[Objective]To analyse the content of secondary metabolisms and antibacterial activity of Monochasma Savatieri Franch.ex Maxim.[Method]The contents of 5 secondary metabolites such as flavonoid,chlorogenic acid,tannin,phenol and anthraquinones in the different extracts of Monochasma savatieri Franch.ex Maxim were determined.[Results]It showed that the antibacterial activity of the liquids extracted with 70% ethanol,60% acetone on Streptococcus pneuoncae,Staphylococcus aureus,Escherichia coli and Bacillus subtilis were moderate,while that of the liquids extracted with water was weak.The liquids extracted with 70 ethanol were the better inhibitor of Streptococcus pneuoncae and Staphylococcus aureus,while the liquids extracted with 60 acetone were the better inhibitor of Escherichia coli and Bacillus subtilis.[Conclusion]There was positive correlation between the antibacterial activity of the liquids of Monochasma savatieri Franch.ex Maxim on Escherichia coli and the content of the chologenic acid.There was also marked correlation between that of Baillus subtilis and anthra quinones.