Introduction: Quality control in medical laboratory includes internal quality control and external quality control is very necessary for the quality management of medical laboratory tests. However, many laboratories for different reasons have not carried out quality control, its benefits, as well as inadequately evaluated affected risks of laboratory test quality. \r\n', u'Objectives: Two objectives are set for the research. First, to evaluate the quality of blood biochemical tests in some of the provinces, districts and private laboratories in the North of Vietnam. Second, factors that affect the quality of the medical laboratory tests are also examined. \r\n', u'Subjects and method: In this study, human control serum of Biorad is sent as ordinary blood samples to the 6 provincial, 12 district and 10 private laboratories to analyze some normal blood biomedical indexes. We also collected the necessary information on staff, equipments, and chemicals\u2026of the laboratories.\r\n', u'Results: There are five main findings in the areas of (1) general information about the laboratories, (2) laboratory test results of blood biochemical indexes with true value at the normal level, (3) laboratory test results of blood biochemical indexes with true value at the pathological level (level 2), (4) the accuracy of laboratory test results based on the blood test sample level 1, (5) the accuracy of laboratory test results based on the blood test sample level 2. In general, the first results of analyzed biomedical indexes are very different by statistical calculation between laboratories. \r\n', u'Conclusion: The research results indicated that the quality of analyzed biomedical indexes in some laboratories is not ensured. It is necessary to find the reasons and the ways to resolve the problem. \r\n', u'
Quality control ; Clinical test

Objective To screen Vietnamese medicinal plants for xanthine oxidase (XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant. Methods The plants materials were extracted by methanol. The active plant materials were fractionated using different organic solvents, including n-hexane, ethyl acetate, and n-butanol. Bioassay-guided fractionation and column chromatography were used to isolate compounds. The compounds structures were elucidated by analysis of spectroscopic data, including IR, MS, and NMR. Results Three hundreds and eleven methanol extracts (CME) belonging to 301 Vietnamese herbs were screened for XO inhibitory activity. Among these plants, 57 extracts displayed XO inhibitory activity at 100 μg/mL with inhibition rates of over 50%. The extracts of Archidendron clypearia (A. clypearia), Smilax poilanei, Linociera ramiflora and Passiflora foetida exhibited the greatest potency with IC