Objective To investigate the effect of pre- and post-menopausal periods and menopausal-age limit on lipid metabolism in hypertensive women. Methods One hundred thirty-one hypertensive women in pre- or post-menopausal periods were collected for the determination of blood triglycerides(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C)and low density lipoprotein(LDL-C). The blood lipid levels were compared between hypertensive and control groups,as well as between pre- and post-menopausal subgroups,and the relationship between menopausal-age limit and blood levels lipid was analyzed. Results Hypertensive group in pre-menopausal period had significantly higher TC and LDL-C than did the control group〔TC,(5.27?0.47)vs(4.33?0.70)mmol/L;LDL-C,(3.50?0.45)vs(2.67?0.50)mmol/L respectively, all P

Objective To investigate the role and clinical significance of estrogen in the proliferation of colorectal carcinomas (CC). Methods The estrogen receptor (ER) expression and the Cyclin D 1 expression were quantitatively determined by flow cytometry in 30 cases of CC and 10 cases of normal colorectal tissues (NCT). Meanwhile, the expressions of ER and proliferating cell nuclear antigen (PCNA) protein were exa mined immunohistochemically in the same cases. Results FCM analysis showed that the ER expression in CC (1.36?0.32) was significantly stronger than that in NCT(1.00?0.05, P