1.Analysis on the Utilization of Antidepressant Drugs in Our Hospital during2002~2004
China Pharmacy 1991;0(04):-
OBJECTIVE:To evaluate the status quo and the developmental trend of the application of antidepressant drugs in our hospital.METHODS:The antidepressant drugs in our hospital during2002~2004were analyzed retrospectively in terms of drug varieties,consumption quantity,consumption sum,DDDs etc.RESULTS:The consumption sum of the antidepressant drugs increased year by year,which stood at667.41,802.47and995.02(RMB:ten thousand yuan),respectively in the3years.CONCLUSION:Fluoxetine dominates the first place in terms of clinical application of antidepressants.Furthermore,the application of new type antidepresants has been on the rise.
2.Establishment of Efficient Quality Guarantee System for Total Nutrient Admixture
Li LI ; Minglan ZHENG ; Liping YANG
China Pharmacy 2001;0(10):-
OBJECTIVE:To discuss the way to establish a scientific and rational quality guarantee system for total nutrient admixture(TNA).METHODS:The regulations and measures adopted to guarantee TNA quality were analyzed on the basis of TNA preparation practice in the hospital.RESULTS&CONCLUSION:TNA quality can be guaranteed to be secure and stable in quality by establishing an efficient quality guarantee system for TNA.
3.Content Determination of Bifonazole Gel from Different Manufacturers by HPLC
Yanmei QIAN ; Minglan WU ; Jie ZHENG
China Pharmacy 2016;27(15):2117-2118,2119
OBJECTIVE:To evaluate the quality of Bifonazole Gel from different manufacturers. METHODS:HPLC was per-formed on the column of Diamonsil C18 with mobile phase of methanol- water- tetrahydrofuran(75∶24∶1,V/V/V)at a flow rate of 1.0 ml/min,detection wavelength was 254 nm,column temperature was 23 ℃,and the injection volume was 10 μl. RESULTS:The linear range of bifonazole was 50-600 μg/ml (r=0.999 9);RSDs of precision,stability and reproducibility tests were lower than 1%;recovery was 97.71%-101.68%(RSD=1.16%,n=9). The contents of Bifonazole gel samples from 3 manufacturers were more than 10 mg/g,with little difference. CONCLUSIONS:The method is simple and accurate with good separation and re-producibility,and suitable for the content determination of Bifonazole gel. The investigated contents of products from different man-ufactures conform to relevant standards.