1.Translation And Validation Of The Malay Post Traumatic Stress Disorder Checklist For Civilians
Rafidah Bahari ; Muhammad N Mohamad Alwi ; Muhammad R Ahmad ; Ismail Mohd Saiboon
ASEAN Journal of Psychiatry 2015;16(2):1-9
Objectives: There are a number of validated questionnaires available for the
screening of Post-Traumatic Stress Disorder (PTSD), and the PTSD Checklist
for Civilians is one of them. However, none was translated into the Malay
Language and validated for use in the Malaysian population. The aim of this
study is to translate and validate the Malay PTSD Checklist for Civilians
(MPCL-C). Methods: The PCL-C was translated into the Malay Language and
back-translated. The reliability and validity of the MPCL-C were then
determined by administering them to those who presented at the emergency
department for motor vehicle accident at least one month before. Results: The
MPCL-C has good face and content validity. In terms of reliability, it is also
good, with Chronbach’s alpha values of 0.90, 0.77, 0.75 and 0.74 for the full
scale, re-experiencing, avoidance and arousal domains respectively. Conclusions:
The MPCL-C is a valid and reliable instrument to screen for PTSD in motor
vehicle accident victims for the studied population.
2.Current status of parasitic infections among Pangkor Island community in Peninsular Malaysia
Ahmad, A.F. ; Ngui, R. ; Muhammad Aidil ; R., Lim, Y.A.L. ; Rohela, M.
Tropical Biomedicine 2014;31(4):836-843
Limited data is available on the prevalence of parasitic infections among the
island communities in Malaysia with most studies performed between 1960s-1980s. This
study was conducted to determine the current prevalence status of parasitic infections
among communities living in Pangkor Island Peninsular Malaysia. A total of 131 stool and 298
serum samples were collected and subjected to microscopic examination for intestinal protozoa
and helminths and detection of Toxoplasma gondii antibodies using commercial ELISA kits
respectively. In addition, thin and thick peripheral blood films were microscopically screened
for the presence of Plasmodium spp. and microfilariae respectively. The overall prevalence
of intestinal parasitic infections among Pangkor Island community was 9.9% (13/131) with T.
trichiura (5.3%) being the most common intestinal parasite detected. Toxoplasmosis was
reported in almost 60% of the community with the seroprevalence being significantly high
among females (64.7%) compared to males (52.8%) (p=0.038). None of those examined samples
were infected with intestinal sarcocystosis, malaria and filariasis. This study revealed that
the prevalence of intestinal parasitic infections among Pangkor Island community has been
greatly reduced compared to that reported 35 years ago. Massive improvements in the
socioeconomic status, personal hygiene, water facilities and sanitation may have contributed
to the low prevalence of parasitic infections in this community. Nevertheless, further studies
still need to be performed to determine the possible risk factors for the high prevalence of
toxoplasmosis in this community.
3.Chronic progressive external ophthalmoplegia in a Saudi patient with a mutation in the POLG gene successfully managed with bilateral frontalis sling
Hussein ALGAHTANI ; Bader SHIRAH ; Khalid ALSAGGAF ; Mohammad H. AL-QAHTANI ; Angham Abdulrahman ABDULKAREEM ; Muhammad Imran NASEER ; Ahmad R. ABUZINADAH
Journal of Genetic Medicine 2021;18(2):121-126
Chronic progressive external ophthalmoplegia (CPEO) is a complex slowly progressive mitochondrial disorder characterized by extraocular muscle weakness with or without multisystem involvement. The mainstay of therapy in a patient with CPEO is supportive. However, in moderate cases, surgery might be indicated including surgeries for ptosis and strabismus. In this article, we report a Saudi patient with CPEO due to compound heterozygous variants in the DNA polymerase gamma (POLG) gene c.2246T>C p.(Phe749Ser) and c.1735C>T p.(Arg579Trp), which are classified as pathogenic. Proper diagnosis with genetic testing confirmation is important to guide the management and counsel the patient about the prognosis and the management options. The patient was successfully managed with bilateral frontalis sling and illustrates the importance of surgical intervention to improve vision and cosmetic appearance in patients with CPEO. We emphasize the importance of multidisciplinary care in the management of cases of mitochondriopathy, especially CPEO.