1.Optimization of mandibular CT scanning
Liyu ZHOU ; Minxia JIANG ; Haiying RAO
Chinese Journal of Radiological Medicine and Protection 2014;34(11):870-871,880
Objective To Optimize the mandibular CT scanning methods with changing the scanning position,to reduce the radiation dosage.Methods Totally 50 consecutive patients with mandibular CT examination were enrolled in the study and divided into position-optimized group and routine group (n =25,respectively) randomly.The image quality,volume CT-dose index (CTDIvol),scanning length,and dose length product (DLP) were compared.Results There was no significant difference in subjective image quality and CTDIvol between two groups.But the scanning length and DLP in positionoptimized group were significantly reduced by about 20 % (t =4.986,P < 0.05) and 16% (t =3.682,P <0.05) compared with routine group.The lens were out of scanning field with the position-optimized protocol.Conclusions The scanning length would be efficiently reduced and the lens avoided with the position-optimized protocol,which would subsequently reduce the effective radiation dose.
2.Qualitative research on the factors affecting long-term compliance to weight management of patients with congestive heart failure
Yang JU ; Qi WANG ; Jingbo QIU ; Xiaohua WANG ; Qing JIANG ; Minxia LU ; Xiaofang YANG
Chinese Journal of Practical Nursing 2013;29(35):52-55
Objective To explore factors affecting long-term compliance to weight management (WM) of patients with congestive heart failure (CHF)and to provide evidence for improving patients' compliance.Methods In-depth semi-structured interviews based on reinforcement theory were conducted among 18 CHF patients who received WM intervention over 6 months.The data were analyzed by Colaizzi analysis program.Results Three themes were found:precipitating factors such as the correct perception of disease and self-efficacy,the factors of positive reinforcement such as early gains from WM,readmission,follow-up,family and social support,as well as the factors of negative reinforcement such as gaining nothing during long period,physical and mental disorders.These above factors made long-term compliance to WM of 50% of the participants dynamic and fluctuant.Conclusions Medical staff should identify patients'compliance at different stages in time during follow-up,analyze the factors that affect their compliance,and then grasp the optimal timing of intervention to perform targeted,multiform and multiple health education to improve compliance.
3.The influencing factors for the infection occurring after TACE in patients with liver cancer
Minxia JIANG ; Xugao CHEN ; Hongxiang YAO
Journal of Interventional Radiology 2018;27(2):133-136
Objective To investigate the incidence and influencing factors of postoperative infection in patients with hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE). Methods A retrospective study was conducted on the HCC patients who received TACE during the period from January 2016 to December 2016. The possible risk factors that might induce postoperative infection after TACE were evaluated by using univariate analysis and multivariate logistic regression analysis. The risk factors were further stratified into very high risk factors, high risk factors, moderate risk factors and low risk factors. Results Among 386 HCC patients who showed effective response to TACE, postoperative infection occurred in 17 patients, the incidence rate was 4.4%. Ascites, history of hepatobiliary resection surgery or preoperative liver cancer rupture with bleeding, history of liver abscess or previous postoperative infection after TACE were the very high risk factors of infection after TACE. Preoperative serum total protein value <60 g/L was a high risk factor. The presence of tumor thrombus in portal vein or in vena cava was a moderate risk factor. Conclusion Ascites, previous hepatobiliary surgery, preoperative liver cancer rupture with bleeding, history of liver abscess and history of infection after TACE are significantly correlated with the occurrence of infection after TACE.
4.Protocol of automatically processing 2 U frozen red blood cells
Yan WANG ; Minxia LIU ; Hai CHENG ; Wenjing LI ; Jiexi WANG ; Wei DU ; Ying HAN ; Donggen WANG ; Xuebing JIANG
Military Medical Sciences 2015;(2):136-139
Objective To improve the processing protocol of the frozen erythrocyte ( RBC) washing machine of the dialysis type to enhance its efficiency of treating the 2 U frozen RBCs .Methods The frozen RBC washing machine for dialysis was used to deglycerolize the 2 U frozen RBCs after thawing .Measures including adjustment of the Pump speed , washing buffer adding and solution osmolarity were taken to decrease the processing time .Hemoglobin(Hb) content, Hb recovery, residual glycerol, free Hb content, deforming ability, and apoptosis of the deglycerolized RBCs were assessed to evaluate the efficiency of the improved protocol .Results As for the cells processed respectively by the previous and improved protocols, contents of Hb were (35.03 ±4.20) g and (53.82 ±2.08) g, respectively; Hb recoveries were (61.10 ±8.46)% and (80.22 ±3.73)%,respectively.Osmolarities representing residual glycerol were (307.00 ± 14.50)mOsm and (322.00 ±29.00)mOsm.Free Hb values were (0.74 ±0.04) and (0.80 ±0.08)g/L.The processing time was (1.64 ±0.31) and (1.04 ±0.16) h,respectively.There were significant differences in Hb content , Hb recovery, and deforming ability between the cells processed by the two protocols respectively .However , there were no significant changes in glycerol contents , free Hb, and apoptosis extent between the cells processed by the two protocols .Conclusion The innovated protocol can improve the quality of washed frozen RBCs , decrease the processing time and enhance the efficiency of the machine.
5.Development and validation of a prognostic nomogram model for patients with the lower third and abdominal oesophageal adenocarcinoma
Zhengshui XU ; Dandan LIU ; Jiantao JIANG ; Ranran KONG ; Jianzhong LI ; Yuefeng MA ; Zhenchuan MA ; Jia CHEN ; Minxia ZHU ; Shaomin LI
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2025;32(02):201-207
Objective To establish an individualized nomogram model and evaluate its efficacy to provide a possible evaluation basis for the prognosis of lower third and abdominal part of oesophageal adenocarcinoma (EAC). Methods Lower third and abdominal part of EAC patients from 2010 to 2015 were chosen from the SEER Research Plus Database (17 Regs, 2022nov sub). The patients were randomly allocated to the training cohort and the internal validation cohort with a ratio of 7∶3 using bootstrap resampling. The Cox proportional hazards regression analysis was used to determine significant contributors to overall survival (OS) in EAC patients, which would be elected to construct the nomogram prediction model. C-index, calibration curve and receiver operating characteristic (ROC) curve were performed to evaluate its efficacy. Finally, the efficacy to evaluate the OS of EAC patients was compared between the nomogram prediction model and TNM staging system. Results In total, 3945 patients with lower third and abdominal part of EAC were enrolled, including 3475 males and 470 females with a median age of 65 (57-72) years. The 2761 patients were allocated to the training cohort and the remaining 1184 patients to the internal validation cohort. In the training and the internal validation cohorts, the C-index of the nomogram model was 0.705 and 0.713, respectively. Meanwhile, the calibration curve also suggested that the nomogram model had a strong capability of predicting 1-, 3-, and 5-year OS rates of EAC patients. The nomogram also had a higher efficacy than the TNM staging system in predicting 1-, 3-, and 5-year OS rates of EAC patients. Conclusion This nomogram prediction model has a high efficiency for predicting OS in the patients with lower third and abdominal part of EAC, which is higher than that of the current TNM staging system.