improved clinical status such as raised average weight, raised Karnofsky index based on clinical classification (CDC \u2013 1993). 23.81% of patients recovered well and no one was worsened by the HTA capsules. HTA increased TCD4 cells. HTA capsules did not have any unexpected clinical effects.
Traditional medicine
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HIV/AIDS
8.Histopathology of gastric mucous membrane in patients with duodenal ulcer before and after treatment with Che day (Ampelopsis Cantoniensis Planch)
Journal of Medical Research 2008;56(4):62-66
Introduction: Che day (Ampelopsis Cantoniensis Planch) is a medicinal herb that has been used for a long time in Vietnamese Traditional Medicine for treating gastroduodenal ulcer. Scientific studies found that Che day has some chemical components such as flavonoids, tannins and uronic compounds that can neutralize the gastric acidity. Objectives: This study was conducted with the aim of evaluating the H pylori eradication ability and the anti-inflammation properties of Che day for duodenal ulcer, using histopathological measures. Subjects and method: 43 patients with endoscopy-confirmed diagnosis of duodenal ulcer were involved in the opening clinical trial. Ages of patients were ranged from 18 to 65 years old. The patients were treated for 6 weeks by dried extracts of Che day (four 5gr-sachets divided into 4 times a day) and underwent endoscopic biopsy before and post-treatment. Results: Che day had the HP eradication effect in 17/43 patients (42.5%), as seen in histophathological examinations. This results were significant with p <0.001. The rate of recovering patients reached up to 23.26% (10/43 patients) and the rate of severe cases reduced dramatically (18/20 patients). The comparison before and after 6 weeks of treatment showed the prevention effect of Che day from gastritis with statistic significance (p<0.001). Conclusion: Che day has the HP eradication ability with the rate reaching up to 42.5%. This herb reduced the gastritis in histopathological studies. 23.26% of patients recovered from duodenal ulcer after treatment and the severe cases were dramatically reduced.
Ampelopsis Cantoniensis Planch
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Duodenal ulcer
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Gastritis
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Helicobacter pylori
9.Evaluation on the therapeutic effects of Che day in the treatment for gastro-duodenal ulcer in clinical, endoscopy and pathological anatomy
Nam -- Vu ; Trach Khanh Nguyen
Journal of Medical Research 2008;59(6):54-59
Background: Che day is a commonly used traditional medicine among the mountainous ethnic people to treat gastro-duodenal ulcer. Its scientific name is Ampelopsis Cantoniensis Planch (Vitaceae). It is known that chemical components of che day includes flavonoid, tanin and uronic compound, which is able to relieve pain completely. Objectives: Evaluation of analgesic, cicatrisation, anti-inflammation and Helicobacter Pylori (HP) eradicating effects of che day in the treatment of gastro-duodenal ulcer and also investigate the side effects of che day. Subject and methods: 80 patients with gastro-duodenal ulcers were seen with endoscopy, suffering from epigastric pain. The study was carried out in the way of a double - blind method, comparing the results between the group che day and the Alusi cotrolled group. Results: On average, the time when the pain receded is 8.9 days in the che day group, faster than the Alusi controlled group (17.35 days, p < 0.01). The rate of the cicatrisation by che day is 79.55%, higher than the Alusi (47.22%; p < 0.001). In pathological anatomy, the rate of HP eradicating of che day is 42.5%, higher than the Alusi (19.35%, p < 0.01); the rate of recovery from gastritis of che day is 23.25%, higher than the Alusi (9.09%, p < 0.01) and the rate of total recovery of che day is 44.19%, higher than the Alusi; (27.27%, p < 0.01), Conclusions: The che day is effective in relieving gastro-duodenal ulcer \u2013 induced pain for the average of 9 days. In endoscopy, the rate of cicatrisation of che day is 79.55%, in which, good cicatrisation is 54.28%. In pathological anatomy, the che day is effective in eridicating HP with the rate of 42.5 %; The rate of recovery is 23.25% and che day has no side effects.
traditional medication
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gastro-duodenal ulcer
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gastritis
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helicobacter pylori
10.Evaluation of the efficacy of cynoff 25 ULV to eradicate aedes species, dengue vectors in Vietnam, 2004
Nam Sinh Vu ; Yen Thi Nguyen ; Tu Cong Tran ; Duc Minh Hoang ; Dung Chi Tham
Journal of Preventive Medicine 2008;18(2):23-31
Background: Dengue fever remains a major public health problem in Vietnam. It was transmitted through two main Aedes species, namely Aedes aegypti and Aedes albopictus in which Aedes aegypti played the predominant role in transmitting the dengue viruses (accounted for 94% of the Aedes genus).Different groups of insecticides have been widely used in the community. As a consequence, it increased the resistance level of Aedes vectors to the insecticides. Therefore, a new synthesized insecticide was required for future control and prevention of dengue epidemics. \r\n', u'Objectives: To evaluate the efficacy of Cynoff 25 ULV in suppressing Aedes species in Vietnam. \r\n', u'Subjects and methods: The study was conducted in the entomology laboratory and in the fields of Ha Tay province. ULV spraying was implemented in Hiengiang commune, Thuongtin district, in comparison with a control area, Van Mo commune in Ha Dong town.\r\n', u'Results and conclusions: : Cynoff 25 ULV had a high efficacy that kills over 90% of 2 dengue vector species, namely Aedes aegypti and Aedes albopicctus after 24 hours exposure at the distance of 30 meters from the brass nozzle of a STIHL SR 400 sprayer. In the field trials, Cynoff 25 ULV also had high efficacy in killing Aedes species, e.g. 100% of Aedes species were killed after spraying and the effects lasted for 3 months for Aedes aegypti and one month for Aedes albopictus species. The insecticide had no side-effects or any other adverse effects to humans, livestock and the environment in the intervention areas. \r\n', u'
cynoff 25 ULV
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aedes species
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dengue vectors