The arterial supply of the human talus in 100 specimens, ranging in age from newborn to 87 years, has been studied by the arterial perfusion method. The talus is supplied by the artery of tarsal canal, the artery of tarsal sinus, the superior arteries of the neck and the branches of the posterior tubercle. These arteries arising diffusely from the three major arteries of the lower leg and anastomose to form the periosteal network on the non-articular surface of the talus. The anastomotic branches between them, ranging from 25 to 150 microns in diameter, form the arterial plexus within the bone. The relations between the characteristics of the arterial distribution and the avascular necrosis of the body of talus after fracture have been discussed.