Objective To compare the quality of life at baseline and at 3 months after coronary artery bypass grafting(CABG) and investigate the related risk factors. Methods The prospective study included 121 consecutive patients reaching inclusion criteria and undergoing CABG between June 2009 and May 2016. Health status survey was measured with short form-36(SF-36)at baseline and at 3 months after CAGB. Change of quality of life and influencing factors and quality of life were analyzed. Results Eight domains including physical functioning ,role-physical ,bodily pain,general health,vitality,social functioning,role-emotional and mental health and two component summaries including physical component summary(PCS)and mental component summary (MCS)of SF-36 were significantly improved at 3 months following CAGB(all P<0.01). Moreover,advanced age, women,diabetes mellitus,assisted ventilation time,hospital stay and use of t-PA were relative to the PCS after CAGB. Conclusions The findings demonstrate quality of life is significantly improved at 3 months post CAGB. Advanced age,underlying disease,serious disease,women and lower PCS score prior to CAGB are linked with low PCS after CAGB.

Objective To analyze the colorectal cancer screening of community residents in Pudong New Area in Shanghai and provide reference for the promotion and strategy optimization of colorectal cancer screening programs. Methods Residents aged 50-74 years in the colorectal cancer screening project of Pudong New Area in Shanghai from 2013 to 2023 were recruited in this analysis. The situation of primary screening and colonoscopy in the community was described, and results of different age groups in primary screening and colonoscopy surveys were evaluated. Chi-square test was used to determine differences between groups. Results From 2013 to 2023, 907 030 residents were screened in Pudong New Area, of which 183 724 residents were positive, and the positive rate was 20.3%. The positive rate was the lowest in the 50-54 age group and the highest in the 70-74 age group. The positive rate was higher in men than in women. The overall colonoscopy rate was 27.1%, with the highest rates in the 50-54 age group in men and the 55-59 age group in women, respectively. The participation rate of colonoscopy increased with the increase of the year. A total of 19 094 cases of intestinal lesions were found by colonoscopy. Among these lesions, 1 147 cases were colorectal cancer, accounting for 6.0%, and the population detection rate was 126.5/100 000. In addition, 4 751 cases of precancerous lesions were found, accounting for 24.9%, and the detection rate was 523.8/100 000. Conclusion Colorectal cancer screening improves the detection rate of precancerous lesions and early cancer and is of great significance for reducing the incidence and mortality of colon cancer. Measures should be taken to optimize the screening strategy based on age differences and increase the participation rate of primary screening and colonoscopy to achieve the best effect of local colorectal cancer prevention and treatment.