Objective To investigate the value of plasma troponin ,B-type natriuretic peptide and D-dimer in the clinical diagnosis of acute pulmonary embolism .Methods A total of 116 patients with acute pulmonary embolism were randomly selected and divided into high-risk group and low-risk group according to the patient′s condition ,58 patients in each group .Enzyme-linked immunosor-bent assay was used to detected levels of plasma troponin ,B-type natriuretic peptide and D-dimer .Results The plasma troponin and B-type natriuretic peptide levels in the high-risk group were significant higher than those of the low-risk group(P<0 .05) ,but there was no significant difference on D-dimer level(P>0 .05) .The positive rate of plasma troponin(61 .21% )and B-type natriuretic pep-tide(74 .14% )were significant higher than that of D-dimer(36 .21% ) ,the differences were significant(P<0 .05) .The sensitivity of D-dimer was 81 .4 % ,specificity was 86 .7% .The sensitivity of plasma troponin was 95 .6% ,the specificity was 86 .7% .The sensi-tivity of B-type natriuretic peptide was 97 .1% ,the specificity was 95 .9% .The sensitivity and specificity of plasma troponin and B-type natriuretic peptide were significant higher than D-dimer(P<0 .05) .Conclusion Plasma troponin ,B-type natriuretic peptide and D-dimer have certain implications for the clinical diagnosis of acute pulmonary embolism ,but plasma troponin ,B-type natriuretic peptide has better sensitivity and specificity compared with D-dimer .

Objective To explore the effect of bronchoalveolar lavage combined with mechanical ventilation on the clinical symptoms and pulmonary function of elderly patients with severe asthma.Methods A total of 70 patients with severe asthma were selected and randomly divided into observation group and control group.The observation group was given routine treatment,bronchoalveolar lavage and mechanical ventilation,while the control group was given routine treatment and mechanical ventilation.Clinical symptoms,airway function,inflammatory mediators and effect were compared between two groups.Results The effective rate of observation group was 94.29%,which was significantly higher than 77.14% of control group (P<0.05).Clinical symptoms,duration of mechanical ventilation and ICU stay of observation group were significantly shorter than the control group (P<0.05).In the observation group,FEV1,FVC and FEV1/FVC% were significantly higher than the control group (P<0.05),and CRP,TNF-α and IL-6 were significantly lower than the control group (P<0.05).Conclusion Bronchoalveolar lavage combined with mechanical ventilation can improve the clinical symptoms and pulmonary function,alleviate the inflammatory reaction and improve the therapeutic effect.

Objective To explore the effect of bronchoalveolar lavage combined with mechanical ventilation on the clinical symptoms and pulmonary function of elderly patients with severe asthma.Methods A total of 70 patients with severe asthma were selected and randomly divided into observation group and control group.The observation group was given routine treatment,bronchoalveolar lavage and mechanical ventilation,while the control group was given routine treatment and mechanical ventilation.Clinical symptoms,airway function,inflammatory mediators and effect were compared between two groups.Results The effective rate of observation group was 94.29%,which was significantly higher than 77.14% of control group (P<0.05).Clinical symptoms,duration of mechanical ventilation and ICU stay of observation group were significantly shorter than the control group (P<0.05).In the observation group,FEV1,FVC and FEV1/FVC% were significantly higher than the control group (P<0.05),and CRP,TNF-α and IL-6 were significantly lower than the control group (P<0.05).Conclusion Bronchoalveolar lavage combined with mechanical ventilation can improve the clinical symptoms and pulmonary function,alleviate the inflammatory reaction and improve the therapeutic effect.