1.Risk factors and outcomes of imipenem-resistant Acinetobacter bloodstream infection in North-eastern Malaysia
Deris Zainy Zakuan ; Shafei Nazri Mohd ; Harun Azian
Asian Pacific Journal of Tropical Biomedicine 2011;(4):313-315
Objective: To determine the risk factors and outcomes of imipenem-resistant Acinetobacterbaumannii (IRAB) bloodstream infection (BSI) cases, since there is very little publication on Acinetobacter baumannii infections from Malaysia. Methods: A cross sectional study of 41 cases (73.2%) of imipenem-sensitive Acinetobacter baumanii (ISAB) and 15 cases (26.8%) of IRAB was conducted in a teaching hospital which was located at North-Eastern state of Malaysia. Results:There was no independent risk factor for IRAB BSI identified but IRAB BSI was significantly associated with longer bacteraemic days [OR 1.23 (95% CI 1.01, 1.50)]. Although prior use of carbepenems and cephalosporin were higher among IRAB than ISAB group, statistically they were not significant. There was no significant difference in term of outcomes between the two groups. Conclusions: Although statistically not significant, this analysis compliments previous publication highlighting the importance of appropriate empiric antibiotic usage in hospital especially carbepenems and need further evaluation with bigger subjects.
2.Risk factors and outcomes of imipenem-resistant Acinetobacter bloodstream infection in North-Eastern Malaysia.
Zakuan Zainy DERIS ; Mohd Nazri SHAFEI ; Azian HARUN
Asian Pacific Journal of Tropical Biomedicine 2011;1(4):313-315
OBJECTIVETo determine the risk factors and outcomes of imipenem-resistant Acinetobacter baumannii (IRAB) bloodstream infection (BSI) cases, since there is very little publication on Acinetobacter baumannii infections from Malaysia.
METHODSA cross sectional study of 41 cases (73.2%) of imipenem-sensitive Acinetobacter baumanii (ISAB) and 15 cases (26.8%) of IRAB was conducted in a teaching hospital which was located at North-Eastern state of Malaysia.
RESULTSThere was no independent risk factor for IRAB BSI identified but IRAB BSI was significantly associated with longer bacteraemic days [OR 1.23 (95% CI 1.01, 1.50)]. Although prior use of carbepenems and cephalosporin were higher among IRAB than ISAB group, statistically they were not significant. There was no significant difference in term of outcomes between the two groups.
CONCLUSIONSAlthough statistically not significant, this analysis compliments previous publication highlighting the importance of appropriate empiric antibiotic usage in hospital especially carbepenems and need further evaluation with bigger subjects.
Acinetobacter Infections ; drug therapy ; epidemiology ; microbiology ; Acinetobacter baumannii ; drug effects ; isolation & purification ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents ; pharmacology ; therapeutic use ; Bacteremia ; drug therapy ; epidemiology ; microbiology ; Case-Control Studies ; Cross-Sectional Studies ; Female ; Hospitals, Teaching ; Humans ; Imipenem ; pharmacology ; therapeutic use ; Malaysia ; epidemiology ; Male ; Middle Aged ; Risk Factors ; Treatment Outcome ; Young Adult ; beta-Lactam Resistance
3.The Proportion of Non-retention and Its Associated Factors Among Clients Receiving Methadone Maintenance Therapy in Kelantan, Malaysia
Mohd Hazwan Baharuddin ; Mohd Azhar Mohd Yasin ; Mohd Nazri Shafei
Malaysian Journal of Medicine and Health Sciences 2021;17(No.2):11-17
Introduction: Methadone maintenance therapy (MMT) requires a client to take a daily dose of methadone to reduce
cravings for opioid and suppress withdrawal syndrome. Non-retention in the MMT will seriously expose more risk
rather than the benefits of the program. Hence, determining the factors associated with non-retention to the MMT
is essential. Thus, the present study was conducted to determine the proportion of non-retention and its associated
factors among clients receiving MMT in Kelantan, Malaysia. Methods: By using a retrospective record review analysis, the required information of the clients was obtained from fourteen MMT clinics in Kelantan, Malaysia. A total
of 155 clients were selected in this study using systematic random sampling. Multiple logistic regression analysis
was performed to determine the factors associated with non-retention among clients receiving MMT. Results: It was
found that the proportion of non-retention to the MMT in Kelantan, Malaysia was 21.9%. Clients with advanced age,
taking daily direct observed therapy, and no underlying HIV were the predictors of non-retention among clients receiving MMT in Kelantan, Malaysia. Conclusion: The findings highlight a relatively high proportion of non-retention
among the MMT clients. There is a need for an integrated, culturally relevant approach towards tackling the factors
associated with non-retention in the future to keep this program sustainable and effective.
4.Co-Curricular Activities and Motives for Participating in Physical Activity among Health Sciences Students at Universiti Sains Malaysia, Malaysia
Garry Kuan ; Nurzulaikha Abdullah ; Yee Cheng Kueh ; Mohd Ismail ; Mohd Nazri Shafei ; Tony Morris
Malaysian Journal of Medical Sciences 2019;26(1):138-146
Background: The purpose of the study was to compare the motives for participating
in physical activity (PA) through the different types of co-curricular activities chosen by health
sciences undergraduate students at Universiti Sains Malaysia (USM), Malaysia.
Methods: The participants were university students at USM’s Health Campus, who were
invited to volunteer and complete two measures: a demographic form, including the types of
co-curricular activities in which the students chose to enrol (sports, uniform and art), and the
Physical Activity and Leisure Motivation Scale (PALMS).
Results: A total of 588 university students (female = 79.1%, male = 20.9%) with a mean
age of 19.77 (SD = 1.39) participated in the study. The results showed significant differences in the
motives of affiliation (P < 0.001), appearance (P = 0.008) and physical condition (P = 0.010) across
the types of co-curricular activities in which the students participated. The students who enrolled
in sports generally showed higher motives of affiliation, appearance and physical condition for
participating in PA than other types of co-curricular activities.
Conclusion: The study findings can provide further insights into the motives for
participating in PA among health sciences students and encouragement for students to integrate
PA into their daily routines.