[Objective]On the origin and development of stroke research and interpretation. [Methods]Reading from pre-Qin period to the Ming and Qing dynasties in the ancient literature related to stroke the literature, according to the treatment of disease, etiology, pathogenesis, therapeutic principle, prevention and curing of Chinese medical induction, summary, combining the origin of stroke, analysis of pathogenesis and therapeutic principle of stroke, and it is filtered and classified the ancient literature and research, summarizes the extraction.[Methods]Reading and analyzing ancient documents related to the stroke.[Results]The termstrokeand theoretical source inNei Jing, the treatment based on syndrome differentiation is initiated Treatise on Febrile and Miscellaneous Diseases.Jin and Yuan dynasties developed stroke theory;modern perfect stroke syndrome differentiation system. Previously, during the Tang and Song dynasties, it is mainly based on the theories of vital Qi deficiency,pathogenic wind into the argument, treatment of strengthening the body and removal of scattered wind. After the Jin Yuan dynasties, they are internal injury based, wind from the endogenous theories. the treatment is mainly focused on internal injuries. [Conclusion]That ancient physicians paid attention to the etiology and treatment of stroke more, keeping in good health and prevention mentioned less, so we should pay attention to the prevention and recovery.

The article analyzes the TCM etiology, pathogenesis of geriatrics and pathological basis and clinical treatment medication of several common geriatrics. Chinese herb formula with function of invigorating the kidney and promoting blood circulation has the preferable curative effect on geriatrics, so we consider that kidney defi ciency and blood stasis is the main pathogenesis of geriatrics. Invigorating the kidney and promoting blood circulation is an important treatment of geriatrics, and should be followed through the whole therapeutic process.

Objective: To explore the compatibility and application methods of clinical formulas.Methods: In the guidance of monarch,minister,assistant and guide theory, the constructions of prescription were divided into principal agents and lesser agents;500 prescriptions were from 1000 set prescriptions and empirical formulas recorded in pharmacology of traditional Chinese medical formulae teaching material and well-chosen efficacy nostrum written by national lever famous veteran teran doctors of TCM.Then they were analyzed to study the constituting formats of(clinical) formulas and the derivation methods of set prescriptions in clinical application.Results: Through analysis,we found the constituting formats of formulas in terms of single taste single group having principal agents but lesser agents(12.3%),multitude groups having principal agents but lesser agents(13.7%),single taste or single group principal agents with one group lesser agents(14.4%),multitude groups principal agents with one group lesser agents(17.7%),single taste or single group principal agents with multitude groups lesser agents(18.3%) and multitude groups principal agents with multitude groups lesser agents(23.6%) et al.From the 500 randomly extracted prescriptions,among 68.4% prescriptions were present derivation relationship,that is,for adapting new pathogenesis conditions,through methods in terms of replacing principal agents(10.2%),mild recipe lowering to lesser agents(17.0%),two formulas to put together(14.3%),expanding principal agents(16.4%),changing lesser agents(18.7%),principal agents pero-replacing(10.2%) and others(13.2%),changed constituted relation of principal agents or lesser agents,so to generate several formulas possessing new effect characteristics.Conclusion: The(divide) of principal agents and lesser agents has a universal applicability in analyzing the constitutions of formulas;the clinical application and derivation methods of set prescriptions revealed by this method have guide effect to initial(experiencing) clinical worker.

Stomach-qi refers to, in a broad sense, the vital qi of human body, i.e. postnatal vigorous qi and, in a narrow sense, the physiological function of spleen and stomach. Digestive function of spleen and stomach and nutrition get from diet play a key role in keeping and maintaining life and health. Human rely on the qi of food and water they take in, and qi of spleen and stomach transports and transforms the food and water, so we say, “Stomach-qi is the root of human body”. Pathologically, the stomach qi strong or declin is one of the key factors results in diseases. One will be healthy or seldom affected by disease if his or her stomach qi is not damaged; even affected by severe disease, with undamaged stomach-qi and good appetite, one will have a favorable turn. On the contrary, once the stomach-qi is hurt, one will be easily affected by evils or state of the illness will aggravate. So, “If one wants to observe the state of an illness, he or she must observe stomach-qi first; if one wants to treat a patient, he or she must consider the stomach-qi. There would be no worries, if stomach-qi is fine.” Principles for protecting stomach-qi is to treat and regulate the diseases of spleen and stomach in time and to take care of spleen and stomach when one is treating disease of other viscera.

Objective To discuss the clinical effect of Xipayinguyinye on oral bacteria in vitro and gingivitis in vivo.Methods Took the method of agar dilution to measure the minimum inhibitory concentration (MIC) of Xipayinguyinye on Porphyromonas gingivalis ( P.gingivalis),Prevotella intermedia ( P.intermedia ) and Fusobacterium nucleatum( F.nucleatum)in vitro;choose 112 patients with simple gingivitis and they were randomly divided into the research group and control group.The research group(56 cases)received the treatment of Xipayiguyinye,while the control group(56 cases)received the treatment without effect components.Both groups received 7 days of treatment and then observed the changes of sulcus bleeding index ( SBI ) and plaque index ( PLI ) before and after the treatment.Results MICof Xipayiguyinye in vitro was 1.0g/L for P.gingivalis and F.nucleatum and 0.5g/L for P.intermedia.There was no statistifically significant difference in SBI and PLI between two groups before the treatment(P ＞0.05) ;there was significant difference in SBI and PLI of research group before and after the treatment ( P ＜ 0.05 ) ; there was no significant difference in SBI and PLI of control group before and after the treatment( P ＞ 0.05 ) ;there was significant difference in SBI and PLI in SBI and PLI between two groups after the treatment ( P ＜ 0.05 ).Conclusion Xipayiguyinye could prevent bacteriostasis well and decrease the accumulation of dental plaque,reduce SBI and improve the health of the gingiva in vivo.

Objective To investigate the clinical efficacy of Asian proximal femur intramedullary nail antirotation (PFNA-Ⅱ) in the treatment of intertrochanteric fractures in elderly people.Methods From July 2009 to December 2011,127 elderly patients with intertrochanteric fracture were treated by PFNA-Ⅱ.They were 49 cases of male and 78 cases of female,with a mean age of (74.3±15) years.127 elderly patients were classified by modified Evans:type Ⅰ (n=37),typeⅡ (n=42),type Ⅲ (n=26),type Ⅳ (n=15),type V (n=7).We made the statistics on the intraoperative bleeding volume,operation time,incision length,X-light exposure times,and made evaluation of the efficacy of postoperative follow-up and complications by the Harris hip score.Results The average operation time was 42.5 min (35-90) min,the average intraoperative bleeding volume was 107.5 ml (65-410)ml,X-light exposure times were (2.5±1.4) times (2-4) times and the average total incision length was (6.5± 1.8) cm (5.5-11.0) cm.No serious complications or original complications were found during perioperative period.All patients received a 6 to 24 month follow-up (mean 12.5 months in average).The X ray examination showed that the average neck shaft angle was (134±13)° (120°-150°).The average fracture healing time was (14.0±2.5) weeks (11 to 19 weeks).The average hip Harris score was (86.5± 19.5) points (65-100 points).Among them,29 cases (22.83％) were excellent,76 cases (59.8％) were good,20 cases (15.7％) were moderate,2 cases (1.6％) were poor.Totally,excellent and good rate was 82.7％.No complications including hip varus deformity,screw cut-out and femoral shaft fractures were found.There were 14 patients (11.0％) with thigh pain and 5 patients (3.9％) with inner thigh pain.The heavier pain in 4 patients were improved by physical therapy.Conclusions Asian PFNA-Ⅱ has advantages including simple operation,fewer complications,and better clinical efficacy for the treatment of intertrochanteric fractures,but its longterm efficacy and complications still need a large sample and multi-center observation.

Objective To discuss the influence of nursing intervention on psychological state and glu-cose control of patients with diabetes mellitns before and after intensive treatment of insulin pump. Methods 120 patients who were going to receive intensive treatment of insulin pump were divided into the control group and the observation group with 60 patients in each group by simple random method.The two groups both re-ceivecl routine nursing. The observation group was given psychological intervention along with health education by application of progressive dominant content education method. The psychological state and glucose control of the two groups were compared by χ2 test and t test. Results The score of health knowledge and satisfaction degree with health education in the observation group were higher than those of the control group.The score of anxiety and depression in the observation group decreased more significantly and satisfaction rate of glucose control was higher than that of the control group after 14 days of insulin pump treatment. Conclusions Health education to patients with intensive treatment of insulin pump by application of progressive dominant content education method can make patients to master health knowledge easily.Psychological intervention can alleviate the negative emotion of these patients and facilitate better effect of insulin pump treatment.

The main clinical symptoms of Parkinson disease (PD) are resting tremor, muscle rigidity and bradykinesia. There is currently no effective treatment for PD, and dyskinesia symptoms affect the quality of life of patients with PD. The Chinese medicine therapy used for reinforcing kidney and activating blood circulation in treatment of PD was reported to achieve good clinical effects.

Objective:To explore effects of Baoyuan Huoxue Granule on senile type 2 diabetes with Qi deficiency and blood stasis,and expression rates of membrane glucoprotein selectin P(CD62p)and fibrin receptor(PAC-1)in the granule of platelet.Methods:60 cases of senile type 2 diabetes with Qi-deficiency and blood stasis were randomly divided into two groups,a simple western medicine control group(n=30)and a test group(n=30)treated by routine western medicine and Baoyuan Huoxue Granule.The treatment was given 2 months.Their clinical therapeutic effects,and the expression rates of CD62p and PAC-1 before and after treatment were investigated.Results:In the test group,12 cases(40%)were markedly effective,15 cases(50%)effective,3 cases (10%)ineffective,with an effective rate of 90%;In the control group,3 cases(10%)were markedly effective,12(40%) effective,15(50%)ineffective.the effective rate being 50%,with significant difference between the two groups in total effective rate(P

280r/40min). So the PD model was regarded eligible. In the site of lesion in SN, the number and volume of dobaminergic neurons were decreased, and the tissue structure of SN became indistinct, the levels of dopamine (DA), dihydroxyphenylaceticacid (DOPAC), homovanillicacid (HVA) 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleaceticacid (5-HIAA) were more conspicuously reduced than that in uninjured side. TH-immunoreactive cells of substantia nigra compact part were lessened obviously on injured side. The abnormal rotatory behavior of PD rats did not spontaneously disappear during 10 months of continuous observation. Conclusion The PD rat model, which is reproduced by injecting 6-OHDA to selectively destroy dopaminergic neurons in the substantia nigra of rat, is stable and reliable, and demonstrated similar primary pathological changes of PD.