1.Clinical Factors affecting Minor Amputation in Diabetic Foot Disease at Tengku Ampuan Afzan Hospital, Kuantan
Zamzuri Zakaria ; Mustaqim Aafifi ; Mohd Ariff Sharifudin
Malaysian Journal of Medical Sciences 2015;22(2):41-47
Background: Diabetic foot disease poses a substantial problem in Malaysian diabetic population. We evaluate the clinical factors affecting minor amputation in diabetic foot disease.
Methods: A cross-sectional study enrolling patients admitted to orthopaedic wards of a single tertiary hospital for diabetic foot disease was conducted. Patients who had undergone major amputation or with medical condition above the ankle joint were not included. Clinical data were collected by measurement of ankle brachial systolic index and Semmes-Weinstein 5.07 gauge monofilament test with foot clinical evaluation using King’s classification respectively.
Results: The total number of patients included was 138, with mean age of 59.7 years (range 29 to 94 years old). Fifty patients (36.2%) had minor amputations. Poor compliance to diabetic treatment, King’s classification stage 5, low measures of ankle brachial systolic index, sensory neuropathy, high serum C-Reactive protein and high serum creatinine are significant predictive factors for minor amputation (P < 0.05).
Conclusion: Identifying these risk factors may help in prevention of minor amputation and subsequently reduce limb loss in diabetic foot.
2.Chronic Tibial Osteomyelitis in Children. A Case Review at Hospital Tengku Ampuan Afzan, Kuantan
Mohd Shukrimi Awang ; Mohd Ariff Sharifudin ; Zamzuri Zakaria ; Mai Nurul Ashikin Taib
The Medical Journal of Malaysia 2015;70(1):48-51
Osteomyelitis in children has various clinical manifestations
causing diagnostic and therapeutic difficulties.
Inappropriate treatment of acute osteomyelitis may lead to
chronic, serious and complicated condition. Chronic
osteomyelitis continues to be a major cause of morbidity
and disability in children living in developing countries. We
present three cases of tibial osteomyelitis that have different
presentations and sequalae. Our intention is to alert our
colleagues, particularly primary physicians, regarding the
variety of presentation and the important of early diagnosis
and treatment to reduce the risk of morbidity following
osteomyelitis.
Osteomyelitis
3.A Rare Case of Monostotic Spinal Fibrous Dysplasia Mimicking Solitary Metastatic Lesion of Thyroid Carcinoma
Mohd Ariff Sharifudin ; Zamzuri Zakaria ; Mohamed Saufi Awang ; Mohamed Azril Mohamed Amin ; Azian Abd Aziz
Malaysian Journal of Medical Sciences 2016;23(1):82-86
Monostotic fibrous dysplasia of the vertebra is a rare entity. A case of a 53-year-old lady who presented with an 8 months history of pain in the thoracic spine region with paraparesis is discussed. She had a history of papillary thyroid carcinoma and had undergone total thyroidectomy one year prior to her current problem. Magnetic resonance imaging revealed isolated osteolytic lesion over the posterior element of the T12 vertebra with narrowing of the spinal canal causing compression of the cord. The diagnosis of fibrous dysplasia was made histologically. Fibrous dysplasia rarely occurs in axial bones compared with peripheral bones. This case illustrates that osteolytic lesion of the vertebrae should be evaluated with detailed radiological and histopathological examination before an empirical diagnosis of spinal metastasis is made in an adult with a background history of primary malignancy well-known to spread to the bone.
Fibrous Dysplasia, Monostotic
4.Preoperative physiotherapy and short-term functional outcomes of primary total knee arthroplasty.
; Mohd Ariff SHARIFUDIN ; Amran Ahmed SHOKRI ; Shaifuzain Ab RAHMAN
Singapore medical journal 2016;57(3):138-143
INTRODUCTIONPhysiotherapy is an important part of rehabilitation following arthroplasty, but the impact of preoperative physiotherapy on functional outcomes is still being studied. This randomised controlled trial evaluated the effect of preoperative physiotherapy on the short-term functional outcomes of primary total knee arthroplasty (TKA).
METHODS50 patients with primary knee osteoarthritis who underwent unilateral primary TKA were randomised into two groups: the physiotherapy group (n = 24), whose patients performed physical exercises for six weeks immediately prior to surgery, and the nonphysiotherapy group (n = 26). All patients went through a similar physiotherapy regime in the postoperative rehabilitation period. Functional outcome assessment using the algofunctional Knee Injury and Osteoarthritis Outcome Score (KOOS) scale and range of motion (ROM) evaluation was performed preoperatively, and postoperatively at six weeks and three months.
RESULTSBoth groups showed a significant difference in all algofunctional KOOS subscales (p < 0.001). The mean score difference at six weeks and three months was not significant in the sports and recreational activities subscale for both groups (p > 0.05). Significant differences were observed in the time-versus-treatment analysis between groups for the symptoms (p = 0.003) and activities of daily living (p = 0.025) subscales. No significant difference in ROM was found when comparing preoperative measurements and those at three months following surgery, as well as in time-versus-treatment analysis (p = 0.928).
CONCLUSIONSix-week preoperative physiotherapy showed no significant impact on short-term functional outcomes (KOOS subscales) and ROM of the knee following primary TKA.
Activities of Daily Living ; Arthroplasty, Replacement, Knee ; Female ; Follow-Up Studies ; Humans ; Knee Joint ; physiopathology ; Male ; Middle Aged ; Osteoarthritis, Knee ; physiopathology ; therapy ; Physical Therapy Modalities ; Preoperative Care ; methods ; Range of Motion, Articular ; physiology ; Recovery of Function ; Retrospective Studies ; Time Factors ; Treatment Outcome
5.Relationship between pulmonary function and degree of spinal deformity, location of apical vertebrae and age among adolescent idiopathic scoliosis patients.
Joehaimey JOHARI ; Mohd Ariff SHARIFUDIN ; Azriani Ab RAHMAN ; Ahmad Sabri OMAR ; Ahmad Tajudin ABDULLAH ; Sobri NOR ; Weii Cheak LAM ; Mohd Imran YUSOF
Singapore medical journal 2016;57(1):33-38
INTRODUCTIONThis retrospective review aimed to examine the relationship between preoperative pulmonary function and the Cobb angle, location of apical vertebrae and age in adolescent idiopathic scoliosis (AIS). To our knowledge, there have been no detailed analyses of preoperative pulmonary function in relation to these three factors in AIS.
METHODSA total of 38 patients with thoracic or thoracolumbar scoliosis were included. Curvature of spinal deformity was measured using the Cobb method. Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were used to evaluate preoperative pulmonary function. Statistical methods were used to analyse the relationship between preoperative pulmonary function and the factors that may contribute to poor pulmonary function.
RESULTSThe mean age of the patients was 16.68 ± 6.04 years. An inverse relationship was found between the degree of the Cobb angle and FVC as well as FEV1; however, the relationships were not statistically significant (p = 0.057 and p = 0.072, respectively). There was also a trend towards a significant negative correlation between the thoracic curve and FVC (p = 0.014). Patients with larger thoracic curves had lower pulmonary function. A one-year increase in age significantly decreased FVC by 1.092 units (p = 0.044). No significant relationship between age and preoperative FEV1 was found. The median FVC was significantly higher in patients with affected apical vertebrae located at levels L1-L3 than at T6-T8 or T9-T12 (p = 0.006).
CONCLUSIONLung function impairment was seen in more severe spinal deformities, proximally-located curvature and older patients.
Adolescent ; Adult ; Female ; Follow-Up Studies ; Forced Expiratory Volume ; physiology ; Humans ; Kyphosis ; diagnosis ; physiopathology ; surgery ; Lumbar Vertebrae ; Lung ; physiopathology ; Male ; Preoperative Period ; Respiratory Function Tests ; Retrospective Studies ; Scoliosis ; diagnosis ; physiopathology ; surgery ; Severity of Illness Index ; Spinal Fusion ; methods ; Thoracic Vertebrae ; Young Adult