1.Serum Ferritin Levels: A Potential Biomarker to Represent Child-Turcotte-Pugh Score among Decompensated Liver Cirrhosis Patients
Taufik Sungkar ; Muhammad Fakhrur Rozi ; Leo Basa Dairi ; Lukman Hakim Zain
Malaysian Journal of Medical Sciences 2019;26(2):59-65
Background: Liver cirrhosis and the child-Turcotte-Pugh (CTP) score are inseparable
entities in liver disease. CTP score is largely known as the mortality and prognosis predictor.
Nevertheless, ferritin emerges as a simple biomarker related to prognosis. The study aimed to
determine whether there was a significant correlation between serum ferritin levels and CTP score.
Methods: The study analysed 54 decompensated liver cirrhotic patients including
17 females and 37 males between May 2016 and May 2017 at the Haji Adam Malik General Hospital,
Medan, Indonesia. Ferritin levels were, then, divided into trichotomous cut-off value (< 200 ng/
mL, n = 22; 200–400 ng/mL, n = 5; and > 400 ng/mL, n = 27). Data was analysed using SPSS
version 12.0 (continuous variables were assessed by the Kruskal-Wallis test and Chi-square test
was used for categorical variables). In addition, Spearman correlation test was used to determine
any significant correlation between ferritin levels and CTP score.
Results: Based on data analysis, gender and CTP score were related to higher ferritin
levels (P = 0.002 and P = 0.018, respectively). Furthermore, a significant correlation between
serum ferritin levels and CTP score was obtained in to moderate degree (P = 0.000; r = 0.487).
Conclusions: There might be a significant role of serum ferritin levels in predicting
mortality and prognosis among decompensated liver cirrhosis patients but it still needs further
attention.
2.Ludwig’s Angina in A Rural Hospital- An Infection Spreads from Dental Caries
Adrian Kadafi Lubis ; Muhammad Fakhrur Rozi
Malaysian Journal of Medicine and Health Sciences 2020;16(No.4):384-387
Ludwig's angina is one of the emergency cases associated with impending upper airway obstruction. Through this
case report, the neglected case of emergency medical diagnosis could be prevented and it will become a piece of
evidence for the great importance of collaboration among clinicians. A 17-year old boy admitted to the emergency
setting of a rural public hospital, East Belitung, Indonesia with major complaints of progressively swallowing difficulty
and breathlessness with fever and chills for two weeks before hospital admission. There was a history of dental caries
in mandibular right second molar. Non-surgical and surgical management has been conducted immediately and the
patient was discharged after day three postoperatively. In this rural hospital setting, early and proper management
based on accurate diagnosis is a pivotal step to prevent medical negligence amid limited resources and equipment.