This report stresses on the occurrence of a rare adverse reaction to clozapine, i.e.
allergic cutaneous and visceral angioedema, in a patient with treatment resistant
schizophrenia (TRS). We report the case of a schizophrenic patient who was
resistant to treatment and developed an allergic reaction involving her skin and
gastro-intestinal system upon the commencement of clozapine. She was then
treated with a combination pharmacotherapy which left some residual symptoms.
The manifestation of allergic reactions to clozapine and its management strategies
are discussed in the paper. There is a pressing need to develop a new psychotropic
which is on par with clozapine.
Schizophrenia
;
Clozapine