The effects of noradrenaline,isoptin.prostaglandin E and indomethacin on the dynamics and the muscloelectrical activities of the ureter were sutdied in dogs.It was found that no-radrenaline exerted excitation on the smooth muscle of the upper ureter,isoptin could remarkably reduce both the electrical and contractile activities of the ureter,prostaglandin E could intensify the activeites of the ureter,and indomethacin could the inhibit the synthesis of intrinsic prostaglandins and in turn relax the smooth muscle of the ureter.

The effects of autonomic drugs on the activities of the upper urinary tract were studies with the ureteral perfusion pressure method.It was found that a-adrenergic and M-cholinergic receptors possess excitatory effect on the upper urinary tract while ?-adrenergic receptor possess inhibitory effect.It is likely that a-adrenergic receptor plays a certaion role in the maintenance of the normal activity of the upper urinary tract but both the M-and ?-receptors have a little effects.The effects of the autonomic nervous system and its receptors on the activities of the upper urinary tract were discussed.