Clinical Medicine ; Humans ; Infant ; Prospective Studies ; Triazines ; adverse effects ; Urolithiasis ; chemically induced

Objective:To control the maintenance cost of medical equipment and improve the efficiency and service level for maintenance, and to research the management about classification maintenance for medical equipment based on analytic hierarchy process (AHP).Methods: 69 clinical department and 14 engineers were involved in the questionnaire survey and the evaluated factors were obtained from their questionnaires. The (AHP) was used to determine what is the factor weight of maintenance for the medical equipment, and then calculate the maintenance scores of the equipment. Finally, the weight scores were applied to ABC classification method and the equipments will be divided into three types (A\B\C) as this method, and they will be managed by different mode.Results: Depended on the sixth order analysis data from 6 factors of evaluation (price, frequency, stability, running time, standby factor and difficulty of maintenance) that were compared between any two factors by using AHP, through comprehensive scores ratio to got A\B\C classification and work out relative implement countermeasure of maintenance. The new classification management mode has achieved planning and preventive maintenance for key equipment, regular maintenance for major equipment, and maintenance after event for general equipment. After the method was applied, the fault rate of second half of 2016 year was decrease 30% compared with same time of 2015 year. The total cost of maintenance of 2016 year decreased 10% compared with that of 2015 year. And the satisfaction of clinical department for department of equipment was enhanced.Conclusion: The AHP is applied to classified manage medical equipment and maintain them as weight of factor. This method has resolved many problems on maintenance of equipment, such as confused primary and secondary, and formalism and so on. According to the factor weight of maintenance to manage medical equipment at classification mode, hospital can catch key point of maintenance of equipment, and the maintenance cost can be efficiently controlled, and the work efficiency and clinical service level of equipment department can be improved and enhanced.

Animals ; Autophagy ; Coronaviridae ; genetics ; pathogenicity ; physiology ; Coronaviridae Infections ; physiopathology ; virology ; Humans ; Virus Replication

Objective: To investigate the safety and effectiveness of transvenous embolization of cavernous sinus dural arteriovenous fistula with Onxy or in combination with detachable coils. Methods: Twelve patients with cavernous sinus dural arteriovenous fistula treated by transvenous embolization from February 2007 to December 2010 were analyzed retrospectively. Ten patients were treated via the inferior petrosal sinus approach, 2 were treated via the vein-superior ophthalmic vein approach. Eight patients used Onyx alone, and 4 used Onxy in combination with detachable coils. Results: Circled digit oneAngiography showed complete occlusion in 10 patients immediately after treatment, small amount of residues remained in 2 patients. Six patients were cured with Onyx embolization alone, 2 were improved, 2 were cured with Onyx in combination with detachable coils embolization, and 2 were improved. The total effective rate was 100%, the total cure rate was 66.7%, and none of the patients worsened or died. Circled digit twoTwo patients had intraoperative bradycardia, 3 had postoperative orbital ache. Circled digit threeAll patients received clinical follow-up for 6 to 32 months and no recurrent and worsened were found. Conclusion: The clinical efficacy of transvenous embolization of cavernous sinus dural arteriovenous fistula with Onxy or in combination with detachable coils is effective and safe.

International Cooperation ; Nephrology ; trends ; Pediatrics ; trends

Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols ; administration & dosage ; adverse effects ; Carcinoma, Non-Small-Cell Lung ; drug therapy ; pathology ; Cisplatin ; administration & dosage ; adverse effects ; Deoxycytidine ; administration & dosage ; adverse effects ; analogs & derivatives ; Drug Chronotherapy ; Female ; Humans ; Leukopenia ; chemically induced ; Lung Neoplasms ; drug therapy ; pathology ; Male ; Middle Aged ; Nausea ; chemically induced ; Neoplasm Staging ; Neutropenia ; chemically induced ; Remission Induction ; Taxoids ; administration & dosage ; adverse effects

Child ; China ; Chronic Disease ; Congresses as Topic ; Humans ; Kidney Diseases ; prevention & control ; Kidney Failure, Chronic ; prevention & control ; Renal Insufficiency, Chronic ; prevention & control

BACKGROUND:Some studies have demonstrated that there is a clear correlation between osteocyte differentiation and leptin. Animal experiments have also confirmed that leptin indirectly inhibits the formation of osteoblasts through the central nervous system, but it also has some influences on the anabolism in bone microenvironment of osteoblasts. OBJECTIVE:To analyze the variation of serum leptin levels in older female patients with osteopenia, and the relationship between serum leptin levels, bone mineral density and related biochemical indexes of bone turnover. METHODS: The older female patients, aged≥ 60 years, who had lived in Xinjiang Uygur Autonomous Region for more than 30 years, were selected. Among these patients, 74 had osteoporosis, 111 had osteopenia, and 191 had normal bone mass. Serum leptin levels, bone alkaline phosphatase and other indicators of the patients were detected using enzyme-linked immunoassay method. RESULTS AND CONCLUSION:Compared with the normal group, the body mass index value and leptin level were significantly lower in the osteoporosis group (P < 0.01) and in the osteopenia group (P < 0.05). The bone mineral densities of al parts of patients in the osteoporosis group were lower than those in the osteopenia and normal groups (P < 0.01), and the bone mineral density value of patients in the ostopenia group was significantly lower than that in the normal group (P < 0.01). The serum leptin levels of older female patients with osteoporosis were significantly positively correlated with the bone mineral density value of the anteroposterior lumbar spine and the left hip bone (r=0.870,r=0.468,P < 0.01). The serum leptin levels of older female patients with osteopenia were significantly positively correlated with the bone mineral density value of the anteroposterior lumbar spine and the left hip (r=0.477, r=0.467,P < 0.01). The serum leptin levels of older female patients with osteoporosis were significantly positively correlated with body mass index (r=0.502,P < 0.01). These results suggest that reduced levels of serum leptin may play an important role in the pathogenesis of osteoporosis and osteopenia in older female patients in Xinjiang Uygur Autonomous Region, China.

BACKGROUND:Studies have shown that there is a certain correlation between blood lipid levels and bone mineral density in postmenopausal women, but their correlation in men is an open question, which has been less reported. OBJECTIVE:To investigate the relationship between blood lipid levels and bone mineral density in Han and Uygur men with hypertension in Urumqi of Xinjiang Uygur Autonomous Region, as wel as correlation of blood lipid levels with osteoporosis and osteopenia and difference between ethnics. METHODS: A total of 193 male patients with hypertension were categorized into Uygur (n=73) and Han (n=120) groups. Each group was subdivided into osteoporosis or osteopenia group and non-osteoporosis group. Bone mineral density and blood lipid level were analyzed and compared between groups. The correlation between osteoporosis and risk factors was analyzed using logistic regression method. RESULTS AND CONCLUSION:In Uygur hypertension men with osteoporosis or osteopenia, total cholesterol level was positively correlated with the bone mineral density of the femoral neck (r=0.43,P=0.01) and Ward's area (r=0.42, P=0.01); while there were no relationships between blood lipid levels and bone mineral density in Han hypertension men. When a Logistic regression analysis was performed, only total cholesterol level was found to be associated with the presence of osteoporosis or osteopenia after adjustment for body mass index, age and ethnics (OR=1.48,P=0.03). The blood lipid level is associated with bone mineral density in Han and Uygur men with hypertension from Urumqi of Xinjiang Uygur Autonomous Region, which can affect the presence of osteoporosis.

Study of traditional Chinese medicine (TCM) syndromes is a key to the research of TCM modernization, and the core is the classification and diagnostic criteria of syndromes. The purpose of this article is to review the usage of classification algorithms of data mining in TCM syndrome researches, and comprehensively analyze the main features of algorithms and their applications. The appropriate classification algorithm should be chosen according to different research purposes. Rough sets and cluster analysis are suitable for exploratory research without requiring a prior knowledge. Fuzzy sets theory, neural networks and decision tree are suitable for syndrome diagnostic criteria research when the classification goal is clear, because they require a prior knowledge. Among them, fuzzy sets theory could be used in combination with other classification algorithms. Thus, some new methods such as fuzzy clustering, fuzzy rough sets or fuzzy decision tree might be more suitable for TCM algorithm classification research. It is suggested that some novel classification algorithms need to be developed to fit the condition of TCM syndrome, based on the interdisciplinary theories and technologies.