Myxoid liposarcoma is the major subtype of liposarcoma and commonly presents in the
extremities, particularly in the thigh. We introduce an unusual case of a myxoid liposarcoma
presenting as a large perineal swelling occupying the para-rectal and para-anal spaces in a 49-yearold
male patient. The diagnosis, management, and prognosis of myxoid liposarcoma are discussed.
A literature review is performed for myxoid liposarcoma.
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