1.Therapeutic review of 23 subependymal giant-cell astrocytoma
Lijiang HAN ; Jizong ZHAO ; Zhenyu MA ; Song LIN ; Yuanli ZHAO ; Ge YUAN ; Nan JI ; Yongji TIAN ; Tong REN ; Dong ZHANG ; Zhenrong SUN ; Xinru XIAO ; Kai TANG ; Mingxue PIAO ; Xueji LI ; Hai LIU ; Xun YE ; Xiaolin CHEN
Chinese Journal of Postgraduates of Medicine 2009;32(23):18-21
Objective To analyze and estimate, the treatment of patients with histologically confirmed subependymal giant-cell astroeytoma (SEGCA). Methods The data from 23 patients with SEG-CA who were diagnosed between February 1995 and February 2008 were retrospectively evaluated. Various combinations of surgery and radiotherapy had been used for treatment. Results Total resection was 16 cases, subtotal resection was 7 cases, radiotherapy was 17 cases. The average follow-up time was 53 months.One postoperative SEGCA recurrence. Epilepsy was totally disappeared in 17.6% (3/17), partly disappeared in 47.1%(8/17). All cases survived. Conclusions The key of treatment is total resection. The significance of radiotherapy is not sure. The overall prognosis of SEGCA is favorable.
2.Central neurocytoma: analysis of 71 cases
Lijiang HAN ; Jizong ZHAO ; Shuo WANG ; Ge YUAN ; Nan JI ; Yongji TIAN ; Tong REN ; Dong ZHANG ; Zhenrong SUN ; Xinru XIAO ; Kai TANG ; Mingxue PIAO ; Xueji LI ; Hai LIU ; Xun YE ; Xiaolin CHEN
Chinese Journal of Postgraduates of Medicine 2009;32(17):1-4
Objective To examine the diagnosis and outcomes in the treatment of the patients with histologically confirmed central neurocytoma (CNC). Methods The data from 71 patients with CNC who were diagnosed between March 2003 and December 2007 were retrospectively evaluated. Various combinations of surgery, and radiotherapy had been used for treatment. Results The average bulk of tumors was 40 cm3. The median follow-up was 22 months. The 22 months overall survival and local control rate was 95.8%(68/71) and 95.6%(65/68), respectively. Conclusions The overall prognosis is favorable although the follow-up is not very long. Surgery and postoperative radiotherapy can significantly improve local control.