Objective:To investigate the mechanism of Chuan Shen Tong Injection (CSTI) for benign prostatic hyperplasia (BPH).Methods:The distribution of epidermal growth factor (EGF) and epidermal growth factor receptor(EGFR) expression were detected with immunohistochemical technique in 49 samples of the excised prostate. Among them, 18 samples were from patients without intraglandular injection of CSTI (group A) as controls, 21 from those receiving injection but without effect (group B) and 10 from those receiving injection with effect but recur (group C).Results: The positive expression rates of interstitial EGF and EGFR in group B (81% and 71.4% respectively) increased as compared with group A (33.3% and 33.3% respectively.,P

Objective: To investigate the mechanism of Chuanshentong injection (CJ) in treating benign prostatic hyperplasia (BPH). Methods: The expression of androgen receptor (AR), estrogen receptor (ER), progesterone receptor (PR) was examined with immunohistochemical technique in 49 cases of BPH. Among 49 cases, 18 served as control (group A), 21 failed in the treatment of CJ (group B) and 10 recurrent (group C) after CJ treatment. Results: As compared with Group A, the positive rate of ER expression (81 %vs 38.9 %, P