1.Efficacy of a new microbubble contrast agent of C_3F_8 in opacification of left ventricle
Yinguang SUN ; Mingqiang ZHUANG ; Zhongwei SHI
Chinese Journal of Ultrasonography 2003;0(10):-
Objective To evaluate the efficacy of a new micro-bubble contrast agent of C_3F_8 in the opacification of the left ventricle. Methods Seven pigs received a bolus injection of C_3F_8 (0.002) and (0.02) (ml/kg) intravenously. Left ventricular opacification grades and number of endocardial border delineation segments were observed and left ventricular ejection fraction(LVEF) were measured using modified Simpson method after each intravenous contrast injection. Heart rate and respiration rate were recorded before and after each injection. Results There was a significant improvement for every measurement of contrast enhancement in each intravenous injection. In addition, part of myocardial tissue could be enhanced after contrast injection. There was no difference in heart rate and respiration rate between pre- and post-injection. Conclusions This new contrast agent is safe and helpful in delineating endocardial border of the left ventricle.
2.Significance of certain experiments relevant to airflow parameters in assessment of voice function.
Mingqiang YU ; Han PAN ; Li ZHOU ; Yanchao JIAO ; Juanjuan SUN ; Peiyun ZHUANG ; Email: PEIYUN_ZHUANG@YAHOO.COM.
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2015;50(12):983-988
OBJECTIVETo investigate the role of airflow parameters of some specific examinations in voice function assessment.
METHODSThe s/z ratio, pulmonary function and phonatory aerodynamic parameters were measured in subjects with benign vocal fold lesions and with normal voice. The effect of treatment in subjects with benign vocal fold lesions was evaluated with the phonatory aerodynamic parameters.
RESULTSThe value of s/z ratio in the disease group was higher than that in the normal group (P<0.05). The value of PEF was significantly different between the disease group and the normal group for male (P<0.05). MFR, MPT, PTF, SGP, PTP, VE were significantly different between the disease group and the normal group (P<0.05). MFR, MPT, PTF, SGP, PTP of the disease group after surgery for both sex were significantly different from before surgery (P<0.05). The disease group was subdivided into two groups through stroboscopic examination before and one month after surgery: the worse group (with some functional laryngeal abnormality, or organic abnormality except benign vocal fold lesion) and the better group. PTF, PTP, SGP, VE were significantly different between the worse group and the normal voice group. There was almost no significant difference for aerodynamic parameters between the better group and the normal voice group (P>0.05). There was no significant difference between the worse group after 8 weeks'voice training and the normal voice group (P>0.05).
CONCLUSIONSs/z ratio, aerodynamic parameters (MFR, MPT, SGP, PTF, PTP, VE) are valuable for the diagnosis and assessment of the voice disorders. Aerodynamic parameters are sensitive to the change of glottal function during the treatment. Voice training can increase the glottal function of patients after laryngeal microsurgery.
Female ; Humans ; Larynx ; surgery ; Male ; Microsurgery ; Phonation ; Respiration ; Vocal Cords ; physiopathology ; Voice Disorders ; surgery ; therapy ; Voice Training
3. The impact of male circumcision on the natural history of genital HPV infection: a prospective cohort study
Feixue WEI ; Meng GUO ; Xinjing MA ; Yue HUANG ; Ya ZHENG ; Lin WANG ; Yan SUN ; Sijie ZHUANG ; Kai YIN ; Yingying SU ; Shoujie HUANG ; Mingqiang LI ; Ting WU ; Jun ZHANG
Chinese Journal of Preventive Medicine 2018;52(5):486-492
Objective:
To analyze the correlation between circumcision and incidence and clearance of male genital HPV infection.
Methods:
From May to July 2014, 18-55 year old men who had sexual behavior history were recruited from the general population in Liuzhou, Guangxi to set up a cohort. Totally, 113 circumcised and 560 uncircumcised men were enrolled and interviewed using a questionnaire (including information on demographic characteristics and sexual behaviors), then they were followed-up with 6-month interval for 2 times. On each visit, specimens of male external genitalia were collected and genotyped for HPV DNA. The differences of incidence and clearance of genital HPV infections between circumcised and uncircumcised men were analyzed by Log-rank test. Cox regression was used to analyze the relationship between circumcision and incidence and clearance of HPV infection.
Results:
The median age (