1.Application of Motor Imagery Therapy in Stroke (review)
Chinese Journal of Rehabilitation Theory and Practice 2009;15(11):1032-1033
Motor imagery therapy is based on the theory of plasticity in the central nervous system. Movement with imagery improved reconstruction of damaged motor conduction pathway, and made restoration of central nervous system. Motor imagery adapts to recovery mode of stroke, and was proved to be effective on motor function when applied with physical therapy for stroke patients. This article would review its background, mechanisms, Methods and effects, etc.
2.The validity and responsiveness of the Chinese version of the mini-Balance Evaluation Systems Test
Changxiang CHEN ; Yunlong WANG ; Suhui MA ; Na DOU ; Dan LI
Chinese Journal of Physical Medicine and Rehabilitation 2015;37(1):16-19
Objective To evaluate the validity and responsiveness of the Chinese version of the miniBalance Evaluation Systems Test(mini-BESTest).Methods A total of 208 stroke patients were evaluated by 2 professionals using both mini-BESTest and Berg balance scale (BBS).All data were analyzed using Pearson correlation,t-test and descriptive statistical analysis.Results Significant correlation was observed between each entry of the mini-BESTest and its domain,with correlation coefficients ranging from 0.78 to 0.93 (P < 0.05).The scores of whole assessment and the three related domains were significantly correlated between mini-BESTest and BBS results,the correlation coefficients ranging from 0.68 to 0.87 (P < 0.05).After 2 weeks of treatment,there was significant improvement in each domain and in the total assessment score (P < 0.05).No floor or ceiling effects were observed in the total mini-BESTest scores,but there was a slight ceiling effect in the anticipatory and sensory orientation domains,and a slight floor effect in the reactive postural control domain.Conclusion The mini-BESTest has good validity and responsiveness,and can be applied to evaluate patients after stroke.
3.Systematic review of intrapleural fibrinolytic agents in treatment of childhood empyema
Wenjie DOU ; Jianjiang ZHANG ; Peipei SHI ; Na WANG ; Huiqin ZENG
Chinese Journal of Applied Clinical Pediatrics 2015;30(7):541-544
Objective To evaluate the efficacy and safety of intrapleural fibrinolytic agents in the treatment of childhood empyema.Methods The data from China National Knowledge Infrastructure (CNKI),Chinese BioMedical (CBM),PubMed,VIP Database and Cochrane library were reviewed.Randomized control trials by using intrapleural fibrinolytic agents to treat childhood empyema were included.Two reviewers independently extracted the data from the eligible studies and evaluated the quality of the included studies.Meta-analysis was performed for the results of homogeneous studies using RevMan 5.2 software,while others analyzed descriptively.Results Five randomized control trials involving 248 children with empyema were included.Meta-analysis was not made in all of the indexes because of apparent heterogeneity and limited data.Two trials were compared which involved 98 patients receiving fibrinolytic agents or 9 g/L saline.The results suggested that fibrinolytic agents shortened the length of hospital stay and reduced complication(all P < 0.05),but no significant differences were found between the 2 groups in the effective rate,duration of fever and pleural effusion amount(OR =3.61,95% CI 0.84-15.49,P > 0.05).Three trials involving 150 patients compared fibrinolytic agents and video-assisted thoracoscopic surgery (VATS).The data suggested that no significant differences were found between 2 groups in the effective rate (OR =0.70,95 % CI 0.30-0.61,P > 0.05),but fibrinolytic agents cost less (P < 0.05).The adverse drug reactions to intrapleural fibrinolytic agents were mild to moderate,and well tolerated.Conclusions The findings suggest that intrapleural fibrinolytic agents in the treatment of childhood empyema is safe and effective,especially in encapsulated effusion.Compared to 9 g/L saline,it can shorten the length of hospital stay and reduce complication.Compared with VATS,the curative effect is similar,while intrapleural fibrinolytic agents are economic.
4.Investigation into a new professional English teaching system for postgraduate dental students
Lei DOU ; Na WU ; Jia LIU ; Deqin YANG
Chinese Journal of Medical Education Research 2016;15(6):610-613
In view of the weakness of the teachers' strength, students' lack of interest and the lack of unity of teaching materials in the foreign language teaching, Oral Medicine College of Chongqing Medical University carried out the reform to the professional foreign language courses in the postgraduate education period by strengthening the preparation of special teaching materials, reinforcing teaching staff construction, reforming teaching methods and creating a learning environment. The results of teaching assessment by students and peer-reviewers show that reform has achieved good results, and aiming at the problems in the teaching practice we also put forward such improvement measures as strengthening the student-centered teaching method, promoting new teaching methods and optimizing curriculum assessment programs.
5.Application of Clinical Performance Instrument in Undergraduate Teaching in Rehabilitation Therapy
Suhui MA ; Dan LI ; Na DOU ; Qingwen WU
Chinese Journal of Rehabilitation Theory and Practice 2013;19(8):788-790
Objective To explore the effect of American Physical Therapy Association's clinical performance instrument on undergraduate teaching in rehabilitation therapy. Methods The theory and practice lessons of Grade 2007 and 2008 were chosen. Grade 2007 adopted traditional teaching combined with 30% problem-based learning, and Grade 2008 adopted clinical performance instrument by American Physical Therapy Association. Results and Conclusion The ability to handle the whole medical standard was better in Grade 2008 than in Grade 2007 (P<0.001). And the function evaluation, treatment of implementation, the outcome assessment, guidance after discharge and preventive measures were better in Grade 2008 than in Grade 2007 (P<0.05).
6.Effects of Somatic Sense Interactive Game on Balance and Walking Function in Stroke
Na DOU ; Dan LI ; Suhui MA ; Changxiang CHEN
Chinese Journal of Rehabilitation Theory and Practice 2014;20(1):66-69
Objective To research the effects of somatic sense interactive game Kinect on balance and walking function in stroke patients.Methods 40 patients with stroke were divided into control group (n=20) and experimental group (n=20), who accepted conventional rehabilitation and additional somatic sense interactive game Kinect. They were evaluated with gait analysis, Berg Balance Scale, Holden Walking Function Rating Scale and Barthel Index before and after treatment. Results Both groups improved in all the indices after 4 weeks of treatment (P<0.001), and improved more in the experimental group than in the control group (P<0.05). Conclusion The somatic sense interactive game Kinect could further improve the balance and walking function of stroke patients.
7.Cultivation of students' clinical thinking and practice skills in undergraduate teaching of rehabilitation therapy
Suhui MA ; Dan LI ; Na DOU ; Changxiang CHEN
Chinese Journal of Rehabilitation Theory and Practice 2012;18(12):1178-1180
目的探讨以问题为基础的教学法(PBL)和康复病例实验报告两种教学法在运动疗法(PT)模块中的应用效果。方法选择2008 级四年制康复治疗学专业本科学生88 名,1 班采用PBL教学模式,2 班采用理论、实践相结合的康复病例采集与书写模式,采用自制教学效果评价表、学生实习跟踪调查进行评价。结果两班学生综合素质和分析问题的能力均有提高。2 班在观察能力、动手能力、理论与实践结合、疾病信息采集、分析判断能力、临床适应能力、服务态度与同情心、康复评定的全面性等方面好于1 班(P<0.05),1 班在信息技术利用方面优于2 班(P<0.05)。结论融基础知识、专业知识、临床实践于一体,以书写康复病例为学科综合,培养学生以功能障碍为纲的临床思维,可以提高学生的动手能力、分析判断能力、医患沟通能力和临床适应能力,做到了课堂-见习-实习密切连接。
8.BrainHQ visual training can improve the memory of stroke survivors
Jing WANG ; Ronghua MAO ; Changxiang CHEN ; Shuxing LI ; Min ZHANG ; Na DOU
Chinese Journal of Physical Medicine and Rehabilitation 2016;38(8):576-579
Objective To investigate the efficacy of BrainHQ visual training in rehabilitating memory function among stroke survivors.Methods Sixty stroke patients with memory disorders were recruited from the rehabilitation center of Tangshan Workers' Hospital.They were randomly assigned to a control group or an intervention group,each of 30.Both groups accepted conventional rehabilitation,while the intervention group was additionally given BrainHQ visual training five times a week for 30 minutes,lasting four weeks.Before and after the treatment,both groups completed the Rivermead behavioral memory test.Results After the 4 weeks of treatment,the average scores in recalling full names,recalling hidden items,recalling appointments,recognizing pictures,recognizing faces,recalling a story immediately,delayed story recall,recalling a route promptly,delayed route recall and the average total score in both groups were all significantly higher than before the treatment.The treatment group scored significantly better than the control group except in recalling hidden items,and recognizing faces and pictures.Conclusion BrainHQ visual training can improve the memory of stroke survivors.
9.Changes and clinical significance of serum cortisol and adrenocorticotrophic hormone levels in children with steroid-sensitive nephritic syndrome
Jianjiang ZHANG ; Na WANG ; Miao WANG ; Shuqin FU ; Wenjie DOU ; Peipei SHI
Chinese Journal of Applied Clinical Pediatrics 2015;30(5):351-354
Objective To investigate the changes in serum cortisol and adrenocorticotrophic hormone(ACTH) levels in children with steroid-sensitive nephritic syndrome (SSNS) and the clinical significance of intervention.Methods According to whether a child with SSNS would relapse,48 children with SSNS were divided into non-recurrence group(n =19) and recurrence group(n =29),at the same time 14 age-matched healthy children were enrolled as the healthy control group.Serum cortisol and ACTH were measured in patients with SSNS by using electrochemiluminesence methods.In recurrence group,methylpredisolone or methylprednisolone combined with ACTH injection therapy was used on 15 patients with their serum cortisol and ACTH below normal.Results Before standard glucocorticoid treatment,the serum levels of cortisol and ACTH had no difference among 3 groups (all P > 0.05).By the end of remission phase,the serum levels of cortisol and ACTH in recurrence group were statistically lower than those of the non-recurrence group[(113.03 ± 80.02) μg/L vs (251.54 ± 185.05) μg/L,t =-2.925,P < 0.05 ; (12.81 ± 10.14) ng/L vs (23.53 ± 12.05) ng/L,t =-0.885,P < 0.05].Eight to 12 weeks after being adjusted,the serum level of cortisol and the average monthly time of recurrent were both significantly improved in 15 abnormal children in recurrence group [(168.90 ± 133.43) μg/L vs (73.62 ± 58.04) μg/L,t =3.016,P < 0.05 ; (0.09 ± 0.08) times vs (0.35 ± 0.11) times,t =-7.560,P <0.05],but as to the serum level of ACTH,there was no significant difference in abnormal children in recurrence group [(14.05 ± 10.99) ng/L vs (8.72 ± 4.11) ng/L,t =1.991,P > 0.05].Conclusions The concentrations of serum cortisol and ACTH can reveal the risk of recurrence for children with SSNS to some extent,and effective intervention can reduce the recurrence rate and shorten the course of disease.
10.Relationship between Homer1a and nerve cell loss in hippocampus after severe diffuse brain injury in rats
Jianmin LI ; Yaning ZHAO ; Rongli MA ; Na DOU ; Changxiang CHEN ; Shuxing LI ; Pan ZHANG
Journal of Medical Postgraduates 2014;(8):797-801
(DBI) in rats by observation on the changes of Homer 1a expression and apoptotic nerve cells . Methods Spraque-Dawlley(SD) rats were randomly ( random number ) divided into control group and severe DBI group .DBI rat model was established according to the de-scription of Marmarou′s diffused brain injury .No injury was done on control group .The changes of neuron pathology were observed by light microscopy and electron microscope .The expression of Homer1a was observed by immunohistochemistry and western blot .The quan-tity of apoptotic cells was measured by terminal deoxynucleotidyl transfernase medicated nick end labeling ( TUNEL) method. Results The death rate of rats in severe DBI group was 49.3%.Compared with the control group , the ultrastructures in hippocampal neurons in-cluding organelle , axonal and capillary were damaged seriously after injury , the survival rate of nerve cells decreased significantly at 1 h after injury ([99.4 ±0.6]%vs [94.4 ±5.6]%, P<0.05), and peaked at 72 h ([99.2 ±0.8]%vs [54.7 ±33.8]%, P<0 .05) in DBI group.The expression of Homer1a protein increased significantly at 1 h after injury(0 .136 ±0.024 )and peaked at6 h(0.178 ± 0.028) and maintained to 24 h (0.176 ±0.027), while decreased at 48 h (0.145 ±0.02)and 72 h (0.117 ±0.012) in DBI group;the expression of Homer 1a was obviously higher at each time point in DBI group than that in control group (P <0.05).The apoptoticindex of TUNEL positive cells increased at 6 h and demonstrated significant difference at 72h in comparison to control group ([41.78 ±3 .96]%vs [1.92 ±0.22]%, P<0.05).The correlation analysis indicated that Homer1a expression from 1~24 h and 24 h~72 h was related to the survival rate of nerve cells ( r=-0.726, P<0.05; r=0.842, P<0.05) and the quantity of TUNE positive cells(r=0.738, P<0.0;5 r=-0.898, P<0.05). Conclusion The dynamic expression of Homer1a in hippocampus after severe DBI can reflect nerve cell loss.