1.Correlation of abdominal fat ratio with CT enhanced degree of the liver
Mujie GUO ; Yufen WU ; Qing ZHANG
Journal of Practical Radiology 2014;(7):1147-1149
Objective To evaluate the effect of abdominal fat ratio (AFR,abdominal fat volume to total abdominal volume)at the umbilical level on hepatic CT enhancement in humans.Methods We analyzed data in 87 patients (40 women and 47 men)by Pearson correlation and linear regression analysis to assess the association of patient age and AFR with adjusted maximal hepatic enhancement (aMHE,maximal hepatic enhancement divided by the dose of iodine divided by body weight)by sex.Results aMHE was positively correlated with AFR for both men and women (r=0.48 and 0.46,respectively,both P <0.01)but not patient age.Conclusion Pa-tients with more abdominal fat seem to require relatively less amount of contrast media to get the CT enhanced degree of liver similar to those with less fat.
2.Correlation between self-efficacy and fall efficacy in patients with stroke
Guo QIYUN ; Guo MUJIE ; Zhang LIN ; Guo LINA ; Li DAN ; Liu KUN
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(4):347-349
Objective To explore the relationship between self efficacy and fall efficacy in patients with stroke.Methods The falls efficacy scale-international (FES-I) and the stroke self-efficacy questionnaire(SSEQ) were applied to 300 patients with stroke.Results The FES-I score of the participants was 39.13± 16.40,the scores of the indoor activity dimension and outdoor activity dimension were (26.01 ± 11.13) and (18.33 ± 7.76),respectively.The total mean score of SSEQ was (40.11 ± 22.37),the scores of the activity function dimension and self-management dimension were (24.97± 14.40)and (15.14±8.35),respectively.FES-I scores were positively correlated with SSEQ scores (r=0.550-0.802,P<0.05).Falls efficacy could explain 34.3% and 36.8% variation amount for each dimension of self-efficacy in patients with stroke.Conclusion Falls efficacy is closely related to self-efficacy in patients with stroke.In order to improve the quality of medical care,medical staff should pay attention to the occurrences of reduction of self-efficacy and selfesteem in patients with stroke when they avoid falling during some activities.
3.Development of the Chinese version stroke self-efficacy questionnaire
Qiyun GUO ; Mujie GUO ; Lin ZHANG ; Lina GUO ; Han GAO ; Yueqin CHEN ; Kun LIU
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(3):273-275
Objective To translate the English version of the stroke self-efficacy questionnaire (SSEQ) into Chinese,and to evaluate the reliability and validity of the Chinese version of SSEQ.Methods The reliability and validity of the Chinese version of SSEQ were tested among 300 stroke patients in Jinzhou city.Data were analyzed by SPSS 17.0 software and AMOS 17.0 software.Results The Cronbach's α was 0.972,the test-retest reliability coefficient was 0.806,the correlations between items and total scale ranged from 0.729 to 0.831 (P<0.01).A two-factor model was got by exploratory factor analysis,the communalities of the items was 0.672 to 0.929,and the cunulative explained variance was 82.687 percent.The confirmatory factor analysis revealed a good model fit,and the fit indices were x2/df =1.740,GFI =0.918,AGFI =0.853,RMSEA =0.070,NFI =0.965,CFI =0.985,standardized regression weights was 0.701 to 0.984.Conclusion The Chinese version of the SSEQ is proved to be reliable and valid.It can be used to assess the self-efficacy of stroke patients in china.
4.Reliability and validity of Chinese version of the Osteoporosis Knowledge Assessment Tool in the elderly
Qiyun GUO ; Mujie GUO ; Lin ZHANG ; Pengpeng ZHAO ; Lina GUO ; Han GAO ; Kun LIU
Chinese Journal of Practical Nursing 2015;31(7):512-515
Objective To test the reliability and validity of the Chinese version of Osteoporosis Knowledge Assessment Tool (OKAT).Methods The English version of OKAT was introduced and the Chinese version was confirmed by translation,revision,retroversion and expert discussion.A sample of 400 community-living aged people were recruited to complete the OKAT (Chinese version).Internal consistency test,split-half reliability,correlation analysis,items analysis,content validity,exploratory factor analysis,confirmatory factor analysis and ROC curve were used for examination.Results The Cronbach's α of the total scale was 0.821.The split half reliability coefficient was 0.934,test-retest reliability was 0.866,inter rater reliability coefficient was 0.786,the correlations between items and total scale ranged from 0.163 to 0.542.A two-factor model containing 20 items was got by exploratory factor analysis,the cumulative contribution rate of the items was 75.528 percent.The confirmatory factor analysis revealed a good model fit.Conclusions The Chinese version of the OKAT in the elderly is proved to be reliable and valid.It can be used to assess osteoporosis for the aged people in China.
5.Effects of isokinetic training on walking ability in hemiplegic patients after stroke
Junfeng GUO ; Shunji SHEN ; Guanghu YU ; Jie LI ; Ming LEI ; Mujie LI
Chinese Journal of General Practitioners 2013;(5):387-389
A total of 60 hemiplegic patients after stroke were divided randomly into 2 groups.The control group received conventional rehabilitation training while the treatment group isokinetic training based on conventional rehabilitation training.Both groups were trained for 8 weeks.Results showed the differences of peak torque of knee flexors and extensors were significant between two groups (P < 0.01).The ratio of flexion and extension showed significant difference (P < 0.01).The treatment group was superior to control group in walking ability (P < 0.01).Therefore isokinetic training provides significant improvement in stability of knees and walking ability in hemiplegic patients after stroke.
6.Comparison of the clinical characteristics of ovarian lymphoma and ovarian cancer with bulk lymph node involvement
Feifei GAO ; Lei GUO ; Kai XUE ; Weiqi SHENG ; Wei WANG ; Mujie LI ; Zhong ZHENG ; Ziting LI
China Oncology 2017;27(4):281-286
Background and purpose: Ovarian lymphoma (OL) is usually misdiagnosed as ovarian cancer with bulk lymph node invasion (OC-BLN), and vice versa. Therefore, to distinguish these two types of disease, we compared their clinical characteristics in this study. Methods: This study retrospectively reviewed 14 OL and 14 OC-BLN patients from Fudan University Shanghai Cancer Center and Shanghai Eighth People's Hospital. The clinical char-acteristics, image and laboratory examination data were compared. Results: There was no significant difference in age, symptom, fever, weight loss and volume of ascitic fluid between the two groups. Comparing with OC-BLN, OL patients have larger tumor in ovaries [(13.04±5.94) cm vs (7.78±6.38) cm, P=0.033], and higher percentage of solid ovarian tumor (85.71% vs 28.5%, P=0.006). Lactate dehydrogenase(LDH)/CA125 was higher in OL (7.66±8.03) than OC-BLN (0.31±0.27, P=0.009). Using LDH/CA125 to diagnose OL, area under the curve (AUC) was 0.952. When the threshold value was set at 1, the sensitivity and specificity was 91.7% and 100%, respectively. Conclusion: OL and OC-BLN are easily to be misdiagnosed. OL has larger and more solid tumor than OC-BLN. LDH/CA125 can help to distinguish these two diseases and guide clinical decision making.
7.Research progress of molecular imaging technology in the diagnosis and treatment of epilepsy
Xinyu WANG ; Mujie GUO ; Qiong NIE ; Qingxia KONG
Chinese Journal of Behavioral Medicine and Brain Science 2022;31(5):474-479
Molecular imaging is a developing research field and it has become a research hotspot.It integrates molecular biochemistry, data processing, nanotechnology, image processing and other technologies and has high specificity, high sensitivity, and high image resolution.It can provide qualitative, positioning, and quantitative data for clinical diagnosis.Clinically, 30% of epileptic patients develop into intractable epilepsy, but magnetic resonance imaging(MRI) can not detect structural lesions.These patients need accurate positioning in order to improve the effectiveness of epilepsy surgery.Because the current preoperative positioning methods have certain limitations, some epileptic patients still have recurrent seizures after the operation.Therefore, researchers continue to explore targeted tracers with high specificity and strong sensitivity.Various nanotechnology and functional magnetic resonance imaging methods are used to study the accurate localization methods of epilepsy.This paper summarized and analyzed the latest research of molecular imaging technology in China and abroad, such as the latest research of single photon emission computed tomography(SPECT) and positron emission tomography(PET) molecular imaging, the application of various nanotechnology combined with functional magnetic resonance in the accurate diagnosis and treatment of epilepsy, and various targeted tracers that haven been developed at present.The results suggest that the continuous improvement of quantitative image analysis, the integration of multi-mode imaging, the development of PET radioactive tracers, and the combination of nanotechnology and functional magnetic resonance imaging(fMRI) will facilitate a more comprehensive understanding of the pathophysiological mechanism of epilepsy.It is promising to realize the accurate diagnosis and treatment of intractable epilepsy.