1.Some result of the study of relationship between spread of animals containing of plague and climate change at the ugalz mountains
Sumiyabazar N ; Munkhbat O ; Batjav D ; Delgermaa T
Mongolian Medical Sciences 2013;164(2):11-18
Climate: Studies show that it is get warmer 2.10C in Mongolia in last 40 years. It influences ecology and decreased ecology event, succession action in ecosystem. It is interesting to study how climate change damage animal’s biology and ecology. The survey on changing ecology is rare conducted in Mongolia. Year average air temperature in Govi-Altai province got warmer 1.20C in last 30 years. Monitoring agency for meteorology and environment of Govi-Altai aimag summarized air temperature 1980-2009 (4-9 months) and it is got warmer 2.00C in Tonkhil soum.Plants: According to our research, at the above sea level around 2229-2600m dry steppe, at a.s.l 2601-2800m in steppe and water-meadow steppe at a.s.l 2801m high mountain steppe, zone plants grow. At the report of research for motion and episodic in epicenter of the marmot plague (1987-1991) aspect of plants figure by J.Batbold warm weather influence plants grow at around 100m.Animal spreading: In 1987-1991 M.sibirica spread almost part, S.erythrogenus above sea level 2300m in Ugalz mountains. Places where marmots live don’t have any marmots such as Alagiin hooloi, number of marmot is dramatically decreasing last years. It is related to climate change and hunting. Plants are changed due to influence climate animals in desert, dry steppe spread in Ugalz mountains and above sea level 2550m S.erythrogenus are according to the research, E.luteuse are spreading in front area of the Ugalz mountains, S.erythrogenus are spreading back of the Ugalz mountains.
2.THUNDERBEAT IN USE THYROID SURGERY
Tumur-Ochir Ch ; Shim Woo Jeong ; Munkhbat D ; Baasanjav D ; Bayarkhuu A ; Enkhbat G ; Erdene-Bolor B ; Naranbat L
Journal of Surgery 2016;19(1):64-69
Introduction: Last Decades, Date by date
medical developments providing friendly,
high-efficiency treatment equipment and
services in developed countries are working
toward an advanced, as our country medical
services are trying to that country’s technology
has been introduced. In our country every
day there is only surgical care necessary to
endocrine gland disorders, including most
common thyroid surgery. It is open and
robotic assistant endoscopic surgery in the
world. But robotic assistant endoscopic
surgery is too expensive and impossible in
our country. Thus we chose Thunderbeat
for open thyroid surgery in especially huge
enlarged goiter and vascularized goiter to try
prevent bleeding, recurrent laryngeal nerve
palsy and post operation hematoma and
other complications
Thunderbeat is new generation instrument
combines an advanced bipolar clamp to the
existing ultrasonic cutter.
Materials and Methods: M 51-years-oldwoman
was admitted to Mongol Hyundae
hospital because of front of neck pain, multi
nodular goiter, tachycardia, sweaty and not
controlling emotion.
Anamnesis: She diagnosed to
Thyrotoxicosis in 2005 and she took
medicine last ten years but not controlling
that poisoning. Status locals: Huge enlarged
goiter in front of her neck
Treatment plan:
1. Preoperative Preparation
2. Operation: Open total thyroidectomy
3. Medicine
4. Wound dressing
5. Observation
We did operation after day of admission
day, Patient is placed in a Semi erect position
with a folded sheet underneath the shoulders
so that the head is sharply angulated backward
on the multifunctional surgical table under
general anesthesia. We used thunderbeat
from muscular to all procedures, dissection
both thyroid gland and isthmus after Kocher
skin incision and sub skin tissue dissected.
There is no complication while procedure
and post operation days
Result: Nodular hyperplasia of thyroid
gland with focci of micro adenomatous
change
Conclusion: Thunderbeat in use open
thyroid surgery first outcomes blood loss
than 30ml, no injury of recurrent laryngeal
nerve and no penetration ligament of Berry
while procedure, second outcomes no
hematoma, painless, wound healing process
faster and short time hospitalization.
3.Bladder cancer risk factors in Mongolians
Baasansuren S ; Shiirevnyamba A ; Myagmarsuren P ; Batmunkh G ; Amarsaikhan S ; Bayan-Undur D ; Munkhbat B
Mongolian Medical Sciences 2015;173(3):7-12
BACKGROUND: Bladder cancer is a cancer of significant morbidity and mortality in the worldwide. It is the second most common urological cancer in Mongolia. It is important to understand the risk factors of bladder cancer.We evaluated the association of smoking, alcohol intake, body mass index and other potential risk factors with bladder cancer incidence in Mongolians.MATERIALS AND METHODS: We analyzed data from a case-control study (116 histologically confirmed bladder cancer cases and 300 cancer-free healthy, age, gender-matched controls). All participants signed the consent form andfilled out the structured questionnaire including cigarette smoking, BMI, chronic urinary disease andalcohol drinking etc. Using logistic regression we estimated the covariate-adjusted odds ratio (OR) and95% confidence interval (CI) of the associations.RESULTS: Mean age of the patients with bladder cancer was 56±10.5 years and 79.3% male and 20.7% female.Cigarette smoking, history of urinary tract diseases and body mass index were associated with an increased risk of bladder cancer OR 6, 48 (95% CI 1, 61-1, 70), OR 80 (95% CI 1, 48-1, 93) and OR=9.8 (95% CI 2.32-2.91) respectively but not alcohol drinking OR 0, 26 (95% CI 1, 56-1, 66).CONCLUSIONS: The results suggest that cigarette smoking, history of urinary tract diseases and body mass indexincreased risk of bladder cancer in Mongolian patients.
4.About Mongolian blue spot
Bujin E ; Lkhaasuren N ; Batchimeg B ; Tselmen D ; Oyungerel G ; Munkhtuvshin N ; Munkhbat B
Mongolian Medical Sciences 2014;168(2):106-111
Mongolian blue spots are birthmarks that are present at birth and their most common location issacrococcygeal or lumbar area. There are macular and round, oval or irregular in shape. Lesionsmay be single or multiple. They usually spontaneously regress and disappear during childhood.The prevalence of Mongolian blue spots varies among different ethnic groups according to theoverall depth of pigmentation. Mongolian blue spots are common among Asian, East Indian, andAfrican races, but rare among Caucasian and other races. Mongolian blue spot is a congenital,developmental condition exclusively involving the skin. Mongolian blue spot results from entrapmentof melanocytes in the dermis during their migration from the neural crest into the epidermis. Thismigration is regulated by exogenous peptide growth factors that work by the activation of tyrosinekinase receptors. It is postulated that accumulated metabolites such as GM1and heparin sulfatebind to this tyrosine kinase receptor and lead to severe neurologic manifestations and aberrantneural crest migration.
5. The evaluation of immunosuppressive regimens in kidney transplant Mongolian recipients
Sarantsetseg J ; Narmandakh G ; Bolortuya KH ; Oyungerel TS ; Batbaatar G ; Munkhbat B ; Nyamsuren D
Health Laboratory 2015;4(1):8-14
Background:However kidney transplantation has being performed in Mongolia since 2006, because of pre-transplant ensitization, ABO incompatibility, hepatitis B and C virus activation many patients are taken kidney transplantation in abroad. The transplantation centers use own immunosuppressive regimens.Objective:Our aim was to assess the immunosuppressive regimens efficacy and toxicity in kidney transplant Mongolian recipients.Material and Methods:We analyzed data from 96 adult kidney transplant recipients who had taken kidney transplantation in different transplant centers from August 2006 through January 2014. There were 3 kinds of regimens Group I Simulect induction with standard triple /FK506/CyA+MMF/AZA+steroid/, Group II Campath-1H induction with CNI monotherapy and Group III Campath-1H induction with standard triple /FK506/CyA+MMF/AZA+steroid/. We retrospectively collected the post-transplant first two year serum creatinine. The study was performed in 2014. The questionnaire was taken and blood samples collected for determination of tacrolimus through level and for other laboratory tests. The primary end point was the first two years serum creatinine, the secondary end points included rejection episodes, blood through level of tacrolimus and some laboratory findings.Results:The post-transplant first two years serum creatinine levels were significantly different in 3 groups. Group III showed similar results compared to Group I. There was not enough data of biopsy proven acute rejection episodes however group II said more rejections occurred. However participants said that rejection occurred in 15 (15.6%) biopsy was done only 3 (3.1%) cases. Blood through level of tacrolimus was significantly different in three groups. Some laboratory findings showed different between three groups.Conclusion:A regimen of Campath-1H induction with CNI monotherapy (Group II) may be advantageous for short-term renal function and cost effective but there were more rejection complications and increased creatinine. The regimen of Campath-1H induction with standard triple (Group III) may be advantageous for long-term renal function, allograft survival, but there should consider about infection complications and polycythemia. Simulect induction with standard triple could be best choice but transplantations were performed in experienced centers. The study enrolled few cases and cases which were performed at the beginning of transplant program so many things could influence on the result. The study was compared beginner transplant center with experienced centers. Longitudinal cohort study needed in the future.
6. THUNDERBEAT IN USE THYROID SURGERY
Tumur-Ochir CH ; Shim Woo Jeong ; Munkhbat D ; Baasanjav D ; Bayarkhuu A ; Enkhbat G ; Erdene-Bolor B ; Naranbat L
Journal of Surgery 2016;19(1):64-69
Introduction: Last Decades, Date by datemedical developments providing friendly,high-efficiency treatment equipment andservices in developed countries are workingtoward an advanced, as our country medicalservices are trying to that country’s technologyhas been introduced. In our country everyday there is only surgical care necessary toendocrine gland disorders, including mostcommon thyroid surgery. It is open androbotic assistant endoscopic surgery in theworld. But robotic assistant endoscopicsurgery is too expensive and impossible inour country. Thus we chose Thunderbeatfor open thyroid surgery in especially hugeenlarged goiter and vascularized goiter to tryprevent bleeding, recurrent laryngeal nervepalsy and post operation hematoma andother complicationsThunderbeat is new generation instrumentcombines an advanced bipolar clamp to theexisting ultrasonic cutter.Materials and Methods: M 51-years-oldwomanwas admitted to Mongol Hyundaehospital because of front of neck pain, multinodular goiter, tachycardia, sweaty and notcontrolling emotion.Anamnesis: She diagnosed toThyrotoxicosis in 2005 and she tookmedicine last ten years but not controllingthat poisoning. Status locals: Huge enlargedgoiter in front of her neckTreatment plan:1. Preoperative Preparation2. Operation: Open total thyroidectomy3. Medicine4. Wound dressing5. ObservationWe did operation after day of admissionday, Patient is placed in a Semi erect positionwith a folded sheet underneath the shouldersso that the head is sharply angulated backwardon the multifunctional surgical table undergeneral anesthesia. We used thunderbeatfrom muscular to all procedures, dissectionboth thyroid gland and isthmus after Kocherskin incision and sub skin tissue dissected.There is no complication while procedureand post operation daysResult: Nodular hyperplasia of thyroidgland with focci of micro adenomatouschangeConclusion: Thunderbeat in use openthyroid surgery first outcomes blood lossthan 30ml, no injury of recurrent laryngealnerve and no penetration ligament of Berrywhile procedure, second outcomes nohematoma, painless, wound healing processfaster and short time hospitalization.
7.Study of hereditary neuropathy in the large kindreds of Gobi-Altai province
Batchimeg B ; Bilegtsaikhan TS ; Oyungerel G ; Tselmen D ; Erdenechimeg YA ; Oyuntsetseg М ; Baasanjav D ; Munkhtuvshin N ; Munkhbat B
Mongolian Medical Sciences 2012;161(3):20-24
The purpose of the present study was to elucidate genealogical and clinical features of hereditary neuropathy in the several kindreds of Gobi-Altai province.Materials and Methods: In the present study, we investigated five kindreds originated from Bayan-Uul sum, Gobi-Altai province on the basis of previous surveys. Each participant was enrolled for genealogical and neurological examinations according to specific questionnaire. We also collected biological samples for further genetic study. Genomic DNA was isolated from biological samples, and quantitative analysis of DNA was determined by spectrophotometer and Picogreen assays.Results: Twenty members from five kindreds were investigated. Genealogical analysis revealed that there is a linkage between two kindreds within the families enrolled into study, whereas no association was revealed among the other pedigrees. As a phenotype of the hereditary neuropathy, the clinical features were inherited in every generation, and the inheritance was not dependent on the gender. In neurological examination, age of hereditary neuropathy onset was detected as follows. The clinical features appeared in the first decade of life in 4 patients, in the second decade of life in 5 patients, and for the other members the disease started in the age of over 20 years. Common clinical features of hereditary neuropathy were characterized by hypomimic- and mask shape face, muscular atrophy of upper and lower limbs, and pes cavus. Interestingly five female patients had similar gynecological problems. Conclusions:1. The hereditary neuropathy exists in the kindreds of Bayan-Uul sum, Gobi-Altai province and the type of inheritance could be categorized as autosomal dominant.2. Onset of hereditary neuropathy disease was started mostly in the second decade of life. Common clinical features of hereditary neuropathy were characterized by hypomimic- and mask shape face, muscular atrophy of upper and lower limbs, and pes cavus. Apart from general clinical features, the specific complications related to metabolic disorders and pregnancy was detected.
8. Study of growth gene of Mongolians
Enkhdelger M ; Oyungerel G ; Tselmen D ; Batchimeg B ; Bujin E ; Avirmed A ; Munkhbat B ; Amgalanbaatar D ; Munkhtuvshin N
Health Laboratory 2013;1(1):35-52
9.STUDY OF “AKHIZUNBER” SOLUTION FOR THE TREATMENT OF INFLAMMATORY ORAL STOMATITIS
Urjinlkham J ; Batsuuri M ; Bulgan Ch ; Sapaar B ; Davaadagva D ; Munkhbat S ; Oyunbat B ; Choijamts G ; Bayarchimeg B ; Oyun-Enkh P ; Oyunkhishig Kh ; Nyamsuren E
Innovation 2018;12(4):8-11
ABSTRACT.
Recurrent aphthous stomatitis, or RAS, is common oral disorder of uncertain etiopathogenesis for which only symptomatic therapy is available. This article reviews the current clinical features of RAS among study patients and the result of therapeutic effects of the herbal preparation Akhizunber. Over the past four years we have treated 61 RAS patients with different clinical forms by herbal preparation Akhizunber or Alumekatin. The distribution of clinical forms RAS RAS among study patients were minor aphthae -75.4%, major aphthae -16.4% and herpetiform ulcers -8.2% respectively. The healing time of treated Akhizunber was in minor aphthae -9.28±4.82 days, major aphthae -14 days and herpetiform ulcers -12 days. Of the total study participants, the patients treated by Akhizunber reported a rapid and complete recovery from RAS during treatment compared with treated patients by Alumekatin. Treatment with herbal preparation Akhizunber can be effective for patients suffering from RAS in any clinic form, regardless of their ulcer number and size.
10.Impact of HLA-A-B-DR matching in kidney transplantation: Graft and patient survival in 5-year experiences
Sarantsetseg J ; Oyunbileg B ; Odgerel D ; Narandulam B ; Batbaatar G ; Munkhbat B
Health Laboratory 2019;9(1):5-11
Background:
Kidney transplantation has being performed in Mongolia since 2006. However
there is currently no published data available on long-term graft and patient survival.
Objective:
Our aim was to assess the long-term graft and patient survival rate correlation with HLA-A-B-DR matching.
Methods:
We retrospectively analyzed data from 70 adult kidney transplants performed at
our hospital from August 2006 through January 2014. The data was retrospectively collected
from patient files, including characteristics of the recipient and donor, post transplant features
and HLA-A-B-DR DNA based typing results. The Kaplan-Meier method was used to analyze
graft and patient survival.
Results:
The mean patient follow-up period after kidney transplantation was 39,6±25.9
months, and the mean kidney graft follow-up period was 36.6±23.7 months for 70 cases.
Overall graft and patient survivals were 52 (74.3%) and 60 (85.7%) respectively in 70 cases.
Five-year graft and patient survivals were 23 (67.6%) and 29 (85.3%) respectively in 34
cases. The group with four to six mismatched were found to have a significantly lower 3 and
5-year graft and patient survival (71%; 35%); (80%; 40%) compared to 0 to 1 mismatched
group (100%) (p=.030; p=.015). Furthermore we analyzed the association of HLA matching,
immunosuppressive therapy and long-term graft survival. We selected CNI mono-therapy
group for long-term survival analysis and observed a similar pattern. In mono-therapy group,
the group with four to six mismatched were found to have a significantly lower 3 and 5-year
graft and patient survival (75%; 30%); (65%; 30%) compared to 0 to 1 mismatched group
(100%) (p=.037; p=.001).
Conclusion
The results showed that graft and patient survival rates were lower compared
with results from established centers. Statistically highly significant effect of HLA matching on
kidney graft and patient survival rates was found in our analysis. Five years after
transplantation the graft survival rate of first adult kidney transplant with 4-6MM was 65-70%
lower than that of grafts with 0-1MM. Longitudinal cohort study needed in the future to exhibit
an improved transplantation outcome.