Objective To investigate the family function and features of parental attachment in children with tic disorders ,and to provide evidence for their family intervention. Methods Fifty three children with tic disorders and eighty five normal controls were investigated by family adaptability and cohesion scales, second edition, Chinese version (FACES Ⅱ-CV) and attachment security scale(Kems Security Scale). Results Actual cohesion scores,actual adaptability scores and ideal adaptability scores of the tic disorders children were all lower than those controls((66.87 12.53) vs (72. 14 11. 05) , (44. 19 9.70) vs (49.01 9.19), (52. 38 9. 10) vs (57.10 8.60), P<0.05, P<0.01); the ratio of the Disengaged type of cohesion in the tic disorders children was higher than that of normal controls(25.5% vs 5.9% , P<0.01) ;the ratio of the Rigid type of adaptability was higher than that of normal controls(55.3% vs 25.9% , P<0.01) ;the ratio of the Flexible type of adaptability was lower than that of normal controls( 12.8% vs 30.6% , P<0.05) ;the proportion of the type of extreme in the tic disorders children was higher than that of normal controls(40. 4% vs 23. 5% , P<0. 05). Father-dependence, mother-dependence, mother-intimacy, father-child attachment, mother-child attachment were all lower than those controls. In cases,positive correlation was found not only between actual cohesion scores and father-dependence, mother-dependence, mother-intimacy, father-child attachment, mother-child attachment, but also between actual adaptability scores and the above-mentioned five factors (0.291≤ r≤0.445,0. 301 ≤ r ≤0. 504). Mother-child attachment as an independent variable was separately leaded into the multiple progressively regression model for actual cohesion scores and actual adaptability scores(P<0.01). Conclusion The family function and parental attachment security of the tic disorders children were lower than the controls.

Objective To explore the clinical effect of lateral-rectus approach for treatment of acetabular fracture combined with ipsilateral pelvic fracture. Methods From January 2010 to February 2014, 24 patients with acetabular fracture combined with ipsilateral pelvic fracture were surgically managed through the lateral-rectus approach. Eighteen cases of merely anterior acetabular and pelvic fractures were treated with the lateral-rectus approach only, in the supine position. Six cases involving the posterior acetabular wall and posterior column were treated with the lateral-rectus approach combined lateral-rectus and posterior Kocher-Langenbeck approaches, in the floating position. The titanium reconstruction plates and cannulated screws were applied in these cases. Results The operation time was 70- 185 min and the intraoperative blood loss was 420-1 100 ml. Postoperative X-ray and CT exams showed excellent and good reduction. According to the postoperative Matta radiological evaluation, reduction of acetabular fracture was rated as anatomic in 13 cases, with satisfactory reduction in 8 cases and unsatisfactory in 3 cases. Injury to the sciatic nerve occurred in one case, and fat liquefaction at the abdominal incision in one case. All the patients were followed up for 13-30 months and the fractures healed after 10-16 weeks. According to the modified Merle d'Aubigne and Postel scoring system, 16 cases were excellent, 6 cases were good and 2 cases were fair 6 months after operation. Conclusions Surgical management of acetabular fractures through the lateral-rectus approach can provide adequate exposure and treatment for not only the acetabular fractures involving the anterior column and the quadrilateral surface, but also ipsilateral fractures involving the pubic superior ramus, iliac ala and sacroiliac joint, leading to fine outcomes.

Oncosis is another form of cell death, which is different from apoptosis. The review will discuss the recent advances of oncosis on pathological morphology, nuclear biochemical changes and molecular mechanisms. [

[Objective] To research the plantar pressure distribution of the normal Chinese adult. [Method] The F-scan plantar pressure analysis system was used to collect plantar pressure distribution data of 100 volunteers who stand, walk, jog, go upstairs and downstairs.The plantar pressure distribution data of 5 kinds of physiological states, as well as influence of sex, height, body weight, body mass index and speed was analyzed. [Result] There's different characteristic between 5 kinds of states of the plantar pressure distribution in the Chinese normal adults. There's significant difference between static and dynamic. In four dynamic motions, the gait of walk was stalest, and it became unstable if speed up and go upstairs or downstairs. As for the influential factors of the plantar pressure distribution, there was non-significance of sex. But the speed had the significance. The height, the body weight, the BMI had weak correlation with the plantar pressure distribution. [Conclusion] The plantar pressure distribution of normal Chinese adults has the distinctive quality. The data obtained by this experiment, may provide the reference for the clinical plantar pressure analysis.

Near-infrared technology can be used as an auxiliary means for the early diagnosis of cancer and for surgical resection of tiny lesion that can not be discriminated by naked eyes,but it can not satisfy the purpose when used alone.Thus,we have developed an integrated technique by combining near-infrared and other technologies,and extended the scope of its application.This article reviews the advances of several integrated techniques applied to tumor research,including double labeled technology of nuclide and near-infrared,the combination of near-infrared and fluorescence resonance energy transfer,the combined use of near-infrared and endoscopy,and the integration of near-infrared with carbon nanotubes.

Fluorescence imaging of animal in vivo is to tag cell or DNA with fluorescence reporter gene, and then detect the fluorescence using sensitive optics apparatus. With this system, researcher can observe tumor growth, metastasis and angiogenesis in vivo, and reliable information for tumor diagnosis and treatment will be provided for researcher.

Objective To explore agreement between parent-child report of self-rating scale of systemic family dynamics (SSFD),as well as factors that may influence the agreement.Methods SSFD was used to investigate the agreement between parent and child reports on family dynamics in a sample of 639 Chinese children aged 10 to 18 years from Mainland China,and possible influence factors.Results The results showed that there was significant difference between parent-child report of SSFD.The parents had significant lower score than their children at atmosphere,individuation and disease conception and had higher score at system logic (all P＜0.01).But the two still had significant positive correlation (correlations ranging from 0.15 to 0.38),indicating a low to moderate agreement between them(r=-0.15-0.38,all P＜0.01).The age factor was related to parent-children agreement on SSFD.Parent-child agreement was highest for family atmosphere,followed by individuation,system logic and disease conception.The age factor was related to parent-child agreement on SSFD.Conclusions Both parents' and children's reports of SSFD can be used to assess family dynamics,however,attention should be payed to the affection of parent-child report's difference and age factor to the results.

OBJECTIVE: To investigate the inhibition effects of compound leech eye drops (Co-SZ) on apoptosis of lens epithelial cells (LECs) induced by hydrogen peroxide (H2O2) and the expressions of apoptosis-related genes Bcl-2 and Bax in rats. METHODS: All fresh transparent LECs in SD rats were bathed in culture medium with H2O2 in vitro, meanwhile Co-SZ were added in the culture medium. All LECs were incubated for 24 hours. The apoptosis rate of LECs was determined by terminal deoxynucleotidyl transferase mediated biotin-dUTP nick end labeling method (TUNEL). The changes of LEC ultrastructure and the formation of apoptotic body were observed by transmission electron microscopy. The expressions of apoptosis-related genes Bcl-2 and Bax were detected by streptavdin-peroxidase-biotin method. RESULTS: The apoptosis rate of LECs in the Co-SZ-treated group was significantly lower than that in the H2O2-treated group. The changes of apoptotic LEC ultrastructure in the Co-SZ-treated group were less than those in the H2O2-treated group. The expression of Bcl-2 protein was up-regulated and the expression of Bax protein was down-regulated in the Co-SZ-treated group as compared with the H2O2-treated group. CONCLUSION: The LEC apoptosis induced by H2O2 can be inhibited by Co-SZ. The molecular mechanisms of Co-SZ in inhibiting LEC apoptosis may be related to regulating the expressions of apoptosis-related genes Bcl-2 and Bax.

Objective To study the effect of intra-pulmonary arterial anti-tumor necrosis factor-α antibody(TNF-α Ab) on ultra-structure of lung after cardiopulmonary bypass (CPB).Methods Forty New Zealand rabbits were selected and randomly divided into four groups:group Ⅰ-Ⅲ underwent CPB; group Ⅳ only received open chest operation.In the group Ⅱ,rabbit TNF-α Ab(27 ng/kg) was dropped into the pulmonary artery when the aorta was clamped and CPB continued 30 minute.Pulmonary arterial perfusion was given to the group I instead.Blood TNF-α and neutrophils count from right and left atrium and oxygenation index in the four groups were determined perioperatively.Lung water content,TNF-αmessenger RNA,Bcl-2 protein,Bax protein,Bcl-2/Bax,apoptosis index and pathomorphological change were measured in the lung tissues.Results TNF-α Ab can restrain leukocyte accumulation and reduce releasing of TNF-α in the lung and improve oxygenation index.Moreover,TNF-α Ab can reduce the expression of Bax on alveolar epithelial cells and alleviate the decreasing of the expression of Bcl-2.It can also reduce the occurrence of apoptosis and attenuate pathomorphological changes in the lung tissue.Conclusion Intra-pulmonary arterial antitumor necrosis factor-α antibody markedly lessens the injury of inflammatory reaction and ultra-structure of lung after CPB via Bcl-2/Bax pathway.

Objective: To study the effect of enteral nutrition in the treatment of heart failure with hyponatremia.Methods: Forty patients sufferd from heart failure with hyponatremia were divided into two groups at random: control group(n=20) with regular therapy and treatment group(n=20) with enteral nutrtion on the base of regular therapy.Time intervals from hyponatremia to normal natremia of the two groups were compared.Results: Time interval from hyponatremia to normal in the treatment group was 5.30?1.82 days,and that in the control group was(8.85?2.44) days.Conclusion: The treatment with enteral nutrition can significantly shorten the clinical treatment time in heart failure with hyponatremia.