Objective To evaluate the distribution characteristics of left ventricular systolic dyssynchrony (LV-SD) in dilated cardiomyopathy (DCM) patients with chronic heart failure (CHF) and normal QRS wave width, by pulsed-wave Doppler tissue imaging (PW-DTI), and study its relation with left ventricular systolic function, ventricular remodeling, and functional mitral regurgitation (FMR). Methods The time to peak systolic velocity (Ts) in 12 left ventricular segments was evaluated by PW-DTI, from which the standard deviation (SD) of Ts in the 12 segments (Ts-SD) and maximum Ts difference (Ts-maxD) were calculated. Results Ts-SD and Ts-maxD in the 12 LV segments of the DCM patients with CHF were significantly higher than those of the healthy controls (P＜0.01). In DCM patients with CHF and normal QRS wave width, the incidence of LV-SD was 29.8% (14/47) and the inferior wall was the most frequent distribution site of contraction delay. Linear regression analysis revealed a negative correlation between Ts-SD, Ts-maxD, and left ventricular ejection fraction (LVEF) (P＜0.01), but a positive correlation between Ts-SD, Ts-maxD and left ventricular end-diastolic volume (LVEDV), lefe ventricular end-systolic volume (LVESV), New York Heart Association (NYHA) cardiac function, FMR (P＜0.01) in DCM patients with CHF. Conclusion LV-SD exists in DCM patients with normal QRS width. LV-SD aggravates the LV systolic function damage, which is closely associated with left ventricular remodeling. LV-SD may contribute to the FMR in DCM patients.

Objective To explore the changes of GRO-α and VEGF in the peritoneal fluid of women with endometriosis and their correlation. Methods The levels of GRO-α and VEGF were detected by enzyme linked immunosorbent assay ( ELISA ) method in 39 cases of endometriosis and 25 normal cases of without endometriosis. Results The levels of GRO-αand VEGF in the peritoneal fluid of EMs group were ( 108.77 ± 20. 58 ) pg/ml and ( 199. 67 ± 99. 26 ) pg/ml separately, and it was significantly higher than those in control group ( 71.07 ± 18. 96 ) pg/ml, ( 115.46 ± 32. 39 ) pg/ml. The differences were statically significant( P <0. 05). The level of GRO-α in the peritoneal fluid of the patients in stage Ⅰ and Ⅱ was sig-nificantly lower than that in stage Ⅲ and Ⅳ[(99.43 ± 16.05)pg/ml vs (117.65 ± 20.8)pg/ml, P <0. 05] , while the level of VEGF in the peritoneal fluid of the patients in stage Ⅰ and Ⅱ was significantly higher than that in stage Ⅲ and Ⅳ[(246. 89 ± 114. 34) pg/ml vs ( 152. 82 ± 54. 55 ) pg/ml, P < 0. 05] .There was positive correlation between the level of GRO-α and r-AFS ( r = 0. 439, P < 0. 05 ), but no cor-relation between the level of VEGF and r-AFS ( r = -0. 210, P >0.05). There was no correlation be-tween peritoneal fluid levels of GRO-α and VEGF in the EMs group ( r =-0. 05, P>0. 05). Conclusion Compared with control group, the levels of GRO-α and VEGF in peritoneal fluid of women with endome-triosis were significantly increased, which indicated that the increased GR0-α and VEGF secretion involved in the pathogenesis of this disease. There was correlation between the peritoneal fluid level of GRO-α and the degree of EMs.

Adult ; Churg-Strauss Syndrome ; complications ; Humans ; Male ; Myocardial Infarction ; complications

ObjectiveTo observe the clinical efficacy of acupuncture-moxibustion in treating tinnitus.MethodNinety-eight patients with tinnitus were divided into a warm-needling group (n=32), an acupuncture group (n=34), and a medication group (n=32), to observe thetherapeuticefficacies.ResultThe total effective rate was 83.3% in the warm-needling group, versus 78.8% in the acupuncture group and 60.0% in the medication group.ConclusionWarm needling and acupuncture plus TDP are both superior to the medication treatment in comparing the therapeutic efficacy.

Objective To investigate the mechanism of automatic processing of cartoon facial expressions by using event-related potential(ERP).Methods Sixteen healthy volunteers (7 males and 9 females) were recruited for this study.The subjects were instructed to mentally count green faces (targets) and ignore the red ones (non-targets) including standard neutral expressions and deviant emotional expressions.Thirty two channels electroencephalogram (EEG) was recorded by Neuroscan Nuamps System.The amplitudes of mismatch negativity (MMN) were analyzed.Results (1) MMN1:the amplitudes were(-0.570 ± 0.076) μV (TP7/TP8),(-0.840 ±0.119) μV(A1/A2) ,(-1.199 ±0.105)μV(T5/T6) ,(-1.184 ±0.102)μV(O1/O2).There was a significant main effect of site (F(3,45) = 8.340, P ＜ 0.05 ) and an interaction of orientation × hemisphere (F(1,15) =11.977, P＜0.05).( 2 ) MMN2: the amplitudes were (-0.469 ± 0.126 ) μV ( TP7/TP8 ), (-1.014 ± 0.255 ) μV(A1/A2) ,(-1.071 ±0.182)μV(T5/T6), (-0.915 ±0.178)μV (O1/O2).There was a significant main effect of orientation (F(1,15) = 7.232, P ＜ 0.05 ) and interactions of orientation × type (F(1,15) = 6.458, P ＜ 0.05 )and orientation × hemisphere(F(1,15) = 11.907, P＜0.05 ).Conclusion Cartoon emotional faces elicit expressionrelated MMN indexing automatic processing.The MMN amplitude is right-lateralized and larger for negative than positive expression.

Objective To explore the effect of early drinking on keeping safety and improving comfort of mouth cavity in postoperative patients with transsphenoidal resection of pituitary adenoma. Methods A total of 70 postoperative patients with transsphenoidal resection of pituitary adenoma were divided into the experimental group and the control group with 35 cases each by random number table method. The control group were allowed to drink water after postoperative 6 hours, the experimental group were allowed to drink a small amount of water after 1 h when they recovered from anesthesia. The symptoms of heart rate, respiration, blood pressure, pulse oxygen saturation, nausea, vomiting, mis- aspiration, dry mouth,thirst, sore throat, oral pH value, oral cavity peculiar smell and the mood were observed 6 h after operation. Results After 6 hours, the heart rate, respiration, systolic blood pressure, and pulse oxygen saturation in the two groups were within normal range, which were (79.14±7.82) times per minute vs. (82.29±13.48) times per minute, (17.71± 1.10) times per minute vs. (18.31±1.92) times per minute, (121.66±10.61) mmHg vs.(121.55±12.86) mmHg (1 mmHg=0.133 kPa), (17.71±1.10) times per minute, (0.99±0.01) % vs. (0.99±0.01) %,there was no significant differences( t=-1.603-0.673, P > 0.05). The value of diastolic blood pressure in the control group were lower than that of the experimental group,(70.14±6.87) mmHg vs.( 74.34±7.29) mmHg, there was significant difference ( t=2.497, P < 0.05) .The incidence of mis- aspiration was zero in two groups. The rate of nausea, vomiting were 11.43%(4/35) and 5.71% (2/35) in the experimental group, which were significantly lower than 17.14%(6/35) and 11.43%(4/35) in the control group, there was no significant differences (χ2=0.467,0.182, P > 0.05). The rate of dry mouth,thirst in the experimental group were lower than those of the control group, 2.71±1.74 vs. 7.03± 1.98, 1.77±1.68 vs. 5.06±2.35, the difference was statistically significant (t=-9.685, -6.725, P < 0.01). T he value of sore throat in the experimental group was lower than that in the control group, 3.40±1.72 vs. 4.11± 2.23, there was no significant differences (t=-1.500, P > 0.05). There was difference in oral pH value(6.82±0.17 vs. 6.43±0.25, t=0.815, P < 0.01) between the experimental group and the control group. The rates of oral cavity peculiar smell and the mood in the experimental group were 8.57% (3/35) and 28.57% (10/35), which were better than those of the control group, 82.85% (29/35), 45.71%(16/35), the difference were significant (χ2=4.629, 10.516, P < 0.05). Conclusions Early drinking in postoperative patients with transsphenoidal resection of pituitary adenoma is secure and it can relieve uncomfortable symptoms, maintain normal oral pH value, improve comfort of mouth cavity and keep good mood of patients.

Academic Dissertations as Topic ; Bibliometrics ; China ; Health Systems Agencies ; Occupational Diseases ; prevention & control ; Publishing

Aged ; Aged, 80 and over ; Combined Modality Therapy ; Female ; Humans ; Male ; Middle Aged ; Otorhinolaryngologic Diseases ; therapy ; Retrospective Studies

Humans ; Polyomavirus ; classification ; Polyomavirus Infections ; virology

ObjectiveTo examine the mental health status and its changes among children exposed to the Wenchuan earthquake 2 and 3 years after it has passed,and evaluate the possible influencing factors of mental health.MethodsThe General questionnaire,the self-reported Children's revised impact of event scale(CRIES)and the Depression self-rating scale for children ( DSRSC ) were administered to the same children from the earthquake affected areas 2,3 years after the earthquake.ResultsBoth of the CRIES scores and DSRSC scores had decreased over the 2,3 years periods after the earthquake ( z =- 8.772,P =0.00; z=- 2.870,P =0.00 ).The risk factors associated with PTSD 3 years after the earthquake were:gender (OR =1.069,P =0.00 ),the severity of their family's injury( OR =1.141,P =0.02 ),the length of living in transferred safe places( OR =1.416,P =0.03 ),and whether or not witnessed collapse ( OR =1.014,P =0.01 ).The risk factors associated with depression 3 years after the earthquake were:gender( OR =1.367,P =0.00),age( OR =1.035,P =0.04),and despair( OR =2.490,P =0.01 ).ConclusionBoth of the symptoms of PTSD and depression among the children from earthquake affected areas have decreased over the 2,3 years periods after the earthquake.The mental health status of the children from the earthquake affected areas are influenced by their gender,age,the length of living in transferred safe places,the severity of their family's injury,whether or not witnessed collapse and despair.These factors should be taken into considerations when the long-term post-traumatic psychological interventions are planned.