1.Effective Atomic Number based on Energy Dispersive X-Ray (EDX) Analysis and Carbon Hydrogen Nitrogen (CHN) Analysis for Phantom Material in Medical Physics Applications
Siti Hajar Zuber ; Nurul Ab. Aziz Hashikin ; Mohd Fahmi Mohd Yusof ; Rokiah Hashim ; Mohd Zahri Abdul Aziz
Malaysian Journal of Medicine and Health Sciences 2021;17(No.4):116-121
Introduction: In medical physics applications, effective atomic numbers are often employed to set apart and specify
the interaction of ionizing radiation with matter. Methods: The effective atomic number of soy-lignin bonded with
Rhizophora spp. particleboards were analyzed using Energy Dispersive X-ray analysis and Carbon Hydrogen Nitrogen
Analyzer. The effective atomic number were compared and recorded with reference to the effective atomic value
of water. Results: The result showed that the effective atomic number calculated for adhesive bound Rhizophora spp.
samples were close to effective atomic value of water, with 3.34 – 3.47 % differences by using Energy Dispersive
X-ray and 6.47 – 6.78 % differences by using Carbon Hydrogen Nitrogen analysis. The result revealed that through
Energy Dispersive X-ray method, the effective atomic number was much closer to water compared to Carbon Hydrogen
Nitrogen analysis. Conclusion: Despite the availability of hydrogen content in the samples in Carbon Hydrogen
Nitrogen analysis, Energy Dispersive X-ray method was much more preferred and gave better result compared to
Carbon Hydrogen Nitrogen analysis thus provide a compelling argument for the use of Energy Dispersive X-ray
method to measure the effective atomic number of Rhizophora spp. particleboard in medical physics applications.
2.Proton Therapy: Malaysian Perspective
Ying Chee Keat ; Mohd Hafiz bin Mohd Zin ; Mohd Zahri bin Mohd Abdul Aziz
Malaysian Journal of Medicine and Health Sciences 2020;16(No.4):344-352
Proton therapy is an advanced type of radiotherapy and the use of charged particle proton instead of high energy
X-rays to treat cancer has been increasing in recent years, as it offers superior dose distribution and more effectively
spares healthy tissues compared to conventional radiotherapy. Proton therapy has potential clinical advantages for
some types of tumours that are difficult to treat by conventional radiotherapy, it also has the added benefits of no
exit dose beyond tumour. Many countries that established cancer treatment facilities in the last decade chose proton
therapy because of its lower capital cost and higher cost-effectiveness compared to carbon ions therapy. This review
first describes the physical characteristics of proton beam for radiotherapy, followed by potential clinical benefits of
proton beam therapy in Malaysia. The paper also discusses the challenges of implementing the first proton centre in
Malaysia.
3.Laplace-Based Interpolation Method in Reduction of Metal Artifact in Computed Tomography Imaging
Noor Diyana Osman ; Nurul Fathin Mohamad Sobri ; Anusha Achuthan ; Mohd Norsyafi Hassan ; Muhamad Zabidi Ahmad ; Mohd Zahri Abdul Aziz
Malaysian Journal of Medicine and Health Sciences 2022;18(No.6):243-250
Introduction: Metal artifacts can degrade the image quality of computed tomography (CT) images which lead to errors in diagnosis. This study aims to evaluate the performance of Laplace interpolation (LI) method for metal artifacts
reduction (MAR) in CT images in comparison with cubic spline (CS) interpolation. Methods: In this study, the proposed MAR algorithm was developed using MATLAB platform. Firstly, the virtual sinogram was acquired from CT image using Radon transform function. Then, dual-adaptive thresholding detected and segmented the metal part within
the CT sinogram. Performance of the two interpolation methods to replace the missing part of segmented sinogram
were evaluated. The interpolated sinogram was reconstructed, prior to image fusion to obtain the final corrected
image. The qualitative and quantitative evaluations were performed on the corrected CT images (both phantom and
clinical images) to evaluate the effectiveness of the proposed MAR technique. Results: From the findings, LI method
had successfully replaced the missing data on both simple and complex thresholded sinogram as compared to CS
method (p-value = 0.17). The artifact index was significantly reduced by LI method (p-value = 0.02). For qualitative
analysis, the mean scores by radiologists for LI-corrected images were higher than original image and CS-corrected
images. Conclusion: In conclusion, LI method for MAR produced better results as compared to CS interpolation
method, as it worked more effective by successfully interpolated all the missing data within sinogram in most of the
CT images.