2.Progress in mitochondrial nephropathy.
Chinese Journal of Pediatrics 2014;52(7):503-505
Alkyl and Aryl Transferases
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genetics
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Child
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DNA, Mitochondrial
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genetics
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Fibroblasts
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metabolism
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Glomerulosclerosis, Focal Segmental
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diagnosis
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drug therapy
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genetics
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Humans
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Kidney Diseases
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diagnosis
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drug therapy
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genetics
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Mitochondrial Diseases
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diagnosis
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drug therapy
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genetics
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Mutation
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Nephrotic Syndrome
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diagnosis
;
drug therapy
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genetics
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Protein Kinases
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genetics
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Ubiquinone
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analogs & derivatives
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biosynthesis
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deficiency
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therapeutic use
3.Introduction of European Association of Urology/European Society for Paediatric Urology guidelines on urina-ry tract infection in children
Chinese Journal of Applied Clinical Pediatrics 2016;31(5):337-340
Urinary tract infection(UTI)is common in children. Among the children with UTI,some children at high risk will develop renal scarring that may lead to end stage renal disease. Accurate diagnosis and appropriate treat-ment is very important. However,controversy on diagnosis and treatment of UTI still exists. European Association of Urology/ European Society for Paediatric Urology delivered new guideline for diagnosis and treatment of children with UTI in 2015.
10.Clinical application of combined detection of HE4 and CA125 in patients with endometriosis
Na LUO ; Xinghua HUANG ; Xingrong ZHONG ; Wanting ZHONG ; Xiaoming GUAN
International Journal of Laboratory Medicine 2015;(14):2075-2076
Objective To investigate the application value of single or combined detection of HE4 and CA125 in the differentia‐tion diagnosis of endometriosis .Methods The detection results of serum HE4 and CA125 levels in 105 cases of patients with ovari‐an endometriosis (endometriosis group) ,53 cases of patients with (ovarian malignant group) tumor and 64 healthy women undergo‐ing the healthy physical examination(control group) were performed the retrospective and statistical analysis .Results The positive rates of serum HE4 in the endometriosis group ,ovarian malignant tumor group and control group were 57 .1% ,90 .6% and 12 .5%respectively with statistically significant difference among them (P< 0 .05) .The positive rates of serum CA125 in the above 3 groups were 44 .8% ,92 .5% and 14 .0% respectively ,and the differences were statistically significant(P<0 .05) .(3)The sensitivity and specificity of 70 pmol/L≤ HE4<150 pmol/L for diagnosing endometriosis were 57 .14% and 53 .86% respectively ,which of 35 U/mL≤CA125<150 U/mL for diagnosing endometriosis were 44 .76% and 61 .24% .But the sensitivity and specificity of their combined detection were 70 .32% and 60 .38% .There were statistically significant differences of sensitivity and specificity among single and combined detecion of HE4 and CA125(P<0 .05) .Conclusion Serum HE4 and CA125 levels are significantly elevated in the patients with endometriosis ,their combined detection could further raise the sensitivity for diagnosing endometriosis .